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The map label for this gene is htpG

Identifier: 52787933

GI number: 52787933

Start: 4095742

End: 4097622

Strand: Reverse

Name: htpG

Synonym: BLi04256

Alternate gene names: 52787933

Gene position: 4097622-4095742 (Counterclockwise)

Preceding gene: 52787935

Following gene: 52787928

Centisome position: 97.04

GC content: 43.81

Gene sequence:

>1881_bases
ATGGCTAAGAGAGAATTCAAAGCAGAATCCAAGCGATTGCTGGACATCATGATCAACTCGATTTATTCCCAAAAGGAAGT
CTTTTTAAGGGAGCTGATATCCAATGCGAGCGATGCCATCGATAAAATCTACTACAAAGCGCTGACAGATGATTCACTGA
CATTTAACAAAGACGATTACTACATAAAAATCTCCGCAGATAAAGAAAACAGAACGCTGACCATTGCGGACACCGGAATC
GGCATGACGAAAGAAGAGCTTGAAGAGCATCTTGGAACGATTGCCAAGAGCGGCTCGCTTGCGTTTAAACAAGAAAACGA
ATTAAAAGACGGGCACGATATTATCGGCCAGTTCGGCGTCGGTTTCTACGCCGCTTTTATGGTTGCGGACACCGTCACCG
TCATTACAAAAGCCCATGGCAGCGATGAAGCGCATCAATGGGAATCAGCCGGAGCCGACGGCTATACAATCGAACCGGCT
GCGAAAGAATCAGCCGGAACCGATGTCATTCTGAAGCTGAAAGAGAATACAGACGATGAAAACTATGATGAATACCTGGA
TGTTCATCGCTTAAAAGCGATCATCAAAACATACTCTGATTTCATCCGCTACCCGATCAAGATGGATGTCGCGGTCAACA
AGCCGAAAGAAGGCGCCGAAAATGAATTTGAAGAAGTCCAGGAAGAACAGACGGTCAACAGCATGGTGCCGATTTGGAGA
AAAAACAAAAGCGAACTGAAAGATGAAGATTATGAGGCGTTTTATAAGGAAAAGCATTACGGTTTTGACAAGCCTCTCGC
GCACATCCATACAAGCGTAGACGGCGCGGTGAGATACCATGCGATTTTATTCATTCCTGAAAATATTCCGTTCAACTACT
ACACGAAGGAATTCGAGAAGGGTCTGGAACTGTATTCGAACGGTGTGCTGATCATGGAAAAGTGTCCGGATCTGCTGCCT
GACCATTTCAGCTTTGTCAAAGGAATGGTTGATTCAGAAGATTTATCGCTCAACATTTCGAGGGAGATGCTCCAGCATGA
CAGGCAGCTGAAGCTGATTGCCAAAAACATCAGCAAAAAAATCAAGAATGAGCTGAAGAGCTTGCTGAAAAATGACAGAG
AAAAATACGAGTCTTTTTATCAATCGTTTGGCAGACAGCTTAAATTCGGGGTATACAATGATTTTGGAGCCCATAAAGAT
CTGTTGAAAGACCTGCTGCTTTTCTATTCATCAAAAGAGAAAAAGCTGGTCACCCTTGAGGAATATGTGTCCAGAATGCC
TGAAGATCAAAAATACATTTATTATGCATCAGGCGACTCGTATGACCGAATAGAAAAGCTTCCTCAAACCGAGCTGGTTT
CGGAAAAAGGGTATGAAATCCTTTATTTCACCGAGGATATCGATGAGTTCGCCATCAAAATGCTGGCGAATTATCAAGAG
AAAGAATTCAAGTCGGTATCAAGCGGCGACCTCGGAATCGAAAACGATGACGAGCAAAACCAATCTGACGGGGATGACAG
CCAATACAAAGACCTGTTTGAAGAGATGAAAAAGACTCTGGATGGAAAAGTGAAAAGCGTGAGGGCGTCAAAACGGCTGA
AGACTCACTCCGTATGCCTTGCCGCTGACGGAGAAGTCACCATCGAGATGGAGAAAATCTTAAACGCAATGCCTGACAAT
CAGCATGTAAAGGCTGATAAAGTATTGGAAATCAATACAAACCACGAAGTCTTCAAAACATTGCAGAATGCTTTTGACAA
CGACAAGGATAAATTCAAACTGTACACCGGCCTCCTGTACAACCAGGCGCTGCTGATAGAAGGCTTGCCAATTGAAGACC
CCGTCGAATTTACGAACGATATATGCAAAGTAATGGCATAA

Upstream 100 bases:

>100_bases
TGCCTTATCAATTGACATCGTGTAGGCAGTGTGTTATTTAATTTGTGAACAGAATCGAACGATATATGTATATCATATGA
GCAAAAGAGGAGAGGGATAG

Downstream 100 bases:

>100_bases
AAATAAAAAAAGATACATCTCAGCTTCTTGCGAGATGTATCTTTTTTTGATGTTAATGCTTCACAACTTCCTGTCCCCGC
ACATTCCAAGTCATCGCAAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MAKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDYYIKISADKENRTLTIADTGI
GMTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGVGFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPA
AKESAGTDVILKLKENTDDENYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWR
KNKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEKGLELYSNGVLIMEKCPDLLP
DHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKKIKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKD
LLKDLLLFYSSKEKKLVTLEEYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQE
KEFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCLAADGEVTIEMEKILNAMPDN
QHVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLYNQALLIEGLPIEDPVEFTNDICKVMA

Sequences:

>Translated_626_residues
MAKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDYYIKISADKENRTLTIADTGI
GMTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGVGFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPA
AKESAGTDVILKLKENTDDENYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWR
KNKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEKGLELYSNGVLIMEKCPDLLP
DHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKKIKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKD
LLKDLLLFYSSKEKKLVTLEEYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQE
KEFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCLAADGEVTIEMEKILNAMPDN
QHVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLYNQALLIEGLPIEDPVEFTNDICKVMA
>Mature_625_residues
AKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDYYIKISADKENRTLTIADTGIG
MTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGVGFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPAA
KESAGTDVILKLKENTDDENYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWRK
NKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEKGLELYSNGVLIMEKCPDLLPD
HFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKKIKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKDL
LKDLLLFYSSKEKKLVTLEEYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQEK
EFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCLAADGEVTIEMEKILNAMPDNQ
HVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLYNQALLIEGLPIEDPVEFTNDICKVMA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI154146191, Length=683, Percent_Identity=37.3352855051244, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=37.8854625550661, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI153792590, Length=683, Percent_Identity=37.3352855051244, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI4507677, Length=676, Percent_Identity=33.4319526627219, Blast_Score=335, Evalue=9e-92,
Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=30.6477093206951, Blast_Score=295, Evalue=9e-80,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=38.801261829653, Blast_Score=412, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17559162, Length=663, Percent_Identity=37.5565610859729, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=34.9702380952381, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI115535205, Length=655, Percent_Identity=33.7404580152672, Blast_Score=302, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI115535167, Length=442, Percent_Identity=38.9140271493213, Blast_Score=258, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6325016, Length=675, Percent_Identity=36.2962962962963, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6323840, Length=671, Percent_Identity=36.2146050670641, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17647529, Length=670, Percent_Identity=37.7611940298507, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21357739, Length=682, Percent_Identity=33.8709677419355, Blast_Score=330, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24586016, Length=636, Percent_Identity=34.1194968553459, Blast_Score=310, Evalue=2e-84,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BACLD (Q65CZ5)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081328.1
- RefSeq:   YP_093762.1
- ProteinModelPortal:   Q65CZ5
- STRING:   Q65CZ5
- EnsemblBacteria:   EBBACT00000055040
- EnsemblBacteria:   EBBACT00000059482
- GeneID:   3030682
- GeneID:   3097973
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04256
- KEGG:   bli:BL00247
- NMPDR:   fig|279010.5.peg.4113
- eggNOG:   COG0326
- GeneTree:   EBGT00050000002152
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   BLIC279010-1:BLI04256-MONOMER
- BioCyc:   BLIC279010:BL00247-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72032; Mature: 71901

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCE
YIKISADKENRTLTIADTGIGMTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGV
EEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHH
GFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPAAKESAGTDVILKLKENTDDE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEECCCCCC
NYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWR
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHC
KNKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEK
CCHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHH
GLELYSNGVLIMEKCPDLLPDHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKK
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHH
IKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKDLLKDLLLFYSSKEKKLVTLE
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHH
EYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQE
HHHHHCCCCCCEEEEECCCCHHHHHHCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCHH
KEFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCL
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCEEE
AADGEVTIEMEKILNAMPDNQHVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLY
EECCCEEEEHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
NQALLIEGLPIEDPVEFTNDICKVMA
CCCCEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCE
YIKISADKENRTLTIADTGIGMTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGV
EEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHH
GFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPAAKESAGTDVILKLKENTDDE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCEEEEEEECCCCCC
NYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWR
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHC
KNKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEK
CCHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHH
GLELYSNGVLIMEKCPDLLPDHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKK
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHH
IKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKDLLKDLLLFYSSKEKKLVTLE
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHH
EYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQE
HHHHHCCCCCCEEEEECCCCHHHHHHCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCHH
KEFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCL
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCEEE
AADGEVTIEMEKILNAMPDNQHVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLY
EECCCEEEEHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
NQALLIEGLPIEDPVEFTNDICKVMA
CCCCEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA