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The map label for this gene is pdxH [H]

Identifier: 54293531

GI number: 54293531

Start: 630579

End: 631226

Strand: Direct

Name: pdxH [H]

Synonym: lpl0582

Alternate gene names: 54293531

Gene position: 630579-631226 (Clockwise)

Preceding gene: 54293530

Following gene: 54293532

Centisome position: 18.85

GC content: 39.04

Gene sequence:

>648_bases
ATGAGCAAATTTAGAAGTCTTGCGGATATTAGACGAGATTATGGTGAGTTGCAGCTCAGTGAAGAATCCGCTGAAAATGA
TCCCATTTCTCAATTCAAACTATGGTTTGATGATGTATTACTAAATGAAAAAAATGATCCCACGGCAATGGTTCTGTCTA
CAGTAGATGAAAAGGGCTATCCAGATTCCAGAGTTGTCTTATTAAAAGGATTAGAGAACGGTAATTTTATCTTTTATACC
AATTATCAAAGTGCCAAGGCAATGCAAATACAAAAGAATCCTTATGCCGCACTTAATTTTTATTGGCCTCAAATGGCAAG
ACAAGTACGTGTTCGTGGCCGAGTAAAAAAAATCAGCAGCGAGCAATCCGATGCTTATTTCTCCTCCAGACCTATAAAAA
GTCAGTTTAGCGCGATTGTTTCTCCCCAAAGCCAAGAAATTCTGGATAGGATTTCTTTAGAAGATGCTTTAAATCAGTTG
ATTGAAGAATATGGCCAAAAACCCGTAGTCAGACCGGAAAACTGGGGTGGATATATGATAATCCCGGATGAGATTGAGTT
TTGGCAGGGTAGAGATAACAGATTACATGATCGAATTCATTATTACCGGCATGGTCATGAATGGACGCACCGTAGATTGG
CACCTTGA

Upstream 100 bases:

>100_bases
TATGCAAGAAGTCGATTGAAAAATTTTAAATGTAAAATGTATCGCAAATTATAAATTTTAGAGAGTATAATTATTTACAT
TTTTTTAGTGAAGGTTTGCT

Downstream 100 bases:

>100_bases
CCGGCAGTTTTTGTCATCATTCCTGCCGGCATCATTTTACTATTGAGATATAGAAGGATGAGTTTTCATGGAAGGTTGGT
TAATGGTTGAATTCTTTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYT
NYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPIKSQFSAIVSPQSQEILDRISLEDALNQL
IEEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP

Sequences:

>Translated_215_residues
MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYT
NYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPIKSQFSAIVSPQSQEILDRISLEDALNQL
IEEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP
>Mature_214_residues
SKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYTN
YQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPIKSQFSAIVSPQSQEILDRISLEDALNQLI
EEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=228, Percent_Identity=39.4736842105263, Blast_Score=167, Evalue=7e-42,
Organism=Escherichia coli, GI1787926, Length=213, Percent_Identity=40.8450704225352, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17553712, Length=206, Percent_Identity=41.747572815534, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6319509, Length=208, Percent_Identity=37.5, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45551845, Length=228, Percent_Identity=40.3508771929825, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24644901, Length=228, Percent_Identity=40.3508771929825, Blast_Score=153, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24644903, Length=146, Percent_Identity=28.7671232876712, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 25264; Mature: 25132

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGY
CCHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCC
PDSRVVLLKGLENGNFIFYTNYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISS
CCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCC
EQSDAYFSSRPIKSQFSAIVSPQSQEILDRISLEDALNQLIEEYGQKPVVRPENWGGYMI
CCCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
IPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP
ECCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
SKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGY
CHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCC
PDSRVVLLKGLENGNFIFYTNYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISS
CCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCC
EQSDAYFSSRPIKSQFSAIVSPQSQEILDRISLEDALNQLIEEYGQKPVVRPENWGGYMI
CCCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
IPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP
ECCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA