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The map label for this gene is rnhB

Identifier: 54020259

GI number: 54020259

Start: 766317

End: 767063

Strand: Direct

Name: rnhB

Synonym: mhp613

Alternate gene names: 54020259

Gene position: 766317-767063 (Clockwise)

Preceding gene: 54020258

Following gene: 54020260

Centisome position: 85.84

GC content: 25.84

Gene sequence:

>747_bases
ATGATCTTGTCTAAAAACCAATTATATGCTCTAGATGACTTAGTTATTGGTTGTGATGAAGTTGGAGTTGGTGAATATTT
TACAAATTTAACTGTATGTTGTGCAGTTTTTCGTGAAAAAGAGATTGAAAATGAACTTTTAATACAAATAGTTGATTCAA
AACTTTTAACAGAAAAGAAAATTTCTGATCTTTTTCAGGTTATAAACACAGACCAAAAAATAAAACATAAATTTACCAGT
CTTGAAATGAATGAGTATAATAAACTTATTGAAAATGGACTAAATTCACATCAAATTAAGTCACTTTTGTATTTTCGAGT
TTTAAATGATTTGATTTTGAATCTTGAAAATGAAAAAATTAATAAAATTTTTATTGATGGATTTGTAAGTGAAAAAAAGT
TTAAGGAATATTTTGCAAAAATAGCGGAATTTTTAAAAATTGAACCTTGAGATTTTCAAAAATTCCCGCTAATCTTAGAA
AAAAAAGCTGATACAAAAATTAAGCAAGTAGGCGCAGCCTCAATAATTGCAAAATTTGCCTTAAGTCAAAAATTTGCTAA
AAGGCAAGAGAAATGAAAGGCTGTTTTTCCTGCTGGTTCCAATCAGATTGAAAAAATTGTTAATTTTTGTGTTGGTCAAA
TTGAAAAATATGGCAAAATTTTTCTTGAAGAAAATGTTAAACTTCATTTTAGTATCACTGAAAAAATTTATGCAAAGTTA
GAGGAAAAAAATGGGAAAAATAATTAA

Upstream 100 bases:

>100_bases
AAAAAATACCCTGTTTTCATTCTTAATTTTGTTGAATGGAAGCTAAATAAGCAAAAAATAATGACCAAAATTAAAGAAAA
AATTCTTACTTTGAAAGAAG

Downstream 100 bases:

>100_bases
ATTATTCGCTGAAAGCACTGAAAAAATCGCCACAAATATCAATGTTGCTGGCGGAGTTGGTCTTGGTGGCTGAATCGGAA
TTACAATTTCGGTTGGAATT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MILSKNQLYALDDLVIGCDEVGVGEYFTNLTVCCAVFREKEIENELLIQIVDSKLLTEKKISDLFQVINTDQKIKHKFTS
LEMNEYNKLIENGLNSHQIKSLLYFRVLNDLILNLENEKINKIFIDGFVSEKKFKEYFAKIAEFLKIEPWDFQKFPLILE
KKADTKIKQVGAASIIAKFALSQKFAKRQEKWKAVFPAGSNQIEKIVNFCVGQIEKYGKIFLEENVKLHFSITEKIYAKL
EEKNGKNN

Sequences:

>Translated_248_residues
MILSKNQLYALDDLVIGCDEVGVGEYFTNLTVCCAVFREKEIENELLIQIVDSKLLTEKKISDLFQVINTDQKIKHKFTS
LEMNEYNKLIENGLNSHQIKSLLYFRVLNDLILNLENEKINKIFIDGFVSEKKFKEYFAKIAEFLKIEP*DFQKFPLILE
KKADTKIKQVGAASIIAKFALSQKFAKRQEK*KAVFPAGSNQIEKIVNFCVGQIEKYGKIFLEENVKLHFSITEKIYAKL
EEKNGKNN
>Mature_248_residues
MILSKNQLYALDDLVIGCDEVGVGEYFTNLTVCCAVFREKEIENELLIQIVDSKLLTEKKISDLFQVINTDQKIKHKFTS
LEMNEYNKLIENGLNSHQIKSLLYFRVLNDLILNLENEKINKIFIDGFVSEKKFKEYFAKIAEFLKIEP*DFQKFPLILE
KKADTKIKQVGAASIIAKFALSQKFAKRQEK*KAVFPAGSNQIEKIVNFCVGQIEKYGKIFLEENVKLHFSITEKIYAKL
EEKNGKNN

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 28380; Mature: 28380

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSKNQLYALDDLVIGCDEVGVGEYFTNLTVCCAVFREKEIENELLIQIVDSKLLTEKK
CCCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDLFQVINTDQKIKHKFTSLEMNEYNKLIENGLNSHQIKSLLYFRVLNDLILNLENEKI
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
NKIFIDGFVSEKKFKEYFAKIAEFLKIEPDFQKFPLILEKKADTKIKQVGAASIIAKFAL
HEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHH
SQKFAKRQEKKAVFPAGSNQIEKIVNFCVGQIEKYGKIFLEENVKLHFSITEKIYAKLEE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHH
KNGKNN
CCCCCC
>Mature Secondary Structure
MILSKNQLYALDDLVIGCDEVGVGEYFTNLTVCCAVFREKEIENELLIQIVDSKLLTEKK
CCCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDLFQVINTDQKIKHKFTSLEMNEYNKLIENGLNSHQIKSLLYFRVLNDLILNLENEKI
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
NKIFIDGFVSEKKFKEYFAKIAEFLKIEPDFQKFPLILEKKADTKIKQVGAASIIAKFAL
HEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHH
SQKFAKRQEKKAVFPAGSNQIEKIVNFCVGQIEKYGKIFLEENVKLHFSITEKIYAKLEE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHH
KNGKNN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA