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The map label for this gene is asnC

Identifier: 54020192

GI number: 54020192

Start: 493490

End: 494839

Strand: Direct

Name: asnC

Synonym: mhp416

Alternate gene names: 54020192

Gene position: 493490-494839 (Clockwise)

Preceding gene: 54020191

Following gene: 54020193

Centisome position: 55.28

GC content: 32.37

Gene sequence:

>1350_bases
ATGTTCCAAACTATTAACGAAATTTCCATTCATCCTGAATTATATAACCAAAAAAAGGTTCTAATTCAGGGCTGGATAAC
TAACATTCGCGGGAATTTAAAAATTATATTTGTTGAATTAAATGATGGTTCTTCATTTAAAAATTTACAATGTGTATTAA
AAAAAGAGTTTATTGACTTTGATAAAATAGAAAATTTAGCCCTCGGTGTTGCAGTTGAAATTTCCGGAATTTTTTCAAAT
ACACCTGAACGTCAACAATTTGGCGAAGTTTTAGTTGAGACTTTGGAAATTAAAGGTAATAATTATAACACAAATTTTCC
GATTCAAAATCAGGAAATTTCCCTTGAGGTTCTCCGCCAAATGCCTCACTTTCGCCATCGAAGTCGTTTATTTCGTGTTA
TTATGAAACTAAGATCAGCGCTATTTTTTGAAATTCATAAATTTTTTCGCAGGCAAGGATTTATTAATTTTTCAGCCCCA
ATTCTAACCTCAAATGATGGCGAAGGAGCTGGTGAAGTTTTTATCGTTGATGATGAAAATAAAGATTTTTTTAATAAAAA
AACGACCTTAGGTGTAACCGGACAACTTCATGCTGAAGCTTATGCTCTTGGTTTTAAAAAAGTTTATACATTTGCCCCAA
CATTTCGGGCTGAGCGTTCAAATACGAGAAGGCATGCTGCCGAATTTTGGATGATTGAACCCGAAGTGGCCTTTTTTACT
TTAGAACAAATTATCGAATTAGCAGTTAAATTACTTCAAAAAGTAATAAAATCAGTAATAATTCGCAACAAAGATGAGTT
TATTTTTCTAGAAAAAGCCGGGGATAAAAATCTCCGAAAGCGTTTGCTTCAATTTTGTGATTCTCAAGTTACTCAAATAA
GTTATGAAAAGGCGATTGAATTGCTTTTAGAACATCAAGAAAAATTCGAGGAAAAAGATTTATTTTTTGGCTGTGATCTA
AAAACCGAACATGAACGGTTTTTAACCGAAGAAATTTTTCATATGCCTGTTGTAATTATAAATTATCCTAAAAATTTAAA
AGCTTTTTATATGCATCAAAACGAAGATGGTCAAACTGTAGCAGCCTTTGATTTATTGGTTCCGGGAATTGGGGAGTTAA
TTGGGGGCTCACAACGCGAAGTTCGCTATGAAAAATTATTAGCGCGGATGAATGAATTGAATATGAATATTGAAGAATTT
CAGTGATATTTAGATCTTAGAAAGTATGGCAATCCTGGATCAAGTGGTTTTGGGCTTGGTTTTGAACGACTTTTAATGTA
TATTACAGGAATTGAAAATATTCGTGATGTAATTCCCTTTCCGCGGACAAATAAAAATATTCTAATGTAA

Upstream 100 bases:

>100_bases
AAATGTTTTAATTTTAACTTATTTTTATTTTAATTATAGTAAAAAAACCTAAATTTTATGATATAATAAAAGAGTTTTTA
TAATAATATGGGGTGAAAAT

Downstream 100 bases:

>100_bases
AACAGGGAGAAAATTGAATAATAATTCTGAAAAAGCACAGTTTTGACGTCGATTTCTAGCTGGCTTAATTGATTTTATCC
TGCTTTTTGCTTTGTTTTTA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDFDKIENLALGVAVEISGIFSN
TPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQMPHFRHRSRLFRVIMKLRSALFFEIHKFFRRQGFINFSAP
ILTSNDGEGAGEVFIVDDENKDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFT
LEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIELLLEHQEKFEEKDLFFGCDL
KTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTVAAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEF
QWYLDLRKYGNPGSSGFGLGFERLLMYITGIENIRDVIPFPRTNKNILM

Sequences:

>Translated_449_residues
MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDFDKIENLALGVAVEISGIFSN
TPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQMPHFRHRSRLFRVIMKLRSALFFEIHKFFRRQGFINFSAP
ILTSNDGEGAGEVFIVDDENKDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFT
LEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIELLLEHQEKFEEKDLFFGCDL
KTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTVAAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEF
Q*YLDLRKYGNPGSSGFGLGFERLLMYITGIENIRDVIPFPRTNKNILM
>Mature_449_residues
MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDFDKIENLALGVAVEISGIFSN
TPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQMPHFRHRSRLFRVIMKLRSALFFEIHKFFRRQGFINFSAP
ILTSNDGEGAGEVFIVDDENKDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFT
LEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIELLLEHQEKFEEKDLFFGCDL
KTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTVAAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEF
Q*YLDLRKYGNPGSSGFGLGFERLLMYITGIENIRDVIPFPRTNKNILM

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=441, Percent_Identity=40.5895691609977, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI4758762, Length=443, Percent_Identity=28.8939051918736, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI45439306, Length=328, Percent_Identity=25.3048780487805, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1787161, Length=448, Percent_Identity=43.0803571428571, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1788173, Length=205, Percent_Identity=27.3170731707317, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556372, Length=414, Percent_Identity=33.8164251207729, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=439, Percent_Identity=27.1070615034169, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17551876, Length=328, Percent_Identity=29.2682926829268, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319872, Length=463, Percent_Identity=36.9330453563715, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6321807, Length=439, Percent_Identity=29.1571753986333, Blast_Score=180, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6323011, Length=337, Percent_Identity=25.2225519287834, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19922416, Length=449, Percent_Identity=32.0712694877506, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI19921528, Length=431, Percent_Identity=27.3781902552204, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17136276, Length=340, Percent_Identity=27.0588235294118, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52152; Mature: 52152

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDF
CCCCCCCEEECHHHHCCCCEEEEHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCH
DKIENLALGVAVEISGIFSNTPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQ
HHHHHHHEEEEEEEEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHC
MPHFRHRSRLFRVIMKLRSALFFEIHKFFRRQGFINFSAPILTSNDGEGAGEVFIVDDEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCEEEEEECCC
KDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFT
CCHHCCCCEEEECCCHHHHHHHHHHHHHHEECCCHHCCCCCCHHHHHHEEEECCCHHHHH
LEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEHQEKFEEKDLFFGCDLKTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTV
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCEE
AAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEFQYLDLRKYGNPGSSGFGLGF
EEHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCH
ERLLMYITGIENIRDVIPFPRTNKNILM
HHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFQTINEISIHPELYNQKKVLIQGWITNIRGNLKIIFVELNDGSSFKNLQCVLKKEFIDF
CCCCCCCEEECHHHHCCCCEEEEHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCH
DKIENLALGVAVEISGIFSNTPERQQFGEVLVETLEIKGNNYNTNFPIQNQEISLEVLRQ
HHHHHHHEEEEEEEEEHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHC
MPHFRHRSRLFRVIMKLRSALFFEIHKFFRRQGFINFSAPILTSNDGEGAGEVFIVDDEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCEEEEEECCC
KDFFNKKTTLGVTGQLHAEAYALGFKKVYTFAPTFRAERSNTRRHAAEFWMIEPEVAFFT
CCHHCCCCEEEECCCHHHHHHHHHHHHHHEECCCHHCCCCCCHHHHHHEEEECCCHHHHH
LEQIIELAVKLLQKVIKSVIIRNKDEFIFLEKAGDKNLRKRLLQFCDSQVTQISYEKAIE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLLEHQEKFEEKDLFFGCDLKTEHERFLTEEIFHMPVVIINYPKNLKAFYMHQNEDGQTV
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCEE
AAFDLLVPGIGELIGGSQREVRYEKLLARMNELNMNIEEFQYLDLRKYGNPGSSGFGLGF
EEHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCH
ERLLMYITGIENIRDVIPFPRTNKNILM
HHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA