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The map label for this gene is ampC [C]

Identifier: 52841352

GI number: 52841352

Start: 1226336

End: 1227451

Strand: Reverse

Name: ampC [C]

Synonym: lpg1118

Alternate gene names: 52841352

Gene position: 1227451-1226336 (Counterclockwise)

Preceding gene: 52841354

Following gene: 52841351

Centisome position: 36.13

GC content: 36.56

Gene sequence:

>1116_bases
ATGAGCCGTTATGTATGCAAGTGGAAATTGATTTATACGTTTTTCATTTTTATTGTCTTTAATAATTGCCCACTTGCCTT
TGCGAGCCCTTCCTTAACCAAGCAATTACATACCATATTAAAAGACAATCTCGCAGACTCATTAACCCCTGGAGCAGTAT
TACTGATATCAAGTGCTGATTTAGGCACAATTTCCGTCGCGGCAGGGTTGGCAGATAAGGAAAATGATATTTCAATGAAT
ATTACGGACAGTTTTCGTCTTGCAAGCATGAGTAAAACATTTTTGGCTGTAACTGTCTTAAAACTGGTAGCAGATAAACA
GTTAAATCTTGATGATCATATTGCAGACTTATTGCCAGATAGTATAGATATTGAACGTATACCGAATGGAGATGAGGTAA
CAGTGCAACAATTACTACAAATGCGTAGCGGCATTCCTAATTATACGGATTATGATTCTTACAGTGATCTCATTGATACT
ATGGCAGACAAGGAATGGACACCAGAAGAATGCATTAAACTAGTCTACGATCAAAAACCTGACTTTAAGCCAGGAACAGC
TTATGAGTACAGCAATACTAATTATTTGTTGCTGCAATTAATTATCGAAAACATAACCGGAGAATCCTATGCCGAATCAA
TTAAGAAATACATCCTGAAACCTCTTCATTTAAAAAATACATATATAGAAAAGCAAGAATTTGATGACGACCATCATTAT
TTATCAACACATGGCTATACCTTGGAAGATGGCAAAGTGGTTGACGTAACAGACCATGATGATGGTTTTGGCTTGGCTGA
TGGTGGAATAATTAGTACTGCTGAAGATATTAATATCTTTGTCCAGGCGTTGTTGAAAGATAAAATACTTTTATCTCCAA
ACTATTTAACAATGATGCTTACCTTTACAGATGATTACGGTTTTGGAATAGGACGTGAAGAAATTAATGGAGAGATAGCC
TGGTCCCATAATGGGGCAAGCTCAGGATACCAAGGCCAGTACTACTATTTTCCAGACCGGCAATTGACTGTTGTTATTTT
AACCAACTATTTTGACAGTGATATCATCGAAGACATAGTATCTCAGACTCTCAGTGCGATTGACAATTCTGAATAA

Upstream 100 bases:

>100_bases
CTATTTTATACAGGAAGTAAAGAAATTATCCTGAAATCGACTAGAATTAAGATATAGCTCATTTGGTGGGTGAGAAAACC
CTTGCCACATTGGAGTTGCA

Downstream 100 bases:

>100_bases
CTGCTTAGCTGCACTCATCTAATGGAAGCCCGCAAAATAGATTATATGTTATACTAAGTGAAAATTATCTAGGCTTTTAT
GGGGGCAAAATATGGCTATT

Product: serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSADLGTISVAAGLADKENDISMN
ITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDT
MADKEWTPEECIKLVYDQKPDFKPGTAYEYSNTNYLLLQLIIENITGESYAESIKKYILKPLHLKNTYIEKQEFDDDHHY
LSTHGYTLEDGKVVDVTDHDDGFGLADGGIISTAEDINIFVQALLKDKILLSPNYLTMMLTFTDDYGFGIGREEINGEIA
WSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIVSQTLSAIDNSE

Sequences:

>Translated_371_residues
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSADLGTISVAAGLADKENDISMN
ITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDT
MADKEWTPEECIKLVYDQKPDFKPGTAYEYSNTNYLLLQLIIENITGESYAESIKKYILKPLHLKNTYIEKQEFDDDHHY
LSTHGYTLEDGKVVDVTDHDDGFGLADGGIISTAEDINIFVQALLKDKILLSPNYLTMMLTFTDDYGFGIGREEINGEIA
WSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIVSQTLSAIDNSE
>Mature_370_residues
SRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSADLGTISVAAGLADKENDISMNI
TDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTM
ADKEWTPEECIKLVYDQKPDFKPGTAYEYSNTNYLLLQLIIENITGESYAESIKKYILKPLHLKNTYIEKQEFDDDHHYL
STHGYTLEDGKVVDVTDHDDGFGLADGGIISTAEDINIFVQALLKDKILLSPNYLTMMLTFTDDYGFGIGREEINGEIAW
SHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIVSQTLSAIDNSE

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41734; Mature: 41603

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSAD
CCCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LGTISVAAGLADKENDISMNITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPD
CCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTMADKEWTPEECIKLVYDQKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DFKPGTAYEYSNTNYLLLQLIIENITGESYAESIKKYILKPLHLKNTYIEKQEFDDDHHY
CCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCE
LSTHGYTLEDGKVVDVTDHDDGFGLADGGIISTAEDINIFVQALLKDKILLSPNYLTMML
EECCCEEECCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCEEEEEE
TFTDDYGFGIGREEINGEIAWSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIV
EEECCCCCCCCHHHCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHH
SQTLSAIDNSE
HHHHHHHCCCC
>Mature Secondary Structure 
SRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSAD
CCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LGTISVAAGLADKENDISMNITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPD
CCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTMADKEWTPEECIKLVYDQKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DFKPGTAYEYSNTNYLLLQLIIENITGESYAESIKKYILKPLHLKNTYIEKQEFDDDHHY
CCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCE
LSTHGYTLEDGKVVDVTDHDDGFGLADGGIISTAEDINIFVQALLKDKILLSPNYLTMML
EECCCEEECCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCEEEEEE
TFTDDYGFGIGREEINGEIAWSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIV
EEECCCCCCCCHHHCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHH
SQTLSAIDNSE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]