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The map label for this gene is xylH [H]

Identifier: 54020225

GI number: 54020225

Start: 645720

End: 646970

Strand: Direct

Name: xylH [H]

Synonym: mhp513

Alternate gene names: 54020225

Gene position: 645720-646970 (Clockwise)

Preceding gene: 54020224

Following gene: 54020226

Centisome position: 72.33

GC content: 32.05

Gene sequence:

>1251_bases
ATGGAATTTTTTAATAATTTAAAAAATAATTTAAAAGATTTTGCAAAACCAGTTAAAAATTATCTAAATGAGACAAAAAG
TGGACATTATCTTCAAGCCAGCCTCCACCATCTAAAAAAATTTTCAATGTTATATATTTTTCTTCTGGTTTTTGTTATTT
TTTTAGGGATTACCAAAGGAACTTTATTACAAGCAAATACATTCACCCTTTTATTTCAAAATAATTCTTATATTATTATT
TTGGCAATGGGGATGCTACTTGTAATTTTAAGTGGAAATATTGATCTTTCTGTTGGAACTCTTGTCGGTCTTTTAGGACT
ATTTTCGGTTTATATTTATAATAATACCGGCCAAAGTATTTGACTAACTTTTATACTTACAACGCTAATCGGGGCCGCAA
TTGGTTTTATCCAAGGCTGACTTATTGGTTATGGAAATATCCCGGCATTTATTGTAACTTTAGGTGGATTTCTTGCTTTT
AAAGGGGCTCAACTTGTCTATTCAAATGGGGCAACACTGACTCCAATTGGATCTGTTGGATCAACTTATATTAAAGGAAC
AATTGAAGGAATCCCTGATCTAAAAGTAGGGAATATTTGAATTTTTTCTTTACTTTTACCTCTAATTTTAGGCGCAATTA
TTGTTAGTCTGCGAACTTGAGGATATTATACAAAAAGAAAATTTGGCATTAAAGTTCAAAATATTATTATTTTTACAATA
ATTCAAGTAATTATTTTTTCTTTATTCCTTGCTTGTGGTATAATATTTTCACTTGGAGATAAATCAATGCGTTACTATGT
TTTATATGTAGGTATCGCACTGGCTTTATTTACTTTTCTTAGCCAAAATACCGCTTTTGGGCGCTCTGTTTATGCAATTG
GTGGCAACCGGAAAGCTGCTCTATTATCCGGGGTTAATGTTAAAAGAACAACAATGATAATTTTTATTATCATTGGCGCA
CTAGCCGGATTTTCTTCGATTATTTTCACAGCTACTTATTCTTCTGCGACTTCTTCGCGAGGTGATGATCTTGCTCTTGA
TGTCATTTCAGTTGTCTTTACTGGTGGAGCTTCAGTCTATGGTGGAATTGGATCGGTTAGTGGAACGATATTAGGAACAT
CAATTATCGGGGTAATCAACCAAGGTTTGCTTGTTCTAAATGTTGCCGAATCACAAAAATACATAATTAAAGGACTAATT
TTAGTTGCTGTTGTTGGATGAGATGTTCTCTCAAATAAGAAAAATAACTAA

Upstream 100 bases:

>100_bases
GAATTTTTGTCATGTCCCAGGGAATTATCAAAGGTCAGATAAAAACTTCTGAGGCAAATCAAGAAAAAATTATGCAACTA
AGTATTGGGGGTCTTATCTA

Downstream 100 bases:

>100_bases
AAAAATCTTTAAAACAAAAGAAAATAAGTCAAATTTTTCCTTTTGTTTTGCTTGTGAAAAACAACAGATCCATTTTTTCA
ATGAAATTTTTATTGAAAAA

Product: xylose ABC transporter permease protein

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MEFFNNLKNNLKDFAKPVKNYLNETKSGHYLQASLHHLKKFSMLYIFLLVFVIFLGITKGTLLQANTFTLLFQNNSYIII
LAMGMLLVILSGNIDLSVGTLVGLLGLFSVYIYNNTGQSIWLTFILTTLIGAAIGFIQGWLIGYGNIPAFIVTLGGFLAF
KGAQLVYSNGATLTPIGSVGSTYIKGTIEGIPDLKVGNIWIFSLLLPLILGAIIVSLRTWGYYTKRKFGIKVQNIIIFTI
IQVIIFSLFLACGIIFSLGDKSMRYYVLYVGIALALFTFLSQNTAFGRSVYAIGGNRKAALLSGVNVKRTTMIIFIIIGA
LAGFSSIIFTATYSSATSSRGDDLALDVISVVFTGGASVYGGIGSVSGTILGTSIIGVINQGLLVLNVAESQKYIIKGLI
LVAVVGWDVLSNKKNN

Sequences:

>Translated_416_residues
MEFFNNLKNNLKDFAKPVKNYLNETKSGHYLQASLHHLKKFSMLYIFLLVFVIFLGITKGTLLQANTFTLLFQNNSYIII
LAMGMLLVILSGNIDLSVGTLVGLLGLFSVYIYNNTGQSI*LTFILTTLIGAAIGFIQG*LIGYGNIPAFIVTLGGFLAF
KGAQLVYSNGATLTPIGSVGSTYIKGTIEGIPDLKVGNI*IFSLLLPLILGAIIVSLRT*GYYTKRKFGIKVQNIIIFTI
IQVIIFSLFLACGIIFSLGDKSMRYYVLYVGIALALFTFLSQNTAFGRSVYAIGGNRKAALLSGVNVKRTTMIIFIIIGA
LAGFSSIIFTATYSSATSSRGDDLALDVISVVFTGGASVYGGIGSVSGTILGTSIIGVINQGLLVLNVAESQKYIIKGLI
LVAVVG*DVLSNKKNN
>Mature_416_residues
MEFFNNLKNNLKDFAKPVKNYLNETKSGHYLQASLHHLKKFSMLYIFLLVFVIFLGITKGTLLQANTFTLLFQNNSYIII
LAMGMLLVILSGNIDLSVGTLVGLLGLFSVYIYNNTGQSI*LTFILTTLIGAAIGFIQG*LIGYGNIPAFIVTLGGFLAF
KGAQLVYSNGATLTPIGSVGSTYIKGTIEGIPDLKVGNI*IFSLLLPLILGAIIVSLRT*GYYTKRKFGIKVQNIIIFTI
IQVIIFSLFLACGIIFSLGDKSMRYYVLYVGIALALFTFLSQNTAFGRSVYAIGGNRKAALLSGVNVKRTTMIIFIIIGA
LAGFSSIIFTATYSSATSSRGDDLALDVISVVFTGGASVYGGIGSVSGTILGTSIIGVINQGLLVLNVAESQKYIIKGLI
LVAVVG*DVLSNKKNN

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=407, Percent_Identity=29.97542997543, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788896, Length=142, Percent_Identity=40.1408450704225, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790191, Length=149, Percent_Identity=38.9261744966443, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693152, Length=133, Percent_Identity=38.3458646616541, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790524, Length=142, Percent_Identity=37.3239436619718, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787793, Length=341, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787794, Length=372, Percent_Identity=25.2688172043011, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082395, Length=102, Percent_Identity=38.2352941176471, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788471, Length=160, Percent_Identity=36.875, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43925; Mature: 43925

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFNNLKNNLKDFAKPVKNYLNETKSGHYLQASLHHLKKFSMLYIFLLVFVIFLGITKG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLLQANTFTLLFQNNSYIIILAMGMLLVILSGNIDLSVGTLVGLLGLFSVYIYNNTGQSI
CEEEECEEEEEEECCCEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHEEEECCCCHHH
LTFILTTLIGAAIGFIQGLIGYGNIPAFIVTLGGFLAFKGAQLVYSNGATLTPIGSVGST
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCEECCCCCCCCH
YIKGTIEGIPDLKVGNIIFSLLLPLILGAIIVSLRTGYYTKRKFGIKVQNIIIFTIIQVI
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCHHHHHHHHHHHHH
IFSLFLACGIIFSLGDKSMRYYVLYVGIALALFTFLSQNTAFGRSVYAIGGNRKAALLSG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEC
VNVKRTTMIIFIIIGALAGFSSIIFTATYSSATSSRGDDLALDVISVVFTGGASVYGGIG
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCC
SVSGTILGTSIIGVINQGLLVLNVAESQKYIIKGLILVAVVGDVLSNKKNN
CCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEFFNNLKNNLKDFAKPVKNYLNETKSGHYLQASLHHLKKFSMLYIFLLVFVIFLGITKG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLLQANTFTLLFQNNSYIIILAMGMLLVILSGNIDLSVGTLVGLLGLFSVYIYNNTGQSI
CEEEECEEEEEEECCCEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHEEEECCCCHHH
LTFILTTLIGAAIGFIQGLIGYGNIPAFIVTLGGFLAFKGAQLVYSNGATLTPIGSVGST
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCEECCCCCCCCH
YIKGTIEGIPDLKVGNIIFSLLLPLILGAIIVSLRTGYYTKRKFGIKVQNIIIFTIIQVI
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCHHHHHHHHHHHHH
IFSLFLACGIIFSLGDKSMRYYVLYVGIALALFTFLSQNTAFGRSVYAIGGNRKAALLSG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEC
VNVKRTTMIIFIIIGALAGFSSIIFTATYSSATSSRGDDLALDVISVVFTGGASVYGGIG
CCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCC
SVSGTILGTSIIGVINQGLLVLNVAESQKYIIKGLILVAVVGDVLSNKKNN
CCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]