| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is rpoA [H]
Identifier: 54293346
GI number: 54293346
Start: 443923
End: 444915
Strand: Direct
Name: rpoA [H]
Synonym: lpl0395
Alternate gene names: 54293346
Gene position: 443923-444915 (Clockwise)
Preceding gene: 54293345
Following gene: 54293347
Centisome position: 13.27
GC content: 37.06
Gene sequence:
>993_bases ATGTATACTGAAATCAATGAAATGTTGACGCCTAAGGTTCTCAAAGTACAGGCCGAGTCGCCCTATAAAGCTAGAATAGT TTTAGAACCTTTGGAGCGAGGTTTTGGTCACACCCTCGGCAATGCTTTGAGAAGAATCTTATTGTCATCCATGCCAGGTA GTGCCATTACAGAAGCTTCTATCGATGGTGTTTTGCATGAATATAGTACTATTGAAGGTGTTCAGGAAGATGTGGTTGAT TTGTTGCTTAACCTAAAATCAGTTGCTATCAAATTGACTGTAGGAAACGAAGCTCAGATTACCTTAAATAAAGAAGGACC ATGTCAAGTTACAGCTGGTGATATTCAGTTGACTCATGGCCAAGAAATTATTAATCCAGAACTTGTCATAGCCAATCTCA ATGAAAAGGGTAAATTAAATATGACTCTTAAAGTTGAAAGAGGTATTGGCTTTCATAATACTGATGCATTTGTTCGCTAT CATGATGATGAAATTGAGAAAAAGACGGTTGGAAAGTTAAAAATAGACAACAGTTTTTCTCCAGTGAAGAAAGTGGCTTA TTTCGTCGACAGTGCGCGTGTAGAAAACAGAACAGATTTAGATAAGCTTACTATTGAATTAGAAACTAACGGTACTATCG ATGCTGAAGAGGCAATAAGAATATCTGCTAGTATACTACAAAGACAGCTTCATGCGTTTGTTGACATGAAATTTGAAGAA TCACGTGCTGACAATAAAGAGCGTAATGATTTTGATCCTGTATTATTACGTTCAGTGGATGATTTGGAGTTGACTGTTCG ATCAGCTAATTGTTTAAAAGCTGAAAACATTCATTATATAGGCGATTTGGTTCAAAGAACAGAAAGTGAATTATTGAAGA CACCTAATCTTGGTAAGAAATCACTAACTGAAATTAAAGACGTTTTAGCGTCTCGATCATTATCGCTGGGTATGAAACTT GAGAATTGGCCGCCAGCAAGCCTTGGCGAGTAA
Upstream 100 bases:
>100_bases TACATTTTCTACAGCACCAACGTTAATGGATTTATCTTCAGACTACAACGTAAACCTTGTTGTAGAACTTTACTCTAAGT AAGCTCGGAGAGATAGCTGA
Downstream 100 bases:
>100_bases TATTTAGGAGTCTTTGTTATGCGTCACCGTAATTCCGGACGTAGTTTTAGTCGTACCAGTAGCCACCGTAAGGCTATGTT TTCTAATATGTGTTGTTCTT
Product: DNA-directed RNA polymerase subunit alpha
Products: NA
Alternate protein names: RNAP subunit alpha; RNA polymerase subunit alpha; Transcriptase subunit alpha [H]
Number of amino acids: Translated: 330; Mature: 330
Protein sequence:
>330_residues MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEASIDGVLHEYSTIEGVQEDVVD LLLNLKSVAIKLTVGNEAQITLNKEGPCQVTAGDIQLTHGQEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRY HDDEIEKKTVGKLKIDNSFSPVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEE SRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKKSLTEIKDVLASRSLSLGMKL ENWPPASLGE
Sequences:
>Translated_330_residues MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEASIDGVLHEYSTIEGVQEDVVD LLLNLKSVAIKLTVGNEAQITLNKEGPCQVTAGDIQLTHGQEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRY HDDEIEKKTVGKLKIDNSFSPVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEE SRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKKSLTEIKDVLASRSLSLGMKL ENWPPASLGE >Mature_330_residues MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEASIDGVLHEYSTIEGVQEDVVD LLLNLKSVAIKLTVGNEAQITLNKEGPCQVTAGDIQLTHGQEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRY HDDEIEKKTVGKLKIDNSFSPVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEE SRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKKSLTEIKDVLASRSLSLGMKL ENWPPASLGE
Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]
COG id: COG0202
COG function: function code K; DNA-directed RNA polymerase, alpha subunit/40 kD subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the RNA polymerase alpha chain family [H]
Homologues:
Organism=Escherichia coli, GI1789690, Length=331, Percent_Identity=60.4229607250755, Blast_Score=395, Evalue=1e-111,
Paralogues:
None
Copy number: 850 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 560 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 6847 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 7,000 Molecules/Cell In: Glucose minimal media
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011261 - InterPro: IPR011262 - InterPro: IPR009025 - InterPro: IPR011263 - InterPro: IPR011260 - InterPro: IPR011773 - ProDom: PD001179 [H]
Pfam domain/function: PF01000 RNA_pol_A_bac; PF03118 RNA_pol_A_CTD; PF01193 RNA_pol_L [H]
EC number: =2.7.7.6 [H]
Molecular weight: Translated: 36761; Mature: 36761
Theoretical pI: Translated: 4.99; Mature: 4.99
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEAS CCCCHHHHCCCEEEEEECCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH IDGVLHEYSTIEGVQEDVVDLLLNLKSVAIKLTVGNEAQITLNKEGPCQVTAGDIQLTHG HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCEEEEECCEEEECC QEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRYHDDEIEKKTVGKLKIDNSFS CCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEECCCHHHHHHCCEEEECCCCC PVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEE HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH SRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKK HCCCCCCCCCCCHHHHCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHH SLTEIKDVLASRSLSLGMKLENWPPASLGE HHHHHHHHHHHCCHHCCEEECCCCCCCCCC >Mature Secondary Structure MYTEINEMLTPKVLKVQAESPYKARIVLEPLERGFGHTLGNALRRILLSSMPGSAITEAS CCCCHHHHCCCEEEEEECCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH IDGVLHEYSTIEGVQEDVVDLLLNLKSVAIKLTVGNEAQITLNKEGPCQVTAGDIQLTHG HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCEEEEECCEEEECC QEIINPELVIANLNEKGKLNMTLKVERGIGFHNTDAFVRYHDDEIEKKTVGKLKIDNSFS CCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEECCCHHHHHHCCEEEECCCCC PVKKVAYFVDSARVENRTDLDKLTIELETNGTIDAEEAIRISASILQRQLHAFVDMKFEE HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH SRADNKERNDFDPVLLRSVDDLELTVRSANCLKAENIHYIGDLVQRTESELLKTPNLGKK HCCCCCCCCCCCHHHHCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHH SLTEIKDVLASRSLSLGMKLENWPPASLGE HHHHHHHHHHHCCHHCCEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA