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The map label for this gene is rpoB [H]

Identifier: 54293314

GI number: 54293314

Start: 419111

End: 423217

Strand: Direct

Name: rpoB [H]

Synonym: lpl0362

Alternate gene names: 54293314

Gene position: 419111-423217 (Clockwise)

Preceding gene: 54293313

Following gene: 54293315

Centisome position: 12.53

GC content: 40.42

Gene sequence:

>4107_bases
ATGGCAGTTGCAGAAGCTAAACCTCAATATTCGCATGCTGAGAAAAAACGATTTCGCAAAAGCTTTGGTAAGCAGACAGA
TATAATGCCAATACCGAATCTGCTTGAAATTCAACTTAAATCCTACAGGGATTTTCTTCAAACTGATACTAAATTAAGCG
AACAACTGAATACGGGATTGCATGCTGCATTTTCTTCTGTATTTCCTATCGAAAGCTTTTCTGGTAATGCAAGACTTGAA
TACGTCGGATACAAGCTTGGAGAGCCTGCATTTGATGTTCGCGAATGCAAACTACGAGGGCTAACTTACTCAGCTCCTCT
AAGAGTCAAGATCAGACTCGTTGTGCTTGATAAAGATGCAAGCGATGATCCTAAGCCTATAAAGGATATTAGAGAGCAAG
ATGTTTTTATGGGGGAAATTCCCCTAATGACTGACGTTGGTACGTTTGTGGTCAATGGAACGGAACGTGTTGTTGTTTCA
CAATTACATCGTTCTCCTGGAGTTATATTTGAACATGACAAGGGAAAAACTCACTCTTCAGGTAAATTGCTCTATTCCGC
ACGAATAATACCTTATCGTGGTTCATGGTTAGACTTTGAATTCGATCCTAAAGATTGCGTTTATGTACGTATTGACAGAC
GTCGTAAACTGCCAGTGACCATTTTGCTCAGAGCATTGGGCTACGAAGCAGAAGATATATTAAACGAATTTTTTGAAACA
ACTTGTTGTCATTTAAAAAATGGCGAATACCACATCGATTTAATTCCACAGCGTTTGCGTGGTGAAATCGCTTCATTCGA
TATTCATGTTCCTGAAACTGGAGAGCTTATCGTAGAGCAAGGTCGTCGAATTACCGCAAGACATATAAAGCAAATGGAAA
AAAGCCAAATGCAGGATCTAGTGGTACCAAGAGACTATTTAATTGGAAAAACATTAGCAAAAAATATTATTGATACCTCA
ACCGGTGAATTTCTGGCTCAAGCGAATGATGAGATAACGGAAGAGCTTTTAGATGCTATGGCTAGCCATGGTATTTTACA
AATTGATATGATCTATACTAACGATTTGGATCATGGTTCTTACATATCGGATACATTAAAGATTGATCCCACAGGATCAC
AACTAGAAGCACTCGTTGAAATTTATCGCATGATGCGCCCTGGAGAGCCTCCTACAAAGGAAGCTGCTGAGGCACTATTT
AAAAATCTATTCTTTGTTGAAGAAAGATATGATCTATCTGCTGTTGGCAGAATGAAATTTAATCGTCGGGTAGGAATTAA
GAGTGACGAAGGCCCAGGCACTTTAACGAAGGAAGACATTTTATCTGTCATTAAAACACTGATAGATATTCGAAATGGAA
TAGGGATGGTTGATGATATCGATCATCTAGGAAATCGTAGGGTAAGAAGTGTTGGTGAAATGACCGAAAATCAGTTTAGA
GTAGGTCTTGTTCGTGTTGAACGTGCTGTTAAAGAGCGCTTAAGTTTGGTTGAATCTGAAAATCTGATGCCACAGGACTT
AATTAACGCAAAACCGGTGTCCGCCGCAATTAAAGAGTTTTTTGGATCCAGTCAGTTATCACAGTTTATGGATCAAGTGA
ATCCATTATCTGGTGTTACGCATAAAAGACGTGTATCGGCTCTTGGGCCAGGTGGTTTAACACGTGAGCGTGCTGGATTT
GAAGTCCGTGACGTGCATACAACACACTATGGTCGTGTGTGCCCAATTGAAACGCCTGAAGGACCAAATATTGGTCTAAT
CAATTCACTGTCAGTTTATGCAAGAACTAACGAATATGGATTTATTGAAACTCCTTGTCGAAAGGTTGTTAATGGGCGTG
TGACAGATGAAGTTGAATACCTATCGGCTATTGAGGAAGTTGATCAATACATTGCACAATCTAATGTTGAATTAGACGCA
CAAGGAAATATTCTTGCTGACTTAGTTCCTTGCAGACATCAAAATGAATTTTCACTGACTACTCCGGATAAAATCAACTA
CATGGATGTCTCGCCCAAGCAAATTGTGTCAGTTGCAGCTTCATTGATTCCGTTTTTAGAGCACGATGATGCAAACAGAG
CATTAATGGGTTCAAACATGCAACGACAGGCTGTGCCAACCTTGCGTTCAGAAAAGCCCTTGGTTGGGACCGGTATGGAA
AGAATCGTTGCATCTGATTCAGGAGTTTCAGTTGTTGCGAAGAGAGGTGGAGTTATTGATCTGGTTGATGCTTCTCGTAT
TGTTGTTCGAGTGAATGACGACGAAACAACAGCAGGGGAAACAGGGGTAGATATTTATAACTTAACCAAGTATTTCCGTT
CTAACCAGGATACTTGTATCAATCAAAGACCCATAGTATCAACAGGTGATCGAATTCAACGAGGTGATGTCCTGGCTGAT
GGTCCATGTACAGATATGGGTGAATTGGCTCTTGGACAGAATCTACTGGTAGCGTTTATGCCTTGGAATGGTTATAACTT
TGAGGATTCCATTCTTATATCTGAACGAATCGTTCATGACGACAGATTCACTACTATCCACATCGAAGAGCTAACATGTA
TAGCTCGAGATACCAAATTAGGTACGGAAGAAATTACAGCAGATATTCCCAATGTAGGCGAGTCTGCACTCTCTAATTTA
GATGAATCTGGAGTTGTTTACATAGGTGCAGAAGTTAAAGCAGGTGATATTCTTGTGGGGAAAGTAACTCCTAAAGGAGA
AACCCAACTAACTCCAGAAGAAAAACTGTTAAGAGCCATCTTTGGTGAAAAAGCTTCAGATGTTAAAGATTCATCTTTGA
GAGTTCCATCAGGTATGAATGGAACAGTGATCGATGTACAAGTCTTTACCCGTGATGGACTTGAAAAGGATGCTCGTGCT
AAAAGCATTGAAGAAGAGCATCTGGCTCGAGTTCGCAAGGATTTAATAGACGAACGGCGTATTCGTGAAGAAGACATCTA
TCATAGAGTTTCTCATTTGCTGTTGGATAAGGTTGCAACAGGCGGTCCTGGAAGCCTAAAGCCTGGATCTAAAATCACCC
AGGATTACCTGGATAAAGTTGAAAGAGAAAAGTGGTTTGATATTCGTATAGAAGATGACGCAATTAGTCAGCAACTTGAA
CAACTATCCAAGCAACTGGAACTTTTAACAAAAGAAATGGAAAAGCGCTTTAACGACAGTAGAAAGAAAATTATCCAGGG
AGACGATTTAGCTCCTGGTGTATTAAAAATTGTTAAAGTGTATTTGGCTGTTAAAAGAAGAATTCAGCCTGGAGACAAAA
TGGCAGGTCGTCATGGAAACAAGGGTGTGATCTCCATTGTTGTTCCAGTTGAAGATATGCCGCATATGGAAGATGGAACG
GCTGTAGATATCGTTCTTAATCCATTGGGCGTACCATCGCGAATGAATATCGGCCAGGTTCTTGAAACGCATCTGGGACT
AGCTGCCAAAGGATTGGGAAGAAAGATTGCACAGATGCTTGATGAAAAGCAAACACCTGAAGCAATAAAAGCATACCTTG
AGAAAATTTATAATCATGACGGAGTGCAGCGTGTTAATTTGAAATGCCTCAATGATGATGAATTGATGACACTGGCGGAT
AACCTGAGAGCTGGTGTGCCGATGGCAACTCCTGTCTTTGATGGTGCTACTGAGCAAGAAATCAAAAGTATGCTGCAGTT
AGCAGATTTGCCAGCAGATGGTAAAACCGTGTTGATAGATGGTCGAACAGGTAATAAATTTGATAATCCGGTTACTGTAG
GCTACATGTATATGTTGAAGTTAAACCATTTGGTTGATGATAAGATGCATGCTCGTTCAACTGGATCATACAGTTTGGTC
ACTCAACAACCACTTGGCGGTAAAGCACAGTTTGGTGGTCAGCGTTTTGGTGAGATGGAAGTATGGGCATTAGAAGCATA
TGGTGCAGCATACACTTTACAAGAAATGTTAACCGTAAAATCAGATGACGTCGGAGGTCGAACAAAGATCTATAAAAATA
TAGTCGATGGAGATCATCGTATGGACCCAGGAATGCCTGAATCCTTCAATGTATTATTGAAGGAAATTAGAGCACTGGGA
ATTGATATCGAGTTGGAGCATGACTAA

Upstream 100 bases:

>100_bases
GTTAAATAATTAAAATATAGCAGTATTTAAGAACCCAGCCATGTTCACATGGCTGGGTTTACTCGTTTGAAAATCATCAA
TAATTTACAGAGGAACCACC

Downstream 100 bases:

>100_bases
CTCATCAGCGATACATACTGACTAACCATTTTTTGGAGGCATAGACTTGGCTACCCTAAGCAACGACCCAATGAAAAAAG
CACCAGTAATGAGTGACTTA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1368; Mature: 1367

Protein sequence:

>1368_residues
MAVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGLHAAFSSVFPIESFSGNARLE
YVGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDASDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVS
QLHRSPGVIFEHDKGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVTILLRALGYEAEDILNEFFET
TCCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDLVVPRDYLIGKTLAKNIIDTS
TGEFLAQANDEITEELLDAMASHGILQIDMIYTNDLDHGSYISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALF
KNLFFVEERYDLSAVGRMKFNRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFR
VGLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVTHKRRVSALGPGGLTRERAGF
EVRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYGFIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDA
QGNILADLVPCRHQNEFSLTTPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGME
RIVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCINQRPIVSTGDRIQRGDVLAD
GPCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHDDRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNL
DESGVVYIGAEVKAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARA
KSIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKVEREKWFDIRIEDDAISQQLE
QLSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGT
AVDIVLNPLGVPSRMNIGQVLETHLGLAAKGLGRKIAQMLDEKQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLAD
NLRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNPVTVGYMYMLKLNHLVDDKMHARSTGSYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALG
IDIELEHD

Sequences:

>Translated_1368_residues
MAVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGLHAAFSSVFPIESFSGNARLE
YVGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDASDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVS
QLHRSPGVIFEHDKGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVTILLRALGYEAEDILNEFFET
TCCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDLVVPRDYLIGKTLAKNIIDTS
TGEFLAQANDEITEELLDAMASHGILQIDMIYTNDLDHGSYISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALF
KNLFFVEERYDLSAVGRMKFNRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFR
VGLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVTHKRRVSALGPGGLTRERAGF
EVRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYGFIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDA
QGNILADLVPCRHQNEFSLTTPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGME
RIVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCINQRPIVSTGDRIQRGDVLAD
GPCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHDDRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNL
DESGVVYIGAEVKAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARA
KSIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKVEREKWFDIRIEDDAISQQLE
QLSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGT
AVDIVLNPLGVPSRMNIGQVLETHLGLAAKGLGRKIAQMLDEKQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLAD
NLRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNPVTVGYMYMLKLNHLVDDKMHARSTGSYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALG
IDIELEHD
>Mature_1367_residues
AVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGLHAAFSSVFPIESFSGNARLEY
VGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDASDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVSQ
LHRSPGVIFEHDKGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVTILLRALGYEAEDILNEFFETT
CCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDLVVPRDYLIGKTLAKNIIDTST
GEFLAQANDEITEELLDAMASHGILQIDMIYTNDLDHGSYISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALFK
NLFFVEERYDLSAVGRMKFNRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFRV
GLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVTHKRRVSALGPGGLTRERAGFE
VRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYGFIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDAQ
GNILADLVPCRHQNEFSLTTPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGMER
IVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCINQRPIVSTGDRIQRGDVLADG
PCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHDDRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNLD
ESGVVYIGAEVKAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARAK
SIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKVEREKWFDIRIEDDAISQQLEQ
LSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGTA
VDIVLNPLGVPSRMNIGQVLETHLGLAAKGLGRKIAQMLDEKQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLADN
LRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVT
QQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALGI
DIELEHD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=261, Percent_Identity=31.4176245210728, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI212286172, Length=261, Percent_Identity=31.4176245210728, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI4505941, Length=114, Percent_Identity=39.4736842105263, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI238908505, Length=78, Percent_Identity=44.8717948717949, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI238908503, Length=78, Percent_Identity=44.8717948717949, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1790419, Length=1361, Percent_Identity=69.1403379867744, Blast_Score=1947, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=247, Percent_Identity=31.5789473684211, Blast_Score=114, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25144348, Length=247, Percent_Identity=30.3643724696356, Blast_Score=109, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324781, Length=246, Percent_Identity=32.520325203252, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=248, Percent_Identity=31.8548387096774, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325267, Length=248, Percent_Identity=33.4677419354839, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136444, Length=247, Percent_Identity=32.3886639676113, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17647877, Length=246, Percent_Identity=31.7073170731707, Blast_Score=113, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17136446, Length=259, Percent_Identity=32.4324324324324, Blast_Score=103, Evalue=1e-21,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 152687; Mature: 152556

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAAFSSVFPIESFSGNARLEYVGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDA
HHHHHHCCCCCCCCCCCEEEEECEECCCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCC
SDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVSQLHRSPGVIFEHDKGKTHSS
CCCCHHHHHHHHCCCEECCCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCC
GKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVTILLRALGYEAEDILNEFFET
CEEEEEEEEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHH
TCCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDL
HHHEECCCCEEEEECCHHHCCCHHEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
VVPRDYLIGKTLAKNIIDTSTGEFLAQANDEITEELLDAMASHGILQIDMIYTNDLDHGS
CCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
YISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALFKNLFFVEERYDLSAVGRMKF
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
VGLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVT
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCC
HKRRVSALGPGGLTRERAGFEVRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYG
HHHHHCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECEEEEEECCCCC
FIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDAQGNILADLVPCRHQNEFSLT
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCCEECC
TPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGME
CCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCHH
RIVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCI
HHHCCCCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCC
NQRPIVSTGDRIQRGDVLADGPCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHD
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHCCC
DRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNLDESGVVYIGAEVKAGDILVG
CCEEEEEEEHEEEEHHCCCCCHHHHHCCCCCCCHHHHHCCCCCCEEEEECEECCCCEEEE
KVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARA
ECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHH
KSIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EREKWFDIRIEDDAISQQLEQLSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKV
HHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHH
YLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGTAVDIVLNPLGVPSRMNIGQV
HHHHHHHCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
LETHLGLAAKGLGRKIAQMLDEKQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLAD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHH
NLRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNPVTVGYMYMLK
HHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHH
LNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVK
HHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALGIDIELEHD
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
AVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAAFSSVFPIESFSGNARLEYVGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDA
HHHHHHCCCCCCCCCCCEEEEECEECCCCCCCHHHHHHCCCEECCCEEEEEEEEEEECCC
SDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVSQLHRSPGVIFEHDKGKTHSS
CCCCHHHHHHHHCCCEECCCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCC
GKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVTILLRALGYEAEDILNEFFET
CEEEEEEEEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHH
TCCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDL
HHHEECCCCEEEEECCHHHCCCHHEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
VVPRDYLIGKTLAKNIIDTSTGEFLAQANDEITEELLDAMASHGILQIDMIYTNDLDHGS
CCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
YISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALFKNLFFVEERYDLSAVGRMKF
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
VGLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVT
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCC
HKRRVSALGPGGLTRERAGFEVRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYG
HHHHHCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECEEEEEECCCCC
FIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDAQGNILADLVPCRHQNEFSLT
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCCEECC
TPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGME
CCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCHH
RIVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCI
HHHCCCCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCC
NQRPIVSTGDRIQRGDVLADGPCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHD
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHCCC
DRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNLDESGVVYIGAEVKAGDILVG
CCEEEEEEEHEEEEHHCCCCCHHHHHCCCCCCCHHHHHCCCCCCEEEEECEECCCCEEEE
KVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARA
ECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHH
KSIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EREKWFDIRIEDDAISQQLEQLSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKV
HHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHH
YLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGTAVDIVLNPLGVPSRMNIGQV
HHHHHHHCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
LETHLGLAAKGLGRKIAQMLDEKQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLAD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHH
NLRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNPVTVGYMYMLK
HHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEHHHHHHHH
LNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVK
HHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALGIDIELEHD
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA