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The map label for this gene is cdsA [H]

Identifier: 54293494

GI number: 54293494

Start: 591240

End: 592037

Strand: Direct

Name: cdsA [H]

Synonym: lpl0543

Alternate gene names: 54293494

Gene position: 591240-592037 (Clockwise)

Preceding gene: 54293493

Following gene: 54293495

Centisome position: 17.67

GC content: 35.71

Gene sequence:

>798_bases
ATGTTTATGCAACGTTTGATTACGACATTAATATTAGCGCCTTTGGTTTTGCTTGCTATTTTCTATGCGCCTTCCTGGAT
TTTATGGGGTGTTGTTTTTGTGATACTCCTGCTTGCGGGAATTGAAAGTTTGAAATTGATTCCTGTTCACAATTTATCTA
TGCAGGCTTGTTTTTTGATATTTCTATTGATGTGCTTTTGGGCATGTGGCTATTTATATCCCTATTGGTTAAGCGTGGGG
TTATTCGTTTGGCTATTCAATGGCTTGGCAATCCTCACTTATCCACGCTCACAAAATTATTGGGGCTATCCAATGATTGT
TGCAATAGCCTGTTTGATATTGTTACCTTTATTTACTCAAAGTCTTATTCAAATTTCTTTTTTACAGCAAGGAAAGGAAT
TACTTGTCTATTTGCTTTTTTTAATTTGGGCTTCTGATATTGGTGCTTATCTCACTGGAAAACAATGGGGAAAACATAAA
TTAATCCCTAAAGTTAGTCCGGGTAAATCTTGGGAAGGTGTTACAGGCGGGGTTATTTTAGCCATGATAGTCGCGACTTT
GGGCTATTATTATTTTATACCTTACTCAATTTATATATGGTTTGGTTTAGCATTGTCTACTGTAGTTATTTCAATTTTTG
GTGATTTGTTCATCAGTATATTAAAACGGCGTTGTCAATTAAAAGATACTGGAAATATTATTCCAGGTCATGGCGGTATA
TTAGATCGACTGGATAGTCTAATTGCCGCGTTGCCATGGTTTTACTTTGGATTAACCTACATACCACTGGGAATTTAA

Upstream 100 bases:

>100_bases
CCTGATTTTAATGAGCATGAGTTTGAATTGGCATTGATTTCTTTTTCCAAGCGGGCAAGAAGGTTTGGGCAAATTTCACA
ATCTGAATAAAGGTAAAACC

Downstream 100 bases:

>100_bases
TTTTCTGGTCGTATCAATTTTTGGATAACGATATGCTTTCAACGTTGCTGTACTTTTTATTAGCATTGGTATTGTTAGTC
ACCATACATGAATACGGCCA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MFMQRLITTLILAPLVLLAIFYAPSWILWGVVFVILLLAGIESLKLIPVHNLSMQACFLIFLLMCFWACGYLYPYWLSVG
LFVWLFNGLAILTYPRSQNYWGYPMIVAIACLILLPLFTQSLIQISFLQQGKELLVYLLFLIWASDIGAYLTGKQWGKHK
LIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRCQLKDTGNIIPGHGGI
LDRLDSLIAALPWFYFGLTYIPLGI

Sequences:

>Translated_265_residues
MFMQRLITTLILAPLVLLAIFYAPSWILWGVVFVILLLAGIESLKLIPVHNLSMQACFLIFLLMCFWACGYLYPYWLSVG
LFVWLFNGLAILTYPRSQNYWGYPMIVAIACLILLPLFTQSLIQISFLQQGKELLVYLLFLIWASDIGAYLTGKQWGKHK
LIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRCQLKDTGNIIPGHGGI
LDRLDSLIAALPWFYFGLTYIPLGI
>Mature_265_residues
MFMQRLITTLILAPLVLLAIFYAPSWILWGVVFVILLLAGIESLKLIPVHNLSMQACFLIFLLMCFWACGYLYPYWLSVG
LFVWLFNGLAILTYPRSQNYWGYPMIVAIACLILLPLFTQSLIQISFLQQGKELLVYLLFLIWASDIGAYLTGKQWGKHK
LIPKVSPGKSWEGVTGGVILAMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRCQLKDTGNIIPGHGGI
LDRLDSLIAALPWFYFGLTYIPLGI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=276, Percent_Identity=32.2463768115942, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787677, Length=168, Percent_Identity=37.5, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29970; Mature: 29970

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMQRLITTLILAPLVLLAIFYAPSWILWGVVFVILLLAGIESLKLIPVHNLSMQACFLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCCHHHHHHHH
FLLMCFWACGYLYPYWLSVGLFVWLFNGLAILTYPRSQNYWGYPMIVAIACLILLPLFTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SLIQISFLQQGKELLVYLLFLIWASDIGAYLTGKQWGKHKLIPKVSPGKSWEGVTGGVIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRCQLKDTGNIIPGHGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
LDRLDSLIAALPWFYFGLTYIPLGI
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFMQRLITTLILAPLVLLAIFYAPSWILWGVVFVILLLAGIESLKLIPVHNLSMQACFLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCCHHHHHHHH
FLLMCFWACGYLYPYWLSVGLFVWLFNGLAILTYPRSQNYWGYPMIVAIACLILLPLFTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
SLIQISFLQQGKELLVYLLFLIWASDIGAYLTGKQWGKHKLIPKVSPGKSWEGVTGGVIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AMIVATLGYYYFIPYSIYIWFGLALSTVVISIFGDLFISILKRRCQLKDTGNIIPGHGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
LDRLDSLIAALPWFYFGLTYIPLGI
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]