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The map label for this gene is yyaF [H]

Identifier: 52788036

GI number: 52788036

Start: 4208040

End: 4209140

Strand: Reverse

Name: yyaF [H]

Synonym: BLi04364

Alternate gene names: 52788036

Gene position: 4209140-4208040 (Counterclockwise)

Preceding gene: 52788037

Following gene: 52788035

Centisome position: 99.68

GC content: 47.87

Gene sequence:

>1101_bases
ATGGCTTTAACAGCTGGGATTGTTGGTTTGCCTAACGTTGGGAAATCAACCTTATTTAATGCAATTACTCAGGCCGGGGC
AGAATCGGCCAACTACCCGTTTTGTACGATTGATCCAAACGTCGGGATCGTAGAGGTGCCTGATGAGCGTCTGCAAAAGC
TGACAGAACTCGTCAATCCGAAGAAAACCGTTCCTACCGCATTTGAATTCACCGATATCGCAGGCATTGTAAAAGGAGCA
TCAAAAGGAGAAGGGCTCGGAAACAAGTTCCTGTCCCACATCCGCCAAGTAGATGCGATCTGCCATGTTGTCCGCTGTTT
TGCCGATGACAATATCACACACGTGTCCGGGAAAGTAGATCCGATTTCGGATATCGAGACGATTAACCTTGAGCTGATAC
TGGCTGACCTTGAAACCGTGGAAAAGCGGATCGGGCGGGTCGGAAAGATGGCCAAGCAAAAAGATAAAGAAGCCGTGTTT
GAATTTGAGATTTTGACAAAGTTAAAAGAGGCGTTTGAACAGGAAAAGCCGGCCCGCTCTGTCGAGTTCTCCGAAGAGCA
GCAAAAGGTGTTGAAGCAGCTTCATCTGCTGACGACAAAACCTGTCTTATATGTAGCTAATGTCAGCGAAGATGAAGTGG
CTGATCCTTCAGGTAACGAGTACGTTCAGAAGGTCCGGGAATTTGCAGCTGCTGAAAATGCGGAAGTCATCGTCGTCTGC
GCAAAGATTGAGTCCGAAATTGCAGAGCTTGAAGGCGAAGAGAAGGCGATGTTCCTTGAAGAACTCGGCATTGAAGAATC
CGGTCTCGATCAGCTGATTAAAGCGTCCTACTCCCTCCTCGGACTTGCTACTTATTTTACAGCGGGAGAACAGGAAGTCA
GAGCTTGGACATTTAAAAAAGGAATGAAAGCCCCTGAATGTGCGGGCATCATCCATACGGACTTTGAACGCGGATTTATC
CGTGCGGAAACGGTCGCCTACGACGATCTGCTTGAAGCGGGAAGCATGACCGCAGCAAAAGAGGCCGGAAAAGTCCGCCT
TGAAGGGAAAGAATACATTGTTAAAGACGGCGATGTCATTCATTTCCGTTTCAATGTATAA

Upstream 100 bases:

>100_bases
AGTTTTGTCAGCTTGTCTTTTATTGTAATCATCCTTATAATTGTTGCAGGTTTAACATTTACGACTACACACGGATGTTC
ATTATAGAGGAGATGAAACA

Downstream 100 bases:

>100_bases
CGCAGTTGAAATAGGACAAGAGCTTTGATATAATATAAAATTGTGAGTAATAGGATTATTGCTCCTTGCCCAATATAATG
GGCCGCTTAGTCCAAAAGGA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLQKLTELVNPKKTVPTAFEFTDIAGIVKGA
SKGEGLGNKFLSHIRQVDAICHVVRCFADDNITHVSGKVDPISDIETINLELILADLETVEKRIGRVGKMAKQKDKEAVF
EFEILTKLKEAFEQEKPARSVEFSEEQQKVLKQLHLLTTKPVLYVANVSEDEVADPSGNEYVQKVREFAAAENAEVIVVC
AKIESEIAELEGEEKAMFLEELGIEESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKKGMKAPECAGIIHTDFERGFI
RAETVAYDDLLEAGSMTAAKEAGKVRLEGKEYIVKDGDVIHFRFNV

Sequences:

>Translated_366_residues
MALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLQKLTELVNPKKTVPTAFEFTDIAGIVKGA
SKGEGLGNKFLSHIRQVDAICHVVRCFADDNITHVSGKVDPISDIETINLELILADLETVEKRIGRVGKMAKQKDKEAVF
EFEILTKLKEAFEQEKPARSVEFSEEQQKVLKQLHLLTTKPVLYVANVSEDEVADPSGNEYVQKVREFAAAENAEVIVVC
AKIESEIAELEGEEKAMFLEELGIEESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKKGMKAPECAGIIHTDFERGFI
RAETVAYDDLLEAGSMTAAKEAGKVRLEGKEYIVKDGDVIHFRFNV
>Mature_365_residues
ALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLQKLTELVNPKKTVPTAFEFTDIAGIVKGAS
KGEGLGNKFLSHIRQVDAICHVVRCFADDNITHVSGKVDPISDIETINLELILADLETVEKRIGRVGKMAKQKDKEAVFE
FEILTKLKEAFEQEKPARSVEFSEEQQKVLKQLHLLTTKPVLYVANVSEDEVADPSGNEYVQKVREFAAAENAEVIVVCA
KIESEIAELEGEEKAMFLEELGIEESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKKGMKAPECAGIIHTDFERGFIR
AETVAYDDLLEAGSMTAAKEAGKVRLEGKEYIVKDGDVIHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=46.2162162162162, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI58761502, Length=216, Percent_Identity=41.6666666666667, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI24308117, Length=100, Percent_Identity=40, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=56.8306010928962, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1789574, Length=134, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.0765027322404, Blast_Score=310, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI17508313, Length=104, Percent_Identity=34.6153846153846, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=40.3225806451613, Blast_Score=256, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6321773, Length=384, Percent_Identity=36.71875, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=158, Percent_Identity=38.6075949367089, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=42.2343324250681, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=42.2343324250681, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=42.2343324250681, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.8773006134969, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24585318, Length=165, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40246; Mature: 40115

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLQKLTELVNP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTAFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICHVVRCFADDNITHVSGKVD
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PISDIETINLELILADLETVEKRIGRVGKMAKQKDKEAVFEFEILTKLKEAFEQEKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VEFSEEQQKVLKQLHLLTTKPVLYVANVSEDEVADPSGNEYVQKVREFAAAENAEVIVVC
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
AKIESEIAELEGEEKAMFLEELGIEESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKK
EHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GMKAPECAGIIHTDFERGFIRAETVAYDDLLEAGSMTAAKEAGKVRLEGKEYIVKDGDVI
CCCCCCCCCCEECCCCCCCEEHHHHHHHHHHHCCCCHHHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
ALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDERLQKLTELVNP
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
KKTVPTAFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICHVVRCFADDNITHVSGKVD
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PISDIETINLELILADLETVEKRIGRVGKMAKQKDKEAVFEFEILTKLKEAFEQEKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VEFSEEQQKVLKQLHLLTTKPVLYVANVSEDEVADPSGNEYVQKVREFAAAENAEVIVVC
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
AKIESEIAELEGEEKAMFLEELGIEESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKK
EHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GMKAPECAGIIHTDFERGFIRAETVAYDDLLEAGSMTAAKEAGKVRLEGKEYIVKDGDVI
CCCCCCCCCCEECCCCCCCEEHHHHHHHHHHHCCCCHHHHHCCCEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]