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The map label for this gene is ppa

Identifier: 54020268

GI number: 54020268

Start: 777692

End: 778249

Strand: Direct

Name: ppa

Synonym: mhp622

Alternate gene names: 54020268

Gene position: 777692-778249 (Clockwise)

Preceding gene: 54020267

Following gene: 54020269

Centisome position: 87.11

GC content: 26.34

Gene sequence:

>558_bases
ATGGAAAATAAAATAATTTTAGTTGATATTGAGATAAGTAAAGGTTCAAATATAAAATATGAACTTGATTCTAAAACAAA
AAAATTAGTAGTTGATCGAATTTTATATGGTGATTTTGTCTACCCAGCAAATTATGGTAGTATTCCAAAAACTTTAGATT
GAGATGGCGATGCTCTTGATTTTTTAGTCTATTCAAATCAAAAATTTCTACCAGGAACCCAATTAAATGCAAGACTTTTA
GGGGCTCTTGAAATGATTGATGATGGTGAAATTGATACAAAATTAATTGGTGTCCATAATGATGACTACCGTTTTGATCA
TATAAAATCTCTTGATGATCTACCGCAGGAATGACTTGATTCGATTTATTATTTTTTTAGCAACTACAAAAATTGAAAAA
GACCCGGAATTACTAAAGTTTCAAAATTTCTCAAATATGATCAAGCATTAAAAGAATATAAAACTTGCCAAGAATTATTT
AATAAATATAAGGACTTTAAAAAATCTGAATTTTTAAAATTAATGATGGAGCAATTTCCTGAAAAATATCAAAAATAA

Upstream 100 bases:

>100_bases
TTATTCGTTTAGTTATTTTTATAACAAGAATTATGGCTTCAAGGTATTAGAAAAAATAATCTAAAAAACTTATTTTTAAA
GGATATTTTATAAAATATAA

Downstream 100 bases:

>100_bases
TTTCAGAAAAATTTGAATTTTTGTAAAAACCAAATAAATTTTAAATTTTATTTGGTTTTTTTCTTTTTAACGAAATTATT
TTTGTAAATAATAAATTTTT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MENKIILVDIEISKGSNIKYELDSKTKKLVVDRILYGDFVYPANYGSIPKTLDWDGDALDFLVYSNQKFLPGTQLNARLL
GALEMIDDGEIDTKLIGVHNDDYRFDHIKSLDDLPQEWLDSIYYFFSNYKNWKRPGITKVSKFLKYDQALKEYKTCQELF
NKYKDFKKSEFLKLMMEQFPEKYQK

Sequences:

>Translated_185_residues
MENKIILVDIEISKGSNIKYELDSKTKKLVVDRILYGDFVYPANYGSIPKTLD*DGDALDFLVYSNQKFLPGTQLNARLL
GALEMIDDGEIDTKLIGVHNDDYRFDHIKSLDDLPQE*LDSIYYFFSNYKN*KRPGITKVSKFLKYDQALKEYKTCQELF
NKYKDFKKSEFLKLMMEQFPEKYQK
>Mature_185_residues
MENKIILVDIEISKGSNIKYELDSKTKKLVVDRILYGDFVYPANYGSIPKTLD*DGDALDFLVYSNQKFLPGTQLNARLL
GALEMIDDGEIDTKLIGVHNDDYRFDHIKSLDDLPQE*LDSIYYFFSNYKN*KRPGITKVSKFLKYDQALKEYKTCQELF
NKYKDFKKSEFLKLMMEQFPEKYQK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=133, Percent_Identity=39.8496240601504, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21309; Mature: 21309

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKIILVDIEISKGSNIKYELDSKTKKLVVDRILYGDFVYPANYGSIPKTLDDGDALDF
CCCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCEEE
LVYSNQKFLPGTQLNARLLGALEMIDDGEIDTKLIGVHNDDYRFDHIKSLDDLPQELDSI
EEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
YYFFSNYKNKRPGITKVSKFLKYDQALKEYKTCQELFNKYKDFKKSEFLKLMMEQFPEKY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QK
CC
>Mature Secondary Structure
MENKIILVDIEISKGSNIKYELDSKTKKLVVDRILYGDFVYPANYGSIPKTLDDGDALDF
CCCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCEEE
LVYSNQKFLPGTQLNARLLGALEMIDDGEIDTKLIGVHNDDYRFDHIKSLDDLPQELDSI
EEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
YYFFSNYKNKRPGITKVSKFLKYDQALKEYKTCQELFNKYKDFKKSEFLKLMMEQFPEKY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]