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The map label for this gene is rsmH

Identifier: 54020186

GI number: 54020186

Start: 483354

End: 484244

Strand: Direct

Name: rsmH

Synonym: mhp406

Alternate gene names: 54020186

Gene position: 483354-484244 (Clockwise)

Preceding gene: 54020185

Following gene: 54020187

Centisome position: 54.14

GC content: 31.87

Gene sequence:

>891_bases
ATGCATGTTCCAGTTTTGTTAGAGGAACTTATTTTAGCCCTGGAAATTAACCCAAAAGGATTTTATGTTGATTTAACTTT
AGGACGCGGCGGACATTCCTTAGCGATTCTTGAAAAAATTAGTAATGGAAAATTGGTTGTTTTTGATAAAGACCAGGATG
CCTTAGATCAAACAAGACCAAAATTATTGGCACTTAAGCAAAACATTGAAATTATTTGGTCAGATTTTTCCAGATTTGAT
TTCTATCTTGAAAATTTAGGAATTCAATTTGTTGATGGATTTATCATCGATTTAGGGGTCTCATCTCCGCAGATTGATGA
TCCCGCGCGGGGATTTTCATATTCTAAAGATGGCAATTTAGATATGCGAATGGATAAGAGTCAAAAACTTAGTGCTTTTA
TTGTTCTTAATGAATATCCCTATGAAAAATTAGTTGAAATTTTCTTTAAATATGGCCAGATTCCATATGCACGCGAAATT
GCCAGAGCAATTATTAACTCTCGCCCTTTGAAGACTACTTTTGAGCTGGTAAATCTTGTAAAAAAAGTAATTCCTGCGCT
GGTGTTAGTTAAAAAAAATTTTATAAAAAATGTTTTTCAGGCTGTTCGGATTGAAGTTAATAATGAACTTGATTCCTTGC
AAAAGTTGTTAGAAAAGTTACCAAAATTTTTAAAGCAAGGATCAAAAGTAGCAATTATTACCTTTCATTCGTTAGAGGAT
CGAATCGTTAAAAAAGCATTTTTGGATCTAATTAGAAAAGACAAACTGGAATTTTTTCAAAAAGGTTTACCAAAATTTTC
TATGAAAGTTTTCCGACCAAAAGCTAATGAATTAAAGTCAAATCCGCGAGCAAAATCAGCAAAATTACGACTTCTTTTAC
AAAATAGATAA

Upstream 100 bases:

>100_bases
CCAGAACAAAGATACGAACAATTTTATGCAAAATTTTCTGATAGCGAAATGACCGCTGATCTTGAAAAAGAGTTGCTAAA
ATCGGGAGTTGAATTATAAA

Downstream 100 bases:

>100_bases
AAATTGGAACCAAAAAAAGGTAGAAATACTATGGAAAAATGTAGTAAAATTATGCTAATGGGATTAGGTGATTTTGGATC
AAAAATTGTTGAGTCAATCA

Product: hypothetical protein

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MHVPVLLEELILALEINPKGFYVDLTLGRGGHSLAILEKISNGKLVVFDKDQDALDQTRPKLLALKQNIEIIWSDFSRFD
FYLENLGIQFVDGFIIDLGVSSPQIDDPARGFSYSKDGNLDMRMDKSQKLSAFIVLNEYPYEKLVEIFFKYGQIPYAREI
ARAIINSRPLKTTFELVNLVKKVIPALVLVKKNFIKNVFQAVRIEVNNELDSLQKLLEKLPKFLKQGSKVAIITFHSLED
RIVKKAFLDLIRKDKLEFFQKGLPKFSMKVFRPKANELKSNPRAKSAKLRLLLQNR

Sequences:

>Translated_296_residues
MHVPVLLEELILALEINPKGFYVDLTLGRGGHSLAILEKISNGKLVVFDKDQDALDQTRPKLLALKQNIEIIWSDFSRFD
FYLENLGIQFVDGFIIDLGVSSPQIDDPARGFSYSKDGNLDMRMDKSQKLSAFIVLNEYPYEKLVEIFFKYGQIPYAREI
ARAIINSRPLKTTFELVNLVKKVIPALVLVKKNFIKNVFQAVRIEVNNELDSLQKLLEKLPKFLKQGSKVAIITFHSLED
RIVKKAFLDLIRKDKLEFFQKGLPKFSMKVFRPKANELKSNPRAKSAKLRLLLQNR
>Mature_296_residues
MHVPVLLEELILALEINPKGFYVDLTLGRGGHSLAILEKISNGKLVVFDKDQDALDQTRPKLLALKQNIEIIWSDFSRFD
FYLENLGIQFVDGFIIDLGVSSPQIDDPARGFSYSKDGNLDMRMDKSQKLSAFIVLNEYPYEKLVEIFFKYGQIPYAREI
ARAIINSRPLKTTFELVNLVKKVIPALVLVKKNFIKNVFQAVRIEVNNELDSLQKLLEKLPKFLKQGSKVAIITFHSLED
RIVKKAFLDLIRKDKLEFFQKGLPKFSMKVFRPKANELKSNPRAKSAKLRLLLQNR

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=33.7278106508876, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI165377202, Length=196, Percent_Identity=35.2040816326531, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=37.3801916932907, Blast_Score=179, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472493, Length=330, Percent_Identity=32.1212121212121, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571637, Length=330, Percent_Identity=32.1212121212121, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_MYCH2 (Q600P9)

Other databases:

- EMBL:   AE017332
- RefSeq:   YP_115916.1
- ProteinModelPortal:   Q600P9
- SMR:   Q600P9
- STRING:   Q600P9
- GeneID:   3105430
- GenomeReviews:   AE017332_GR
- KEGG:   mhy:mhp406
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   CLSK741316
- BioCyc:   MHYO295358:MHP406-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34041; Mature: 34041

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: BINDING 49-49 BINDING 76-76 BINDING 97-97 BINDING 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVPVLLEELILALEINPKGFYVDLTLGRGGHSLAILEKISNGKLVVFDKDQDALDQTRP
CCCHHHHHHHHHHEEECCCEEEEEEEECCCCCEEHEEEECCCCEEEEEECCCHHHHHHCH
KLLALKQNIEIIWSDFSRFDFYLENLGIQFVDGFIIDLGVSSPQIDDPARGFSYSKDGNL
HHHHHHCCCCEEEHHHHHHHHHHHHCCHHEECCEEEEECCCCCCCCCCCCCCCCCCCCCE
DMRMDKSQKLSAFIVLNEYPYEKLVEIFFKYGQIPYAREIARAIINSRPLKTTFELVNLV
EEEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
KKVIPALVLVKKNFIKNVFQAVRIEVNNELDSLQKLLEKLPKFLKQGSKVAIITFHSLED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
RIVKKAFLDLIRKDKLEFFQKGLPKFSMKVFRPKANELKSNPRAKSAKLRLLLQNR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MHVPVLLEELILALEINPKGFYVDLTLGRGGHSLAILEKISNGKLVVFDKDQDALDQTRP
CCCHHHHHHHHHHEEECCCEEEEEEEECCCCCEEHEEEECCCCEEEEEECCCHHHHHHCH
KLLALKQNIEIIWSDFSRFDFYLENLGIQFVDGFIIDLGVSSPQIDDPARGFSYSKDGNL
HHHHHHCCCCEEEHHHHHHHHHHHHCCHHEECCEEEEECCCCCCCCCCCCCCCCCCCCCE
DMRMDKSQKLSAFIVLNEYPYEKLVEIFFKYGQIPYAREIARAIINSRPLKTTFELVNLV
EEEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
KKVIPALVLVKKNFIKNVFQAVRIEVNNELDSLQKLLEKLPKFLKQGSKVAIITFHSLED
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
RIVKKAFLDLIRKDKLEFFQKGLPKFSMKVFRPKANELKSNPRAKSAKLRLLLQNR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA