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The map label for this gene is hprPe [H]

Identifier: 52787425

GI number: 52787425

Start: 3564892

End: 3565539

Strand: Reverse

Name: hprPe [H]

Synonym: BLi03743

Alternate gene names: 52787425

Gene position: 3565539-3564892 (Counterclockwise)

Preceding gene: 52787426

Following gene: 52787424

Centisome position: 84.44

GC content: 47.69

Gene sequence:

>648_bases
ATGAAAGTTAATACGGTTTTATTTGATTTGGATGGAACGCTCATCAATACAAATGAGCTGATTATCGCCTCATTTTTGCA
TACGCTCGATCATTATGCACCGGGACGCTATAAACGGGAGGATGTTCTTGCTTTCATCGGACCTTCCCTTTATGAAACGT
TCTCAAGCATTCAAAAGGATAAGGCTGAAGAAATGATCACCATGTACCGGACATTTAATCATCAGATGCATGATGAACTG
GTAACCGAGTATGAGACGGTTTACGAGACGCTTGAACGCCTTGCGGAAGAAGGCTATAAGCTCGGCATCGTCACGACAAA
GCTGCGGGACACCGTCATCATGGGGCTTAAACTGACTGGGCTTGATGCCTTTTTCGAGACGGTTGTGACGCTGGATGACG
TCGAGCGGCCGAAGCCTGACCCCGAGCCTGTTTTGCTCGCCCTTTCCAAGCTTGGCAGCCGTCCGGAAGAAGCCATTATG
ATCGGTGATAATTACCACGATATTTTAGCCGGGAAGAATGCTGGAACGAAAACAGCAGGCGTTGCATGGACGATTAAGGG
AGAAGAAAGCCTGGCCAAACACGAGCCTGATTTTATGCTTCAGCAAATGAGCGACCTCCTTCACATTCTTGGGGTGGAGA
AAGTTTGA

Upstream 100 bases:

>100_bases
CTTTTGTTGATCAGGCTTGCGACCGCGGTTCTGCTGACGATCGCGATTTCGCGCTTCTGGAGAAAGCCGGGTTATTCCGT
TCGCAGAAAGGAAGCTTTGT

Downstream 100 bases:

>100_bases
GAAAAACGAAGCGCTACCCGGTGTCCGGCGCCAATTCCTTATGGCACATCTATCAGACGGTTCCGTTTTTTAAAGTAGTC
AAAAACTTTATTGTCATTCA

Product: pyrophosphatase PpaX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVNTVLFDLDGTLINTNELIIASFLHTLDHYAPGRYKREDVLAFIGPSLYETFSSIQKDKAEEMITMYRTFNHQMHDEL
VTEYETVYETLERLAEEGYKLGIVTTKLRDTVIMGLKLTGLDAFFETVVTLDDVERPKPDPEPVLLALSKLGSRPEEAIM
IGDNYHDILAGKNAGTKTAGVAWTIKGEESLAKHEPDFMLQQMSDLLHILGVEKV

Sequences:

>Translated_215_residues
MKVNTVLFDLDGTLINTNELIIASFLHTLDHYAPGRYKREDVLAFIGPSLYETFSSIQKDKAEEMITMYRTFNHQMHDEL
VTEYETVYETLERLAEEGYKLGIVTTKLRDTVIMGLKLTGLDAFFETVVTLDDVERPKPDPEPVLLALSKLGSRPEEAIM
IGDNYHDILAGKNAGTKTAGVAWTIKGEESLAKHEPDFMLQQMSDLLHILGVEKV
>Mature_215_residues
MKVNTVLFDLDGTLINTNELIIASFLHTLDHYAPGRYKREDVLAFIGPSLYETFSSIQKDKAEEMITMYRTFNHQMHDEL
VTEYETVYETLERLAEEGYKLGIVTTKLRDTVIMGLKLTGLDAFFETVVTLDDVERPKPDPEPVLLALSKLGSRPEEAIM
IGDNYHDILAGKNAGTKTAGVAWTIKGEESLAKHEPDFMLQQMSDLLHILGVEKV

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=238, Percent_Identity=27.3109243697479, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24251; Mature: 24251

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNTVLFDLDGTLINTNELIIASFLHTLDHYAPGRYKREDVLAFIGPSLYETFSSIQKD
CCCEEEEEECCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHH
KAEEMITMYRTFNHQMHDELVTEYETVYETLERLAEEGYKLGIVTTKLRDTVIMGLKLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHEEEEEECH
LDAFFETVVTLDDVERPKPDPEPVLLALSKLGSRPEEAIMIGDNYHDILAGKNAGTKTAG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCCCCCCCC
VAWTIKGEESLAKHEPDFMLQQMSDLLHILGVEKV
EEEEEECCHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVNTVLFDLDGTLINTNELIIASFLHTLDHYAPGRYKREDVLAFIGPSLYETFSSIQKD
CCCEEEEEECCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHH
KAEEMITMYRTFNHQMHDELVTEYETVYETLERLAEEGYKLGIVTTKLRDTVIMGLKLTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHEEEEEECH
LDAFFETVVTLDDVERPKPDPEPVLLALSKLGSRPEEAIMIGDNYHDILAGKNAGTKTAG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCCCCCCCC
VAWTIKGEESLAKHEPDFMLQQMSDLLHILGVEKV
EEEEEECCHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9465101; 12359880 [H]