BacMap

Definition	Bacillus licheniformis ATCC 14580, complete genome.
Accession	NC_006322
Length	4,222,645

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The map label for this gene is srlD [H]

Identifier: 52787542

GI number: 52787542

Start: 3690830

End: 3691615

Strand: Reverse

Name: srlD [H]

Synonym: BLi03863

Alternate gene names: 52787542

Gene position: 3691615-3690830 (Counterclockwise)

Preceding gene: 52787543

Following gene: 52787541

Centisome position: 87.42

GC content: 49.11

Gene sequence:

>786_bases
ATGGAGATGAATAAAGGAAAAGTGGCATTGATATGCGGCGGCGGCCAAAGTCTCGGAGAAGCGCTGTCCTACCGGATGGC
AGAGGCGGGATATGACATCGCGGTCGCAGACATCAACGGCGAGAACGCCGAAAGGACGGCAGATCATGCAGCCGGTCAAT
ACGGGGTCAAATCGCTGTGGATTCAAGCGGATTTTACAAAGGAAGCCGATGTGAAAAAAATGATCGGCAGGGTCACGGAC
GAATTCAATAAAATCGATGTGATGGTGTACAGTGCGGGAATCGCCAAAAGCAATAAAATCACGGATTTTGAACTTGAAGA
CTGGGAACGGACCATCGAGGTCAATTTGACCGGGTATTTTCTTTGCGCGAGGGAAACGTCAAAGGTCATGATTGAGCAGG
GAAGCGGGTCAATCATTCAAATCAATTCCAAATCGGGAAAAGTCGGCAGCAAGCATAATACAGCTTATTCAGCTTCTAAA
TTTGGAGGGGTCGGTCTCACGCAAAGCCTCGCGCTTGATCTTGCCGAACACAACATTCGGGTGAACAGCATTATGCCGGG
AAACTTGTTAAAATCGCCGATGTTCCAAAGCTTGATCCCGCAATACGCGAAAAAGCTCGGCATTCCAGAGAGCGAAGTAG
AGCGCGTGTACACCGAAAAAGTGCCTCTAGGACGGGGCTGTACGTATGATGACATCGCCAATGCCATCTTATTTTACGCC
TCTGACCAAGCATCTTATATGACGGGTCAATCGATCAATGTAACCGGGGGGCAGGTCATGCATTAA

Upstream 100 bases:

>100_bases
TGCCGGGAACACTGTACCTTGAACGAAAAGAACAACTGCCGGAGGTTTCAGCAGGAGACTGTATTCAAGTTAAAAGATTC
TCATAAGGAGCGGGTGCAAT

Downstream 100 bases:

>100_bases
AACAAGAGGGGGACGCGATGATGAACATGCTGATTGATTCAGCGCATATACCGGAGATTGAAAGATTGCTTGATTCATTT
CCCGCTGGCGGCGTCACGAC

Product: sorbitol-6-phosphate dehydrogenase

Products: NA

Alternate protein names: Glucitol-6-phosphate dehydrogenase; Ketosephosphate reductase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEMNKGKVALICGGGQSLGEALSYRMAEAGYDIAVADINGENAERTADHAAGQYGVKSLWIQADFTKEADVKKMIGRVTD
EFNKIDVMVYSAGIAKSNKITDFELEDWERTIEVNLTGYFLCARETSKVMIEQGSGSIIQINSKSGKVGSKHNTAYSASK
FGGVGLTQSLALDLAEHNIRVNSIMPGNLLKSPMFQSLIPQYAKKLGIPESEVERVYTEKVPLGRGCTYDDIANAILFYA
SDQASYMTGQSINVTGGQVMH

Sequences:

>Translated_261_residues
MEMNKGKVALICGGGQSLGEALSYRMAEAGYDIAVADINGENAERTADHAAGQYGVKSLWIQADFTKEADVKKMIGRVTD
EFNKIDVMVYSAGIAKSNKITDFELEDWERTIEVNLTGYFLCARETSKVMIEQGSGSIIQINSKSGKVGSKHNTAYSASK
FGGVGLTQSLALDLAEHNIRVNSIMPGNLLKSPMFQSLIPQYAKKLGIPESEVERVYTEKVPLGRGCTYDDIANAILFYA
SDQASYMTGQSINVTGGQVMH
>Mature_261_residues
MEMNKGKVALICGGGQSLGEALSYRMAEAGYDIAVADINGENAERTADHAAGQYGVKSLWIQADFTKEADVKKMIGRVTD
EFNKIDVMVYSAGIAKSNKITDFELEDWERTIEVNLTGYFLCARETSKVMIEQGSGSIIQINSKSGKVGSKHNTAYSASK
FGGVGLTQSLALDLAEHNIRVNSIMPGNLLKSPMFQSLIPQYAKKLGIPESEVERVYTEKVPLGRGCTYDDIANAILFYA
SDQASYMTGQSINVTGGQVMH

Specific function: Sorbitol metabolism. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=33.5849056603774, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=31.0756972111554, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI4758504, Length=273, Percent_Identity=32.2344322344322, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=27.6515151515151, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.8537549407115, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=26.984126984127, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=29.5774647887324, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI83715985, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=31.4432989690722, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI59889578, Length=201, Percent_Identity=27.8606965174129, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=23.828125, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7705925, Length=184, Percent_Identity=27.1739130434783, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40807363, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI142976729, Length=174, Percent_Identity=27.0114942528736, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI109715829, Length=258, Percent_Identity=24.8062015503876, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=30.6818181818182, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=25.6809338521401, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503817, Length=131, Percent_Identity=29.7709923664122, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=169, Percent_Identity=26.0355029585799, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI310128830, Length=217, Percent_Identity=24.4239631336406, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI310115468, Length=217, Percent_Identity=24.4239631336406, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=25.9459459459459, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=24.5810055865922, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=59.375, Blast_Score=302, Evalue=1e-83,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=33.587786259542, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=29.6875, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.046332046332, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=30.7086614173228, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=31.640625, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=28.125, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.9212598425197, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=23.6641221374046, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=207, Percent_Identity=23.1884057971014, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=236, Percent_Identity=24.1525423728814, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=24.7104247104247, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=32.8125, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=32.295719844358, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.5275590551181, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=28.957528957529, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17538182, Length=276, Percent_Identity=28.6231884057971, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=27.8810408921933, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.0442804428044, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=182, Percent_Identity=29.1208791208791, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=26.1029411764706, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=24.4274809160305, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=25.1908396946565, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=27.8810408921933, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.9245283018868, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=275, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.1954887218045, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=216, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=24.5353159851301, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=215, Percent_Identity=26.5116279069767, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=27.6497695852535, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=170, Percent_Identity=27.0588235294118, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=26.5384615384615, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=270, Percent_Identity=27.4074074074074, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=26.7924528301887, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=23.8341968911917, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=25.187969924812, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=25.2788104089219, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=24.901185770751, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=219, Percent_Identity=30.1369863013699, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=25.2830188679245, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=25.0996015936255, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=29.8039215686275, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=29.3893129770992, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=29.5275590551181, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=28.735632183908, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17737361, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=25.8823529411765, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI18859837, Length=208, Percent_Identity=28.3653846153846, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=25.4437869822485, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364892, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644337, Length=216, Percent_Identity=30.0925925925926, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=241, Percent_Identity=24.4813278008299, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221510726, Length=220, Percent_Identity=30, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358495, Length=185, Percent_Identity=25.9459459459459, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=25.0980392156863, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=27.9569892473118, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=28.494623655914, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=28.494623655914, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.140 [H]

Molecular weight: Translated: 28345; Mature: 28345

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMNKGKVALICGGGQSLGEALSYRMAEAGYDIAVADINGENAERTADHAAGQYGVKSLW
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEE
IQADFTKEADVKKMIGRVTDEFNKIDVMVYSAGIAKSNKITDFELEDWERTIEVNLTGYF
EEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEECCCCEEEEEEEEEEE
LCARETSKVMIEQGSGSIIQINSKSGKVGSKHNTAYSASKFGGVGLTQSLALDLAEHNIR
EEECCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEE
VNSIMPGNLLKSPMFQSLIPQYAKKLGIPESEVERVYTEKVPLGRGCTYDDIANAILFYA
EEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEE
SDQASYMTGQSINVTGGQVMH
CCCCCEECCCEEECCCCEECC
>Mature Secondary Structure
MEMNKGKVALICGGGQSLGEALSYRMAEAGYDIAVADINGENAERTADHAAGQYGVKSLW
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEE
IQADFTKEADVKKMIGRVTDEFNKIDVMVYSAGIAKSNKITDFELEDWERTIEVNLTGYF
EEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEECCCCEEEEEEEEEEE
LCARETSKVMIEQGSGSIIQINSKSGKVGSKHNTAYSASKFGGVGLTQSLALDLAEHNIR
EEECCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEE
VNSIMPGNLLKSPMFQSLIPQYAKKLGIPESEVERVYTEKVPLGRGCTYDDIANAILFYA
EEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEE
SDQASYMTGQSINVTGGQVMH
CCCCCEECCCEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3553176; 9205837; 9278503; 6384188 [H]