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The map label for this gene is cynR [H]

Identifier: 52787201

GI number: 52787201

Start: 3349089

End: 3349997

Strand: Direct

Name: cynR [H]

Synonym: BLi03510

Alternate gene names: 52787201

Gene position: 3349089-3349997 (Clockwise)

Preceding gene: 52787199

Following gene: 52787214

Centisome position: 79.31

GC content: 50.28

Gene sequence:

>909_bases
TTGGAGCTAAAGCAATTGGAATACTTTATGGCATTGTGCCGGGAGCTTCATTTTACCCGCGCCGCCGAAAAACTGAATAT
CGCTCAGCCCTCGCTGAGCCAGCAAATCCGTTTGCTTGAACACGAAATCGGAATGCCTTTGTTTAACCGTTCAGGCAAAC
GCACCGTGATGACGGAAGCGGGAAATATTCTGCTCCAGCACTGTTACAATATCTTTCATGAACTGTCACAGGCGCGAGAC
GCGATCAGCGAGCTTCAAGGTTTAAAACGGGGAACGCTTAAAATCGGGGCGCTTTTGACCGTGGTTAATTATTTGCTTCC
CCGGACCGTGGTCGAATTTCACCGCAGCTACCCCAATATTGAATTGTCTGTTTTAGGGCTGAGAACCGGGGATATTTACG
ACCGGCTGCTGCAAAATGAGCTCGACTTGGGCATTGTAGCCCAGCGGGTGGAACATCGTGACTTAGAAGCCGTCCCATTC
CTTACCCAGCATCTCGCCCTCGCGGCGCCTGTTGACAATCCGGTTGCAAAGCGGCAGTTTGTCACGCTTGACGTGTTAAG
GGAGATTCCATCCATTTTGCTGCCTGAGACGTATTTTTTGCGGCAGCTGATCAACGAAAAGTGCCGCACGCTTGGATTCG
AGCCCCGGCCGGTCATGGAAATGACAACGATGGAATCGATCATGAACATGGTCGGTAAAGGCATCGGCGCCACCATTTTG
CCGAAAGGCTATCTTAATGCTATTGGAAATAAATCCATTCAGACGATTCCGATACAAAAGCCGGATTTGACGACGGAGAT
CAGCATCGTTTACCGTAAAAACAAGCATATGTGCGCTGCAAGCCGGGTGTTTATGAAACTGCTGATTTCCTCGGTCAAAA
GCGAAACCGCTGATGCGCCGCCGCGTTAA

Upstream 100 bases:

>100_bases
ACCTCTTACCATAAAACTATTCAATCGTTATTATAAAAACAATAGGTTAAACCTATCATTGGAATTCGGCTGTTTTTCAG
ATGGAGAGGAGGAAAGAGCA

Downstream 100 bases:

>100_bases
AAGAAAAATCCTCTGCATGTCTGCAGAGGATTTATGTTTAGGCTTTGTGTGAGTCATAGCGTTTTCCGTTAATATACAGA
TTCGAAAAAACGGGGTCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MELKQLEYFMALCRELHFTRAAEKLNIAQPSLSQQIRLLEHEIGMPLFNRSGKRTVMTEAGNILLQHCYNIFHELSQARD
AISELQGLKRGTLKIGALLTVVNYLLPRTVVEFHRSYPNIELSVLGLRTGDIYDRLLQNELDLGIVAQRVEHRDLEAVPF
LTQHLALAAPVDNPVAKRQFVTLDVLREIPSILLPETYFLRQLINEKCRTLGFEPRPVMEMTTMESIMNMVGKGIGATIL
PKGYLNAIGNKSIQTIPIQKPDLTTEISIVYRKNKHMCAASRVFMKLLISSVKSETADAPPR

Sequences:

>Translated_302_residues
MELKQLEYFMALCRELHFTRAAEKLNIAQPSLSQQIRLLEHEIGMPLFNRSGKRTVMTEAGNILLQHCYNIFHELSQARD
AISELQGLKRGTLKIGALLTVVNYLLPRTVVEFHRSYPNIELSVLGLRTGDIYDRLLQNELDLGIVAQRVEHRDLEAVPF
LTQHLALAAPVDNPVAKRQFVTLDVLREIPSILLPETYFLRQLINEKCRTLGFEPRPVMEMTTMESIMNMVGKGIGATIL
PKGYLNAIGNKSIQTIPIQKPDLTTEISIVYRKNKHMCAASRVFMKLLISSVKSETADAPPR
>Mature_302_residues
MELKQLEYFMALCRELHFTRAAEKLNIAQPSLSQQIRLLEHEIGMPLFNRSGKRTVMTEAGNILLQHCYNIFHELSQARD
AISELQGLKRGTLKIGALLTVVNYLLPRTVVEFHRSYPNIELSVLGLRTGDIYDRLLQNELDLGIVAQRVEHRDLEAVPF
LTQHLALAAPVDNPVAKRQFVTLDVLREIPSILLPETYFLRQLINEKCRTLGFEPRPVMEMTTMESIMNMVGKGIGATIL
PKGYLNAIGNKSIQTIPIQKPDLTTEISIVYRKNKHMCAASRVFMKLLISSVKSETADAPPR

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=32.0422535211268, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=30.03663003663, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=26.9896193771626, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788887, Length=299, Percent_Identity=29.0969899665552, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=28.5234899328859, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=27.9352226720648, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787530, Length=266, Percent_Identity=25.5639097744361, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788748, Length=287, Percent_Identity=26.4808362369338, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787806, Length=278, Percent_Identity=24.8201438848921, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=26.8292682926829, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788296, Length=239, Percent_Identity=28.0334728033473, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082132, Length=247, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=29.6551724137931, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=23.921568627451, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786401, Length=169, Percent_Identity=27.2189349112426, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081904, Length=207, Percent_Identity=28.5024154589372, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787589, Length=157, Percent_Identity=31.2101910828025, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787128, Length=158, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=240, Percent_Identity=24.1666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=148, Percent_Identity=30.4054054054054, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789639, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790262, Length=317, Percent_Identity=23.0283911671924, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34202; Mature: 34202

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKQLEYFMALCRELHFTRAAEKLNIAQPSLSQQIRLLEHEIGMPLFNRSGKRTVMTEA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCCCCEEEHHHH
GNILLQHCYNIFHELSQARDAISELQGLKRGTLKIGALLTVVNYLLPRTVVEFHRSYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELSVLGLRTGDIYDRLLQNELDLGIVAQRVEHRDLEAVPFLTQHLALAAPVDNPVAKRQF
EEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
VTLDVLREIPSILLPETYFLRQLINEKCRTLGFEPRPVMEMTTMESIMNMVGKGIGATIL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
PKGYLNAIGNKSIQTIPIQKPDLTTEISIVYRKNKHMCAASRVFMKLLISSVKSETADAP
CHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PR
CC
>Mature Secondary Structure
MELKQLEYFMALCRELHFTRAAEKLNIAQPSLSQQIRLLEHEIGMPLFNRSGKRTVMTEA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCCCCEEEHHHH
GNILLQHCYNIFHELSQARDAISELQGLKRGTLKIGALLTVVNYLLPRTVVEFHRSYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELSVLGLRTGDIYDRLLQNELDLGIVAQRVEHRDLEAVPFLTQHLALAAPVDNPVAKRQF
EEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
VTLDVLREIPSILLPETYFLRQLINEKCRTLGFEPRPVMEMTTMESIMNMVGKGIGATIL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
PKGYLNAIGNKSIQTIPIQKPDLTTEISIVYRKNKHMCAASRVFMKLLISSVKSETADAP
CHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]