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The map label for this gene is trxB

Identifier: 54020431

GI number: 54020431

Start: 319023

End: 319940

Strand: Reverse

Name: trxB

Synonym: mhp281

Alternate gene names: 54020431

Gene position: 319940-319023 (Counterclockwise)

Preceding gene: 54020432

Following gene: 54020430

Centisome position: 35.84

GC content: 35.62

Gene sequence:

>918_bases
ATGGAAAATTATGATGTAATAATTATTGGTGCAGGTCCTGCGGGTCTGACAACCGCCCTTTATGCCTCTCGCGGCAATTT
GAAAGTGTTAATTCTGGAAAAAGGTGCCCCAGGTGGAAAATTAGTCTCCCAGTCAAAAATAGAAAATTGACCAGGAGATG
AGATAATTGATGGTGCAACATTAGCGCTTAGAATGTATAAACATCCTTTAAAATTCGGCGCAAAACACCGCTTTTGCGAT
GTCGATTTTATCGAAACTGAAAATGAATTTGACCATAAAGTTTATTGTAAAGACGGAAAAATTTTTCAAGGCCGAGCAGT
TGTAGTTGCTTCAGGGATGGTCGAAAGAAAACCGCTTGATATAAAATATTACCTTGAATATGAGGGAAGGGGTGTTTCAT
ATTGCGTTGTCTGCGATGGTCCTTTTTATGCAAATCAACCTGCAATTGTAATAGGTGGTGGGAATTCTGCTGTTGAAGAA
GGTAGTTTTTTGGCTTCAATTGCCTCAAAAGTTTATATTTTGGTTCGTGATAGCCAATTTAATGCTGAGCCAATGTTGAT
TGAGGATCTCAAAAAAAATAAAAATGTCGAAATTTGGTTTAATGCAAAAGTTTTAGAACTTAGGGGAAAAGATCAGTTAG
AATCTGCTCTAATTGATCATAATGGTGAGAAAAAAGTACTTGAAATTAAGTCACTTTTTCCTTATATTGGGTTTTTACCA
GCTACAAAATTTTTAGAAAAAAACCATAGGCAAGCATTAAATCAAATTAATTTTATTGATGTTGATTCTTATGGTCAGAC
AAAAATCCCCGGAATTTATGCTGTCGGAGATGTGGTTAGCAAAGAAATTCGCCAAATTGTAACGGCAGCAAGTGATGGTG
CTATAGTTGGGAAAATTTTAACTAACCGAATTAAATAA

Upstream 100 bases:

>100_bases
AAAAAATTTTCTACTATAGTAATTTTTTCCGATTTTTAGAATAAAAATATTATAATTTGTATATAATTTATTATAATATT
TTTATGAAAGGTGCTTTGCT

Downstream 100 bases:

>100_bases
AAATTAAAAAAGGGGCAGTAAGGTTGTGAAGATTGTTAAGAAAATAAAAAAAACAAAATATTTAACTAGAAAGTCAAAAA
TTTTGTTAGGCCTAGGACTA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MENYDVIIIGAGPAGLTTALYASRGNLKVLILEKGAPGGKLVSQSKIENWPGDEIIDGATLALRMYKHPLKFGAKHRFCD
VDFIETENEFDHKVYCKDGKIFQGRAVVVASGMVERKPLDIKYYLEYEGRGVSYCVVCDGPFYANQPAIVIGGGNSAVEE
GSFLASIASKVYILVRDSQFNAEPMLIEDLKKNKNVEIWFNAKVLELRGKDQLESALIDHNGEKKVLEIKSLFPYIGFLP
ATKFLEKNHRQALNQINFIDVDSYGQTKIPGIYAVGDVVSKEIRQIVTAASDGAIVGKILTNRIK

Sequences:

>Translated_305_residues
MENYDVIIIGAGPAGLTTALYASRGNLKVLILEKGAPGGKLVSQSKIEN*PGDEIIDGATLALRMYKHPLKFGAKHRFCD
VDFIETENEFDHKVYCKDGKIFQGRAVVVASGMVERKPLDIKYYLEYEGRGVSYCVVCDGPFYANQPAIVIGGGNSAVEE
GSFLASIASKVYILVRDSQFNAEPMLIEDLKKNKNVEIWFNAKVLELRGKDQLESALIDHNGEKKVLEIKSLFPYIGFLP
ATKFLEKNHRQALNQINFIDVDSYGQTKIPGIYAVGDVVSKEIRQIVTAASDGAIVGKILTNRIK
>Mature_305_residues
MENYDVIIIGAGPAGLTTALYASRGNLKVLILEKGAPGGKLVSQSKIEN*PGDEIIDGATLALRMYKHPLKFGAKHRFCD
VDFIETENEFDHKVYCKDGKIFQGRAVVVASGMVERKPLDIKYYLEYEGRGVSYCVVCDGPFYANQPAIVIGGGNSAVEE
GSFLASIASKVYILVRDSQFNAEPMLIEDLKKNKNVEIWFNAKVLELRGKDQLESALIDHNGEKKVLEIKSLFPYIGFLP
ATKFLEKNHRQALNQINFIDVDSYGQTKIPGIYAVGDVVSKEIRQIVTAASDGAIVGKILTNRIK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=305, Percent_Identity=35.0819672131148, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=29.8701298701299, Blast_Score=115, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=34.8101265822785, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=32.6984126984127, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33518; Mature: 33518

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYDVIIIGAGPAGLTTALYASRGNLKVLILEKGAPGGKLVSQSKIENPGDEIIDGATL
CCCCEEEEEECCCCCHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHH
ALRMYKHPLKFGAKHRFCDVDFIETENEFDHKVYCKDGKIFQGRAVVVASGMVERKPLDI
HHHHHHHHHHCCCCCCEECEEEEECCCCCCCEEEECCCCEEECCEEEEECCCCCCCCCCE
KYYLEYEGRGVSYCVVCDGPFYANQPAIVIGGGNSAVEEGSFLASIASKVYILVRDSQFN
EEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCCC
AEPMLIEDLKKNKNVEIWFNAKVLELRGKDQLESALIDHNGEKKVLEIKSLFPYIGFLPA
CCCHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
TKFLEKNHRQALNQINFIDVDSYGQTKIPGIYAVGDVVSKEIRQIVTAASDGAIVGKILT
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEHHHHH
NRIK
HCCC
>Mature Secondary Structure
MENYDVIIIGAGPAGLTTALYASRGNLKVLILEKGAPGGKLVSQSKIENPGDEIIDGATL
CCCCEEEEEECCCCCHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHH
ALRMYKHPLKFGAKHRFCDVDFIETENEFDHKVYCKDGKIFQGRAVVVASGMVERKPLDI
HHHHHHHHHHCCCCCCEECEEEEECCCCCCCEEEECCCCEEECCEEEEECCCCCCCCCCE
KYYLEYEGRGVSYCVVCDGPFYANQPAIVIGGGNSAVEEGSFLASIASKVYILVRDSQFN
EEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCCC
AEPMLIEDLKKNKNVEIWFNAKVLELRGKDQLESALIDHNGEKKVLEIKSLFPYIGFLPA
CCCHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHH
TKFLEKNHRQALNQINFIDVDSYGQTKIPGIYAVGDVVSKEIRQIVTAASDGAIVGKILT
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEHHHHH
NRIK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]