| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is phbB [H]
Identifier: 54293551
GI number: 54293551
Start: 651283
End: 652023
Strand: Direct
Name: phbB [H]
Synonym: lpl0603
Alternate gene names: 54293551
Gene position: 651283-652023 (Clockwise)
Preceding gene: 54293549
Following gene: 54293552
Centisome position: 19.47
GC content: 40.76
Gene sequence:
>741_bases ATGGATAAAATGATAGCGATTGTAACTGGGGGAACAGGCGGTATTGGTTCTGCTATTAGTCAGCGCTTAGCTGATAGTTA CCAAGTTGTGGCATGCTACTATAAAGATGGAAGACATGAAGAAGCAAAAAAATGGCAAGATGAGCAAAAGCAACTTGGTT ATGACATTGATATCGTATATGGAGATATAGCTCAATATAGTGATTGCGAAAAAATCACATCCCTGGTGATGGAGCGTTAT GGCCGTATAGATGTTTTGGTTAACAACGCAGGCATTACTAAAGACTGCAGTTTAAGAAAAATGACACCTCAACAATGGCA ACAGGTTTTAGACGCCAACTTGACCAGTGTATTCAATATGACGCGCAATGTCGTTCCAGTGATGTTGGAAAGAGGTTATG GCCGTATCATCAGTATATCTTCAATCAATGGAAAAAAAGGCCAGTTTGGCCAATGCAATTATGCTTCCACCAAGGCGGCT TTATTTGGTTTTACCAAGAGTCTTGCATTAGAAGTAGCAAGTAAAGGTATTACGGTAAACACAGTGTCGCCTGGGTATAT TGAGACTTCTATGCTCGCTGCATTGAAAGAAGATGTACTCAATTCAATCATATCCAGTATTCCTGTTGGTCGATTGGGAT ACCCAAAAGAAATTGCAGATGCCGTTGCATTTTTAGCATCACCAGATAGCGGATTTATTACGGGGGCAAATCTGGACGTC AATGGTGGTCAGTATATGTAG
Upstream 100 bases:
>100_bases AATTATTATCACCAACTTAGTATTATATATATGTCATTGACAAGAAAGTAAAATTAGATTGTAGTAATGTAATGTTACCT AGCAACAAAAGGAGTTGTCG
Downstream 100 bases:
>100_bases TCAGAGTTTGATTCACCGATTAAGAATCTCAAGAGGTTTTGTGAACATATTATTTACTGTTCGCAAGGCACCTTGGGATT TTGAAAAAGTGGCTGCGATC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 246
Protein sequence:
>246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIISISSINGKKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETSMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM
Sequences:
>Translated_246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIISISSINGKKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETSMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM >Mature_246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIISISSINGKKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETSMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=36.4341085271318, Blast_Score=147, Evalue=6e-36, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=35.9183673469388, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=36.2139917695473, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI59889578, Length=189, Percent_Identity=37.5661375661376, Blast_Score=112, Evalue=2e-25, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=32.8185328185328, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=30.7392996108949, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=32.5102880658436, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.8548387096774, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI4504505, Length=207, Percent_Identity=30.4347826086957, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=30.8880308880309, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=32.5443786982249, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=33.160621761658, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=34.5744680851064, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=31.0160427807487, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=28.4263959390863, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=26.6949152542373, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI157739938, Length=132, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=217, Percent_Identity=24.4239631336406, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI302344755, Length=121, Percent_Identity=34.7107438016529, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4503301, Length=198, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=24.7368421052632, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=30.8080808080808, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI150247226, Length=120, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI142976729, Length=217, Percent_Identity=28.110599078341, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=42.798353909465, Blast_Score=201, Evalue=4e-53, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.8461538461538, Blast_Score=137, Evalue=7e-34, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=33.0578512396694, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=33.739837398374, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=30.8333333333333, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=28.0487804878049, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=29.9180327868852, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.1740890688259, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.2904564315353, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1786812, Length=208, Percent_Identity=27.8846153846154, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.6451612903226, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=26.2745098039216, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1786701, Length=150, Percent_Identity=30.6666666666667, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=43.0894308943089, Blast_Score=167, Evalue=4e-42, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=42.1052631578947, Blast_Score=166, Evalue=9e-42, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.469387755102, Blast_Score=130, Evalue=7e-31, Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=34.2857142857143, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=32.319391634981, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=31.4516129032258, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=34.5291479820628, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=31.496062992126, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=32.7067669172932, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=32.4324324324324, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.4182509505703, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.7878787878788, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=30.7086614173228, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538182, Length=233, Percent_Identity=30.9012875536481, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=31.2252964426877, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.8850574712644, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=27.5132275132275, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.8939393939394, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193203117, Length=239, Percent_Identity=27.6150627615063, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI193203115, Length=239, Percent_Identity=27.6150627615063, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=30.3501945525292, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=27.7992277992278, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=28.0898876404494, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.0813008130081, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=28.2352941176471, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=28.9340101522843, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.5384615384615, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=26.7015706806283, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=115, Percent_Identity=41.7391304347826, Blast_Score=101, Evalue=1e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=205, Percent_Identity=25.8536585365854, Blast_Score=63, Evalue=3e-11, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=36.9047619047619, Blast_Score=145, Evalue=3e-35, Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=35.1239669421488, Blast_Score=144, Evalue=4e-35, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=34.136546184739, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=36.2204724409449, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=7e-29, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=29.3388429752066, Blast_Score=118, Evalue=5e-27, Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=34.8258706467662, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=29.9180327868852, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI18859837, Length=228, Percent_Identity=32.0175438596491, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI17737361, Length=231, Percent_Identity=31.1688311688312, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.3505154639175, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24641232, Length=214, Percent_Identity=30.8411214953271, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=30.0518134715026, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24581726, Length=171, Percent_Identity=29.2397660818713, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007236, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640442, Length=215, Percent_Identity=31.1627906976744, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665264, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26711; Mature: 26711
Theoretical pI: Translated: 6.00; Mature: 6.00
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVY CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE GDIAQYSDCEKITSLVMERYGRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNM CCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH TRNVVPVMLERGYGRIISISSINGKKGQFGQCNYASTKAALFGFTKSLALEVASKGITVN HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE TVSPGYIETSMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEC NGGQYM CCCCCC >Mature Secondary Structure MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVY CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE GDIAQYSDCEKITSLVMERYGRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNM CCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH TRNVVPVMLERGYGRIISISSINGKKGQFGQCNYASTKAALFGFTKSLALEVASKGITVN HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE TVSPGYIETSMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEC NGGQYM CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]