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The map label for this gene is spoIIIJ [H]

Identifier: 52788049

GI number: 52788049

Start: 4220771

End: 4221568

Strand: Reverse

Name: spoIIIJ [H]

Synonym: BLi04377

Alternate gene names: 52788049

Gene position: 4221568-4220771 (Counterclockwise)

Preceding gene: 52788050

Following gene: 52788048

Centisome position: 99.97

GC content: 44.99

Gene sequence:

>798_bases
TTGTTGAAGAGGCGAATTTTATTATTGTTCAGTATGATCGGCGTTATCGTGCTTTTAGCTGGATGTACGGAAATCAACCA
GCCGATCACTGCAGAAAGCGAAGGGTTTTGGAACACGTATATCGTATACCCGTTGTCACAGCTGATCACGTATGTAGCAA
ATTTAACGAATGAAAACTTCGGACTAGCGATTATCATCGTCACGATCTTAATCAGACTTTTAATTTTGCCGCTGATGATC
AAGCAGACGAAGAGTTCGAAAGCGATGCAGGCTCTCCAGCCTGAAATGCAAAAACTTCGTGAAAAATACAGTTCTAAAGA
TCAAAAAACGCAGCAGAAGCTTCAACAGGAAACGATGGCTCTCATGCAGAAGCACGGGGTTAACCCGCTTGCCGGATGTT
TCCCGATCTTAATTCAAATGCCGATTTTAATCGGATTCTATCATGCCATTATGAGAACGCGGGAAATCGCAGAACACAGC
TTTTTATGGTTTGACCTTGGGGAGCGTGATCCGTATTTCATTTTGCCGATTCTCGCCGGTGTGTTCACATTCATTCAGCA
AAAGCTGATGATGGCGGGAACAGCGCAGCAAAATCCGCAGATGGCGATGATGCTTTGGCTGATGCCGATCATGATCGTTG
TATTTGCGATCAGTTTCCCGGCGGCTCTTTCCCTGTACTGGGTAGTCGGTAACTTATTCATGATTGCTCAAACCTTCTTT
ATCAAAGGGCCTGATCTAAAGGCTGAGAGACAGGAAGCGGCAGCCGGAGGAAAAAAATCCGGAGGTAAGAAAAAGTGA

Upstream 100 bases:

>100_bases
CCATTCGGGGGAGAAAGATGATAAAATACGAGAAAGTATGTCTTTTTAATGGTCATAACCGAATAATACCGGTTGAAGAA
TGAAGATTTAGGAGGAAATG

Downstream 100 bases:

>100_bases
AGGAACTGACTGCTACTGGACGTACCGTCGATGAAGCAGTGCAATCCGGGCTTGAACAGCTGGGCCTTCATGCAGATGAT
GTCGAAGTCGACGTAGTTGA

Product: OxaA-like protein precursor

Products: NA

Alternate protein names: Stage III sporulation protein J [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLKRRILLLFSMIGVIVLLAGCTEINQPITAESEGFWNTYIVYPLSQLITYVANLTNENFGLAIIIVTILIRLLILPLMI
KQTKSSKAMQALQPEMQKLREKYSSKDQKTQQKLQQETMALMQKHGVNPLAGCFPILIQMPILIGFYHAIMRTREIAEHS
FLWFDLGERDPYFILPILAGVFTFIQQKLMMAGTAQQNPQMAMMLWLMPIMIVVFAISFPAALSLYWVVGNLFMIAQTFF
IKGPDLKAERQEAAAGGKKSGGKKK

Sequences:

>Translated_265_residues
MLKRRILLLFSMIGVIVLLAGCTEINQPITAESEGFWNTYIVYPLSQLITYVANLTNENFGLAIIIVTILIRLLILPLMI
KQTKSSKAMQALQPEMQKLREKYSSKDQKTQQKLQQETMALMQKHGVNPLAGCFPILIQMPILIGFYHAIMRTREIAEHS
FLWFDLGERDPYFILPILAGVFTFIQQKLMMAGTAQQNPQMAMMLWLMPIMIVVFAISFPAALSLYWVVGNLFMIAQTFF
IKGPDLKAERQEAAAGGKKSGGKKK
>Mature_265_residues
MLKRRILLLFSMIGVIVLLAGCTEINQPITAESEGFWNTYIVYPLSQLITYVANLTNENFGLAIIIVTILIRLLILPLMI
KQTKSSKAMQALQPEMQKLREKYSSKDQKTQQKLQQETMALMQKHGVNPLAGCFPILIQMPILIGFYHAIMRTREIAEHS
FLWFDLGERDPYFILPILAGVFTFIQQKLMMAGTAQQNPQMAMMLWLMPIMIVVFAISFPAALSLYWVVGNLFMIAQTFF
IKGPDLKAERQEAAAGGKKSGGKKK

Specific function: Membrane protein required for the insertion of membrane proteins into the membrane. Also involved in protein secretion processes. Essential for sporulation by activating spoIIIG/sigG in the prespore. It has an overlapping, through partly distinct, functio

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790140, Length=203, Percent_Identity=39.9014778325123, Blast_Score=144, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321002, Length=188, Percent_Identity=27.1276595744681, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24662345, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356443, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708
- InterPro:   IPR023060 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 30008; Mature: 30008

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRRILLLFSMIGVIVLLAGCTEINQPITAESEGFWNTYIVYPLSQLITYVANLTNENF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLAIIIVTILIRLLILPLMIKQTKSSKAMQALQPEMQKLREKYSSKDQKTQQKLQQETMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LMQKHGVNPLAGCFPILIQMPILIGFYHAIMRTREIAEHSFLWFDLGERDPYFILPILAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEHHHHHHH
VFTFIQQKLMMAGTAQQNPQMAMMLWLMPIMIVVFAISFPAALSLYWVVGNLFMIAQTFF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKGPDLKAERQEAAAGGKKSGGKKK
HCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKRRILLLFSMIGVIVLLAGCTEINQPITAESEGFWNTYIVYPLSQLITYVANLTNENF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLAIIIVTILIRLLILPLMIKQTKSSKAMQALQPEMQKLREKYSSKDQKTQQKLQQETMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LMQKHGVNPLAGCFPILIQMPILIGFYHAIMRTREIAEHSFLWFDLGERDPYFILPILAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEHHHHHHH
VFTFIQQKLMMAGTAQQNPQMAMMLWLMPIMIVVFAISFPAALSLYWVVGNLFMIAQTFF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKGPDLKAERQEAAAGGKKSGGKKK
HCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1487728; 1552862; 7584024; 9384377; 11889108; 12586834; 12813085 [H]