| Definition | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome. |
|---|---|
| Accession | NC_002942 |
| Length | 3,397,754 |
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The map label for this gene is dacB
Identifier: 52842795
GI number: 52842795
Start: 2921870
End: 2923663
Strand: Reverse
Name: dacB
Synonym: lpg2589
Alternate gene names: 52842795
Gene position: 2923663-2921870 (Counterclockwise)
Preceding gene: 52842796
Following gene: 52842794
Centisome position: 86.05
GC content: 43.53
Gene sequence:
>1794_bases ATGAAAAGGACGTTGACTGGGGCATTCATGTGGGCAGTATGGTCACTGTCATCTCATGCGGCTAGTATGCAGTTCGAGGT GGATAAATTAATTAATCGGCTAAACCCTCATGTGAACCTGGGGATAGTAGTGACCGATCTAACCTCGGGCGAGACGCTAT ATAAACGCAATGCCAATCGTTTGTATATTCCTGCCAGCAACATGAAGCTTTTTTCCGAGGCAGCGGCTCTGATGGCTTTG GGTCCAGACTACCAATTCAAGAATCAACTCAGTACGAGCGCCAATCAATTACAACAAGGTGTTTTGCACGGAAACTTGTA TTTACATCTCAGCGGCGATCCTTCGTTTAGCAGAGAAGATTTAAAGACGTTGCTTTCTTCACTCAAGGATTGGAATATCA CAACCATTCAAGGTAATGTGATCATTGACAGTAGCCTGATGTCCATTCCTGCCTATCCCCCAGGCTGGCTAACTTCGGAT TTATCTTATAGTTATGGTGCGCCAATAGCACCTTTGATGGTTGATTCCAACCGATTAACAATCACGGTCAACCCCGGGGC TAAAGCAGGCGCTCCTGCTATTGTTGAAGTAGATGATGGCGGCGGTACCATTAACCTGAATAATCAAGCGACCACGAAGG CGAGTGAGAAAGGATGTGGTGTAGGGTTTTATTTGGATCCTGAGAACAATTTAACGGTAAGAGGCTGTGTTGGATTAGGG CAATGGGCTGTTCAGCAACGCATCGCTATAAAGAATCCTTTTGTTTATGCCCAGGGGATGATTGTGAGTGAGCTTGCCAA GTCTAACATTAAATTAAATGGGCAGGTTTTGCTTGGAAGAGCTCCTGCTGGTACTTTATTAATTGCCACTCGCTATTCAA AGCCAATTTCCCAACTGATGGCAGATACTTTAAAGCCTTCTGATAATTTATATGCTGATAGTTTATACTTGCATGCTGCT GCCAAAATTAAGGGTAGTCCTGTGGATTGGAAGCAAGCACAGCCAGTAATTAAAAACTTTTTGCAGCAACAAACAGGAAT CGATTTAAAAGACTCGAATTTTACAGATGGTTCTGGATTATCACGTTATAATTTGGTAACTCCAGCGCAAACCATGGCGC TTTTAAAGTTCTTGTATCAACGTTTCCCATTATCATACGAATACATTGCTGCTTTACCCATCTCTGGTCGGGATGGTACT TTGCAAAAACGGTTTAAAACCCCAAATCAACAAGGATTTGTGCGAGCCAAAACCGGGACGATGACGGGGATGAACAGTTT ATCCGGTTACTTGTATACTGCTAATGGCCATACTTTGGCTTTTGCTATGTATATCAATAGATTACCAGGAAAACCAGCTG GGCCAGGACGTCCATTATTAGACGCATTATGCACTTATTTCTTGCAGCAAAGCCCAACAAGCAGTCGACTGGCACGGGTA TTATCTCCCCACAGTCGCATTAAGTTCCAATTTAATCCTACACAAATTGAGTTACAGCGAGTTCATCAAGCCAAATGGAG GCGTTTGGAAACGGCAGTGAGGCAGGTCTTGAGAGGACAGGATGTGAATGTGGTTTACCGGGGCAATGAATTAATCGTGA CAGACAATCAGTCTAATGCGAATAGCGTTTGGAAAGCTTTACAATCAATTGGCAAGAAATATTCATTCGCCGTAGCTTTG TCTTCTAAAGTGATGCCTGTTACACCATCGGGAAAACCTTTGCTTCTTTGGGTGCAAGCACCTTTATCTGAAAATAAGGC AGAGAGAACCTGGATAATTCGGGAAGCGGTATAA
Upstream 100 bases:
>100_bases TATGATTAGCTTATTGGAACTAACTCAGAAATTGTCACTATGTATCAAACAATTCAACCTGATTTATATTGTGAAATTCA ATGTTAAGGAAAATATTTAA
Downstream 100 bases:
>100_bases TCTGAGTTTGATAATTAAAAGAAAGACTAGCCTCATATTACAAAATGTAATGCGGGGCTCTTCCAACGTAACGTTATCTT GAGTCGTTTGGGCTGAGGAG
Product: D-alanyl-D-alanine carboxypeptidase, fraction B; penicillin binding protein 4
Products: NA
Alternate protein names: DD-carboxypeptidase; DD-peptidase; D-alanyl-D-alanine endopeptidase; DD-endopeptidase; Penicillin-binding protein 4; PBP-4 [H]
Number of amino acids: Translated: 597; Mature: 597
Protein sequence:
>597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV
Sequences:
>Translated_597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV >Mature_597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV
Specific function: Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction [H]
COG id: COG2027
COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S13 family [H]
Homologues:
Organism=Escherichia coli, GI1789573, Length=438, Percent_Identity=30.1369863013699, Blast_Score=212, Evalue=4e-56,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR000667 [H]
Pfam domain/function: PF02113 Peptidase_S13 [H]
EC number: =3.4.16.4 [H]
Molecular weight: Translated: 65573; Mature: 65573
Theoretical pI: Translated: 10.20; Mature: 10.20
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANR CCCCHHHHHHHHHHHHHCCHHHEEEEHHHHHHHCCCCEEEEEEEEECCCCCCCEECCCCE LYIPASNMKLFSEAAALMALGPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSRED EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECEEEEEECCCCCCCHHH LKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSDLSYSYGAPIAPLMVDSNRLT HHHHHHHHCCCCEEEEECCEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE ITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLM HHHHHHHHHHCCCEEEECCHHHHHHHHCCCEECCEEEEECCCCCEEEEEECCCHHHHHHH ADTLKPSDNLYADSLYLHAAAKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGL HHHCCCCCCEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC SRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGTLQKRFKTPNQQGFVRAKTGT CEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECCC MTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV CCCHHHCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNA HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCH NSVWKALQSIGKKYSFAVALSSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV HHHHHHHHHHCCCEEEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECC >Mature Secondary Structure MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANR CCCCHHHHHHHHHHHHHCCHHHEEEEHHHHHHHCCCCEEEEEEEEECCCCCCCEECCCCE LYIPASNMKLFSEAAALMALGPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSRED EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECEEEEEECCCCCCCHHH LKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSDLSYSYGAPIAPLMVDSNRLT HHHHHHHHCCCCEEEEECCEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE ITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLM HHHHHHHHHHCCCEEEECCHHHHHHHHCCCEECCEEEEECCCCCEEEEEECCCHHHHHHH ADTLKPSDNLYADSLYLHAAAKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGL HHHCCCCCCEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC SRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGTLQKRFKTPNQQGFVRAKTGT CEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECCC MTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV CCCHHHCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNA HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCH NSVWKALQSIGKKYSFAVALSSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV HHHHHHHHHHCCCEEEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2040429; 9278503; 2046551 [H]