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The map label for this gene is hsdM [C]

Identifier: 52787994

GI number: 52787994

Start: 4169384

End: 4170913

Strand: Reverse

Name: hsdM [C]

Synonym: BLi04318

Alternate gene names: 52787994

Gene position: 4170913-4169384 (Counterclockwise)

Preceding gene: 52787995

Following gene: 52787993

Centisome position: 98.77

GC content: 39.35

Gene sequence:

>1530_bases
ATGAGTGAAAAAGTAACAAAAGACCAAATTAACAGTGTTTTATGGCAAGCGGCCGACACATTTAGAGGAAAGGTCGATTC
CAGTACATACAAGGATTATATACTGACAATGCTGTTCATCAAGTATTTAAGTGATGCTTATAAAGAGCATTTAGAAGAGT
ATACGAAGCGTTATAATGGTGATGAGCAACGTATTCAACGTGCGTTATCAAGGGAACGTTTTGTGTTAGATGAACAGTCT
ACATTTGATTATTTGTATAGCAAACGGAATGATGCAGAAATTGGTGAAATTATTAATAAAGCATTGGAACGTCTGGAAAA
CGAAAACACAGGTAAGTTGAGAGGTGTCTTCCGTAACATTGACTTCAACAGTGAAGCGATTCTTGGGAAGGCAAAAGAAC
GAAATGCAATGCTCCGTTCTTTATTAGAGGATTTTAATAAACTGACATTAAAGCCTTCTGTTGTAGGAAGTGAAGATGTC
ATCGGTGATGCTTATCAATACATGATCGAACGTTTTGCATCTGATGCGGGTAAGAAGGGCGGAGAATTTTACACGCCTTC
TATGGCTTCGGAACTGTTAGCACGTCTTGTTAAACCACAGGAAAATGATAGGGTGTATGATCCGACGTGTGGATCAGGAT
CACTTCTTATTCGTGTAGCAAATCAAGTACCAAATAAGAAAGTAGCTATTTATGGACAAGAAAGAAACGGAGCCACGCAC
TCATTAGCATTAATGAATATGTATTTGCATGGTATAGACGATGCGAAAATTGAATGGGGCGATACGTTAGCAAATCCACT
TCACTTAGAAGATGGAAAGCTAATGAAGTTCCAAGCAATTGTAGCGAATCCACCATTCTCTCTTGATAAGTGGGCGATGG
GCTTTGCGGGAGAAGGAACAAACGACAGCAAGTTTAAAATGGAAGCAAGTTTAGATCCACATAGACGTTTTGAGTGGGGT
GTTCCACCAAGTTCAAAAGGAGATTATGCTTTCGTTCAACACATGCTTTATTCATTAGCGGAAAACGGTCGAATGGCAAC
GATTCTTCCACATGGTGTTCTTTTCCGAGGGGCAAGCGAAGGCAAAATTCGTCAACAAATCATTGAGATGAACTTACTGG
ATGCGGTGATTGGCTTACCAGAAGGTCTGTTTTATGGAACTGGAATCCCTGCTTGTATCCTTGTGTTCAAGAAAAATCGT
ACTCGTAAAGATGTTCTTTTTATTGATGCATCTGCCGAAGGGAACTACGAAAAAGGGAAAAATCAAAATCAGCTAAGAGA
ACAAGACATCGCTAAAATTGTTGACACATATGAAAAGCGTGAAACGATTGATAAATACTCCTATGTTGCCACTTTAGATG
AAATAAAGGAAAACGACTATAACCTAAACATTCCTCGGTACGTTGACACATTTGAAGAAGAAGAGCCAGTGGATATGCAT
GCGGTGAAAGAGAATATCGCAAACATCAAACAAGAGCTACAAGAAGTGGAAGCGGAGATGGAGAAATATTTGAAGGAATT
AGGGCTGTAA

Upstream 100 bases:

>100_bases
AAGAAAAAACACTCTACAATAGATTAATTGAAGAAAAGGAAAAATGGTTTAACGCCATCACAAAGCAAATTGTGCAAGGT
GAAATAAGGGAGGAATTAGA

Downstream 100 bases:

>100_bases
CAAATGTAGTTTTTTCAGTACAAAGGGGGAATTAAGATGTTAGCAAAGGGGGATTTTTATTATGGGGCATTTTTATCACA
GTTGGTAAATAGCGGATTTG

Product: hypothetical protein

Products: NA

Alternate protein names: M.MpnORFDP [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSEKVTKDQINSVLWQAADTFRGKVDSSTYKDYILTMLFIKYLSDAYKEHLEEYTKRYNGDEQRIQRALSRERFVLDEQS
TFDYLYSKRNDAEIGEIINKALERLENENTGKLRGVFRNIDFNSEAILGKAKERNAMLRSLLEDFNKLTLKPSVVGSEDV
IGDAYQYMIERFASDAGKKGGEFYTPSMASELLARLVKPQENDRVYDPTCGSGSLLIRVANQVPNKKVAIYGQERNGATH
SLALMNMYLHGIDDAKIEWGDTLANPLHLEDGKLMKFQAIVANPPFSLDKWAMGFAGEGTNDSKFKMEASLDPHRRFEWG
VPPSSKGDYAFVQHMLYSLAENGRMATILPHGVLFRGASEGKIRQQIIEMNLLDAVIGLPEGLFYGTGIPACILVFKKNR
TRKDVLFIDASAEGNYEKGKNQNQLREQDIAKIVDTYEKRETIDKYSYVATLDEIKENDYNLNIPRYVDTFEEEEPVDMH
AVKENIANIKQELQEVEAEMEKYLKELGL

Sequences:

>Translated_509_residues
MSEKVTKDQINSVLWQAADTFRGKVDSSTYKDYILTMLFIKYLSDAYKEHLEEYTKRYNGDEQRIQRALSRERFVLDEQS
TFDYLYSKRNDAEIGEIINKALERLENENTGKLRGVFRNIDFNSEAILGKAKERNAMLRSLLEDFNKLTLKPSVVGSEDV
IGDAYQYMIERFASDAGKKGGEFYTPSMASELLARLVKPQENDRVYDPTCGSGSLLIRVANQVPNKKVAIYGQERNGATH
SLALMNMYLHGIDDAKIEWGDTLANPLHLEDGKLMKFQAIVANPPFSLDKWAMGFAGEGTNDSKFKMEASLDPHRRFEWG
VPPSSKGDYAFVQHMLYSLAENGRMATILPHGVLFRGASEGKIRQQIIEMNLLDAVIGLPEGLFYGTGIPACILVFKKNR
TRKDVLFIDASAEGNYEKGKNQNQLREQDIAKIVDTYEKRETIDKYSYVATLDEIKENDYNLNIPRYVDTFEEEEPVDMH
AVKENIANIKQELQEVEAEMEKYLKELGL
>Mature_508_residues
SEKVTKDQINSVLWQAADTFRGKVDSSTYKDYILTMLFIKYLSDAYKEHLEEYTKRYNGDEQRIQRALSRERFVLDEQST
FDYLYSKRNDAEIGEIINKALERLENENTGKLRGVFRNIDFNSEAILGKAKERNAMLRSLLEDFNKLTLKPSVVGSEDVI
GDAYQYMIERFASDAGKKGGEFYTPSMASELLARLVKPQENDRVYDPTCGSGSLLIRVANQVPNKKVAIYGQERNGATHS
LALMNMYLHGIDDAKIEWGDTLANPLHLEDGKLMKFQAIVANPPFSLDKWAMGFAGEGTNDSKFKMEASLDPHRRFEWGV
PPSSKGDYAFVQHMLYSLAENGRMATILPHGVLFRGASEGKIRQQIIEMNLLDAVIGLPEGLFYGTGIPACILVFKKNRT
RKDVLFIDASAEGNYEKGKNQNQLREQDIAKIVDTYEKRETIDKYSYVATLDEIKENDYNLNIPRYVDTFEEEEPVDMHA
VKENIANIKQELQEVEAEMEKYLKELGL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=406, Percent_Identity=25.3694581280788, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58049; Mature: 57918

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00092 N6_MTASE ; PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVTKDQINSVLWQAADTFRGKVDSSTYKDYILTMLFIKYLSDAYKEHLEEYTKRYNG
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEQRIQRALSRERFVLDEQSTFDYLYSKRNDAEIGEIINKALERLENENTGKLRGVFRNI
HHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCC
DFNSEAILGKAKERNAMLRSLLEDFNKLTLKPSVVGSEDVIGDAYQYMIERFASDAGKKG
CCCCHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GEFYTPSMASELLARLVKPQENDRVYDPTCGSGSLLIRVANQVPNKKVAIYGQERNGATH
CCEECHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEHHHCCCCEEEEEECCCCCCHH
SLALMNMYLHGIDDAKIEWGDTLANPLHLEDGKLMKFQAIVANPPFSLDKWAMGFAGEGT
HHHHHHHHHHCCCCCCEECCHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCC
NDSKFKMEASLDPHRRFEWGVPPSSKGDYAFVQHMLYSLAENGRMATILPHGVLFRGASE
CCCCEEEECCCCHHHCEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECCCC
GKIRQQIIEMNLLDAVIGLPEGLFYGTGIPACILVFKKNRTRKDVLFIDASAEGNYEKGK
CHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCC
NQNQLREQDIAKIVDTYEKRETIDKYSYVATLDEIKENDYNLNIPRYVDTFEEEEPVDMH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHH
AVKENIANIKQELQEVEAEMEKYLKELGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEKVTKDQINSVLWQAADTFRGKVDSSTYKDYILTMLFIKYLSDAYKEHLEEYTKRYNG
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DEQRIQRALSRERFVLDEQSTFDYLYSKRNDAEIGEIINKALERLENENTGKLRGVFRNI
HHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCC
DFNSEAILGKAKERNAMLRSLLEDFNKLTLKPSVVGSEDVIGDAYQYMIERFASDAGKKG
CCCCHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GEFYTPSMASELLARLVKPQENDRVYDPTCGSGSLLIRVANQVPNKKVAIYGQERNGATH
CCEECHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEHHHCCCCEEEEEECCCCCCHH
SLALMNMYLHGIDDAKIEWGDTLANPLHLEDGKLMKFQAIVANPPFSLDKWAMGFAGEGT
HHHHHHHHHHCCCCCCEECCHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCC
NDSKFKMEASLDPHRRFEWGVPPSSKGDYAFVQHMLYSLAENGRMATILPHGVLFRGASE
CCCCEEEECCCCHHHCEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECCCC
GKIRQQIIEMNLLDAVIGLPEGLFYGTGIPACILVFKKNRTRKDVLFIDASAEGNYEKGK
CHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCC
NQNQLREQDIAKIVDTYEKRETIDKYSYVATLDEIKENDYNLNIPRYVDTFEEEEPVDMH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHH
AVKENIANIKQELQEVEAEMEKYLKELGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]