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The map label for this gene is yyxA [H]

Identifier: 52788006

GI number: 52788006

Start: 4179921

End: 4181132

Strand: Reverse

Name: yyxA [H]

Synonym: BLi04330

Alternate gene names: 52788006

Gene position: 4181132-4179921 (Counterclockwise)

Preceding gene: 52788007

Following gene: 52788005

Centisome position: 99.02

GC content: 50.25

Gene sequence:

>1212_bases
GTGGAGTTTAATCATGATGAGGAAAAATTCGTTCGGGAAAAGCCGGTGAGAAGTTGGAGAAGCTTTTTGTTTTCAAGCCT
GGTCGGCGCCGTCATCGGCGCTCTTTTAACAGTGTTTGCCTTGCCGTATCTCTCGCAGCAGGGATGGCTGCCGTATAATC
TGCAAGTCATCGAAGCGCGCGGCGGCCAAGGAGCACAGCAGGGCGGGACGGTCCGCAATGTATCCGTCAACGTGAATAAT
GAAGTCACGCAAATGGTCTCTAAGGTTTCTGATTCTGTTGTCGGCGTTATCAACATCCAAAAGACAGGTGTATGGGATGG
TGACAGCGAAGCGGGAACAGGCTCGGGCGTTATTTATAAAAAGGACGGCAACACATCCCACATTGTGACAAACCACCATG
TCATTGAAGGGGCGTCCCAAATAGAAATCAGCCTGAATGACGGAACACGGATTCCGGCAAAACTGATCGGCAGCGATAAG
CTGATGGATCTGGCCGTCCTGCAAGTCAACAGCAACAAAATAAAAGCAGCTGCCGAATTTGGAGATTCTGATAAAGTGAA
GACAGGCGAGCCTGTCATCGCGATTGGAAACCCGCTCGGCCTGCAGTTTTCAGGCTCTGTTACACAAGGAATCATCTCAG
GAACCGAACGCGCTGTGCCGGTCGATTCCAACGGAGACGGACAGCCGGACTGGAACGCCGAAGTACTGCAGACGGATGCT
GCCATTAACCCGGGTAACAGCGGAGGCGGGCTGTTTAATATTGATGGAAAAGTCATCGGCATTAATTCGATGAAAATCGC
TGAATCAGCCGTCGAAGGCATCGGTCTGAGCATTCCGGCCAACCTTGCCATTCCGGTTATCGAAGATTTGGAAACGTACG
GTGAAGTGAGACGGCCGTATCTCGGAATTGAGATGAAATCACTTGGCGATATCGCAAGCTACCACTGGCAGGAAACGCTT
AAACTGCCGAAAAACGTAACATCAGGCGTAGTTGTGATGGGTGTTCAGCCGGTATCTCCTGCAGGCAGAGCCGGTCTGAA
AGAGCTCGATGTCATCGTCGAATTTAACGGTGACCGTGTTTACGATATCGTTGATCTGCGTAAAAAGCTTTACACCAAAA
ACGTCGGCGACAAGGTAAAAATCAAATACCTGCGGGGCGGAAAAGAAAAGACAACAGAAGTAAAGCTGACCCGATCCCAA
TTAGGAAGCTGA

Upstream 100 bases:

>100_bases
CCTCTCGTAGCGGTGTAAATTTTCCTGATTGAATGATTAATCTGCAGGCAGATGATCCACACTATATACATATATCGTTC
CTTGAAAGGATTTGAATATA

Downstream 100 bases:

>100_bases
TAAAGACAGTCTGGCCGGTACGGCCGGGCTGTTTTTTTATTATGAAGCGCCCAACGAATGATCGTCAAAAGGAAAAAATG
TGATTTTTGGAGAGTGAAAT

Product: YyxA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQMVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS

Sequences:

>Translated_403_residues
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQMVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS
>Mature_403_residues
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQMVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=322, Percent_Identity=31.9875776397516, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI22129776, Length=300, Percent_Identity=29, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI24308541, Length=341, Percent_Identity=33.1378299120235, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI7019477, Length=331, Percent_Identity=30.5135951661631, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1789629, Length=287, Percent_Identity=39.3728222996516, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1786356, Length=291, Percent_Identity=36.426116838488, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789630, Length=291, Percent_Identity=35.3951890034364, Blast_Score=132, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646839, Length=327, Percent_Identity=34.2507645259939, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43125; Mature: 43125

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
GGQGAQQGGTVRNVSVNVNNEVTQMVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYK
CCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
KDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDKLMDLAVLQVNSNKIKAAAEF
CCCCCCEEEECCEEECCCEEEEEEECCCCCCCHHHCCCCCEEEEEEEEECCCCEEEEECC
GDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
CCCCCCCCCCCEEEECCCCCEEECCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEECC
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPY
CCCCCCCCCCEEEECCEEEEECCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCE
LGIEMKSLGDIASYHWQETLKLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRV
ECEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCEE
YDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQLGS
EHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHCCC
>Mature Secondary Structure
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
GGQGAQQGGTVRNVSVNVNNEVTQMVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYK
CCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
KDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDKLMDLAVLQVNSNKIKAAAEF
CCCCCCEEEECCEEECCCEEEEEEECCCCCCCHHHCCCCCEEEEEEEEECCCCEEEEECC
GDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
CCCCCCCCCCCEEEECCCCCEEECCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEECC
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPY
CCCCCCCCCCEEEECCEEEEECCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCE
LGIEMKSLGDIASYHWQETLKLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRV
ECEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCEE
YDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQLGS
EHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]