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The map label for this gene is glcR [H]

Identifier: 52787540

GI number: 52787540

Start: 3689231

End: 3690001

Strand: Reverse

Name: glcR [H]

Synonym: BLi03861

Alternate gene names: 52787540

Gene position: 3690001-3689231 (Counterclockwise)

Preceding gene: 52787541

Following gene: 52787539

Centisome position: 87.39

GC content: 48.25

Gene sequence:

>771_bases
GTGTACCAAGAGGAAAGGCTAATTTCCATCATCGACTATTTAAAAGAGCATAAACGGATTTCCGTTGAACAAATTTGTTC
TTTATTCGGAGTTTCAAGAGATACGGCAAGGCGGGATCTGGTTAAACTGCAAGAGCAAGGCGCCATTATCAGGACAAGGG
GCGGGGCGATTCTGCCCACCGTTCATGATGAGGTCAAAGACTATTCGGGCAGGCTGGGCATGGTTTCCGAAGAAAAAAGC
ATGATCGGAAAAGCAGCCGCTTCTTTAATCAGAGAAGGCGACCGCATTATTTTGGACGCTTCCACGACAGTCCAATCATG
CGCAGAGCATTTGCCGGATGTCAATTGCACGATCATCACCAATTCGATTAACCTTGCGGACGTTCTTTCCTCAAGAAAAG
GGGCTGACATCCGCCTGCTTGGAGGAAAGCTTCAAAAAGAGCACCGGTTTTTGTACGGCGCCTCTGTCATTGAAAAGCTG
TCATGCTATCATGTTGATAAAGCGCTGATCGGCGTGGTGGGGGTTTCTGAACATGGGCTTACAATCGCCCATGAGGAGGA
CGGAATGGTGAAGCGGAAAATGATTTCCCAAGCGAAGCAAGTCATAGCGCTTGCCGACCATTCGAAAATCGGGAGAACGG
ATTTTTACCGATACGCTGAACTCAGTGACATTGACCTTCTCATTACAGACCGGCTGCCGTCGAAACCGTTTCAGAAGCTG
CTTGATGAACACGATGTGGAGCTGCTTGTGGCTGAACATCACGATACTTAA

Upstream 100 bases:

>100_bases
TTTGCTTATCATTACTTATATACTCTTGATTTATTCGGCGTAATTGCTTATAATCACTTATAAATGATGAACTTTACTTG
CGCAAAGAAGGAATGATCCA

Downstream 100 bases:

>100_bases
GGGGGAATACAGCAGATGAAAATGATTGCGGTCGATTTAGACGGGACGCTGTTAAACAGTGAAAGCAAGATCTCAAAGAA
AAATATCGATGCGATTAAAA

Product: GlcR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MYQEERLISIIDYLKEHKRISVEQICSLFGVSRDTARRDLVKLQEQGAIIRTRGGAILPTVHDEVKDYSGRLGMVSEEKS
MIGKAAASLIREGDRIILDASTTVQSCAEHLPDVNCTIITNSINLADVLSSRKGADIRLLGGKLQKEHRFLYGASVIEKL
SCYHVDKALIGVVGVSEHGLTIAHEEDGMVKRKMISQAKQVIALADHSKIGRTDFYRYAELSDIDLLITDRLPSKPFQKL
LDEHDVELLVAEHHDT

Sequences:

>Translated_256_residues
MYQEERLISIIDYLKEHKRISVEQICSLFGVSRDTARRDLVKLQEQGAIIRTRGGAILPTVHDEVKDYSGRLGMVSEEKS
MIGKAAASLIREGDRIILDASTTVQSCAEHLPDVNCTIITNSINLADVLSSRKGADIRLLGGKLQKEHRFLYGASVIEKL
SCYHVDKALIGVVGVSEHGLTIAHEEDGMVKRKMISQAKQVIALADHSKIGRTDFYRYAELSDIDLLITDRLPSKPFQKL
LDEHDVELLVAEHHDT
>Mature_256_residues
MYQEERLISIIDYLKEHKRISVEQICSLFGVSRDTARRDLVKLQEQGAIIRTRGGAILPTVHDEVKDYSGRLGMVSEEKS
MIGKAAASLIREGDRIILDASTTVQSCAEHLPDVNCTIITNSINLADVLSSRKGADIRLLGGKLQKEHRFLYGASVIEKL
SCYHVDKALIGVVGVSEHGLTIAHEEDGMVKRKMISQAKQVIALADHSKIGRTDFYRYAELSDIDLLITDRLPSKPFQKL
LDEHDVELLVAEHHDT

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=244, Percent_Identity=30.327868852459, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=30, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=31.640625, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=30.4347826086957, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788069, Length=254, Percent_Identity=30.7086614173228, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=30, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=26.0162601626016, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790753, Length=242, Percent_Identity=28.5123966942149, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=24.609375, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=25.296442687747, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28571; Mature: 28571

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQEERLISIIDYLKEHKRISVEQICSLFGVSRDTARRDLVKLQEQGAIIRTRGGAILPT
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCEECCH
VHDEVKDYSGRLGMVSEEKSMIGKAAASLIREGDRIILDASTTVQSCAEHLPDVNCTIIT
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEEEE
NSINLADVLSSRKGADIRLLGGKLQKEHRFLYGASVIEKLSCYHVDKALIGVVGVSEHGL
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCE
TIAHEEDGMVKRKMISQAKQVIALADHSKIGRTDFYRYAELSDIDLLITDRLPSKPFQKL
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHH
LDEHDVELLVAEHHDT
HCCCCEEEEEECCCCC
>Mature Secondary Structure
MYQEERLISIIDYLKEHKRISVEQICSLFGVSRDTARRDLVKLQEQGAIIRTRGGAILPT
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCEECCH
VHDEVKDYSGRLGMVSEEKSMIGKAAASLIREGDRIILDASTTVQSCAEHLPDVNCTIIT
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEEEE
NSINLADVLSSRKGADIRLLGGKLQKEHRFLYGASVIEKLSCYHVDKALIGVVGVSEHGL
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCE
TIAHEEDGMVKRKMISQAKQVIALADHSKIGRTDFYRYAELSDIDLLITDRLPSKPFQKL
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHH
LDEHDVELLVAEHHDT
HCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]