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The map label for this gene is mraY

Identifier: 52842823

GI number: 52842823

Start: 2953702

End: 2954820

Strand: Reverse

Name: mraY

Synonym: lpg2617

Alternate gene names: 52842823

Gene position: 2954820-2953702 (Counterclockwise)

Preceding gene: 52842824

Following gene: 52842822

Centisome position: 86.96

GC content: 41.02

Gene sequence:

>1119_bases
TTGAGCATAATTTTAAGAACAAGAGGAATAATTATGCTCTATTGGTTAACGCAGTTATTGCAGGGACAATATCATGCGTT
TAGAGTTTTTCAATATTTGACATTCAGGTCTATTTTAGCCTCATTAACTGCCCTTATAGTGGGTTTGTTATGTGGCCCAT
TAATGATCCGCTGGTTAAGAGGGCTGCAAATAGGTCAAATGGTTAGGAGTGATGGCCCCCAAACCCATTTATCAAAGGCG
GGAACTCCCACTATGGGGGGCGTTTTGATTTTATTGGCTATCACTGTGAGTTGCTTGCTCTGGTGCGATTTAAGACAAAC
AAGCCTGTGGCTGGTGCTCTTGGTTACCTTGGCTAATGGTTTGGTTGGTTGGGTTGATGATTATCGCAAGTTGGTATTAA
AAAATAGCAAAGGATTACCTGGTCGTTGGAAATATTTTTGGCAGTCAGTCATTGCTTTAGTTGCTGTCTCTTATTTGTAT
TGGAATGCCAGTTTGCCAGTACATACTCAGCTCACAGTTCCTTTTTTTAAAACGGTCACTTGGGATCTGGGCGTTTTTTT
TCCTGTACTTGCCTATTTCGTCATTGTTGGAAGCAGTAATGCAGTGAATTTAACTGATGGGCTGGATGGCTTGGCTATTA
TGCCAATAGTAATGGTGGCTGGTGCCTTGGGTGTGTTTGCCTATGCATCGAGTAACGCCGTATACTCTAATTATTTAGGA
ATTCCTTATGTGCCCAATACTGGTGAGCTAACGATTTTTTGTTCTTCTATTGTTGGTGCCGGCCTGGGTTTTCTTTGGTA
TAACAGTTATCCTGCCCAAGTTTTCATGGGCGATGTGGGCTCTTTGGCGTTAGGAGCAGCTTTAGGGATAGTTGCGGTTG
TAGTTAGACAAGAACTTGTTTTGCTCATTATGGGTGGATTATTTGTAATTGAGACGCTTTCTGTCATATTACAAGTGGGT
TATTTTAAATATTCAGGCGGAAAAAGATTATTCAGGATGGCCCCATTACATCACCATTTTGAATTAAAGGGGTGGTCAGA
GCCCAAAGTGATAGTAAGGTTTTGGATTATTACGGTTGTATTTGTGTTATGCGGATTGGCTACTTTAAAACTTCGATAG

Upstream 100 bases:

>100_bases
GGTTCAGGTAGAGGGCTAACCTCTTCATTGAATCGACAGGAATGTGGTATGCTTGGCCACTTTTTTGCCCCATTAAAGGA
ATCATGCTCAATAAAAGTCA

Downstream 100 bases:

>100_bases
ACAAGGTGCATTCATGAATCATTCCTTATATTTGGTAGCAGGGCTGGGTAAGACGGGACTCTCTATAGCAAGATACCTGA
AGAGAAATAATAAATCGTTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSIILRTRGIIMLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKA
GTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLY
WNASLPVHTQLTVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLG
IPYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVG
YFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Sequences:

>Translated_372_residues
MSIILRTRGIIMLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKA
GTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLY
WNASLPVHTQLTVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLG
IPYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVG
YFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR
>Mature_371_residues
SIILRTRGIIMLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAG
TPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYW
NASLPVHTQLTVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGI
PYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVGY
FKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=61.7728531855956, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 41110; Mature: 40978

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILRTRGIIMLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLR
CEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQIGQMVRSDGPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANG
CCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTVPFFKTVT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
WDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLG
HHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
IPYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELV
CCCCCCCCCEEEEHHHHHHCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
LLIMGGLFVIETLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVV
HHHHHHHHHHHHHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHH
FVLCGLATLKLR
HHHHCHHHHCCC
>Mature Secondary Structure 
SIILRTRGIIMLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLR
EEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQIGQMVRSDGPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANG
CCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTVPFFKTVT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
WDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLG
HHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
IPYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELV
CCCCCCCCCEEEEHHHHHHCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
LLIMGGLFVIETLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVV
HHHHHHHHHHHHHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHH
FVLCGLATLKLR
HHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA