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The map label for this gene is ruvB

Identifier: 54020198

GI number: 54020198

Start: 499930

End: 500886

Strand: Direct

Name: ruvB

Synonym: mhp422

Alternate gene names: 54020198

Gene position: 499930-500886 (Clockwise)

Preceding gene: 161936257

Following gene: 54020199

Centisome position: 56.0

GC content: 31.56

Gene sequence:

>957_bases
ATGCCAGAGAATTTAGAAATTAGACCAAGCAGTTTTGAAAATTTTATCGGGCAAAAAAAATTAGTTGAAACCTTACAAAT
TTTAATTAGCTCATCACAAAAACGGAAGCAATCACTTGATCATATTCTCTTTTATGGACCACCAGGAACAGGAAAAACGA
CACTAGCTAACATCGTTGCAAATGTTCTTGAGGCTAAAATTAAATATGTTCAGGGTCCTTTGCTTGAAAAAAAGTCAGAT
GTGCTTGCAGTTTTAGCAAATATTTCGCCGGATACCATCATTTTTATCGATGAAATTCACGGAATTAATAAAAATATTGA
AGAACTTTTATATTCAGCAATGGAAGAATTTGTAATTGATCTTCAGATTGGCGTTGATGGGGAGAGAAAAATTATGCGGA
TGAAACTCCCGCAATTTACACTAATTGGCGCTTCAACTAAACTTGCTCAAATTTCAACGCCATTACAAAACCGTTTTGGT
TATGTTGCTAAAATAGTTGATTATACACTTGAAGATATGATCCAGATTATTCGGAATTCCTCAGCAGTTTTAAAACTTAA
AATGAATACCGAAATTATTAAATATATTGCAAGTTTTTCCAATAATACACCAAGAATTGCCAATAATTTATTAAAAAGAA
TTCGTGATTTCGCGCTAGTTTTAAATGCAAAACGAATTGACAAAGACATTGTTAATAAAACTTTTGATAGTATTGGAATT
TATAATCAAGGTCTTTCGCAGATAAATATTGAATATTTAAACCTCCTTGTAAAAATTTTTAAGGGAAAATCAGTGGCACT
TGATGTAATTGCAAATGTTTTAAAAGAACATCGGCAAACCATTATCAATATTATTGAGCCGCCATTAATTGAGAAGGAAT
TAATCGAGAAAACCTCGCGTGGTCGGAGGATTACTAAAAAAGGTAGGGATTATTTACTCGAACTAAAAACTAATTAA

Upstream 100 bases:

>100_bases
CTTGGTTTCAAACCACGGCAAATTGATTATGCGCTTACAAAAGTTGAACCTAATGAAAATTTTGAAAATTTAATTGAAAA
CGCAATTAAAATTATATCAA

Downstream 100 bases:

>100_bases
GTTACTTTTTTAGCTTTAATTCTCAAAAAGTGTAACTTTTTGGGGTTTGATTACCTTAATATTAGACGCATTATTTGCAT
TTTTATAAATAAATTTGAGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVANVLEAKIKYVQGPLLEKKSD
VLAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVIDLQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFG
YVAKIVDYTLEDMIQIIRNSSAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGI
YNQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSRGRRITKKGRDYLLELKTN

Sequences:

>Translated_318_residues
MPENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVANVLEAKIKYVQGPLLEKKSD
VLAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVIDLQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFG
YVAKIVDYTLEDMIQIIRNSSAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGI
YNQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSRGRRITKKGRDYLLELKTN
>Mature_317_residues
PENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVANVLEAKIKYVQGPLLEKKSDV
LAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVIDLQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFGY
VAKIVDYTLEDMIQIIRNSSAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGIY
NQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSRGRRITKKGRDYLLELKTN

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=315, Percent_Identity=37.1428571428571, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_MYCH2 (Q600N3)

Other databases:

- EMBL:   AE017332
- RefSeq:   YP_115932.1
- ProteinModelPortal:   Q600N3
- SMR:   Q600N3
- STRING:   Q600N3
- GeneID:   3105475
- GenomeReviews:   AE017332_GR
- KEGG:   mhy:mhp422
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   MHYO295358:MHP422-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00819
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36063; Mature: 35932

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCHHHHHHHHH
NVLEAKIKYVQGPLLEKKSDVLAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVID
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEE
LQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFGYVAKIVDYTLEDMIQIIRNS
EEECCCCCHHHHHHCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGI
CEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
YNQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSR
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GRRITKKGRDYLLELKTN
CCCHHHCCCCEEEEEECC
>Mature Secondary Structure 
PENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCHHHHHHHHH
NVLEAKIKYVQGPLLEKKSDVLAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVID
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEE
LQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFGYVAKIVDYTLEDMIQIIRNS
EEECCCCCHHHHHHCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGI
CEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
YNQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSR
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GRRITKKGRDYLLELKTN
CCCHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA