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The map label for this gene is cssR [H]

Identifier: 52787173

GI number: 52787173

Start: 3323484

End: 3324158

Strand: Direct

Name: cssR [H]

Synonym: BLi03482

Alternate gene names: 52787173

Gene position: 3323484-3324158 (Clockwise)

Preceding gene: 52787171

Following gene: 52787174

Centisome position: 78.71

GC content: 44.44

Gene sequence:

>675_bases
TTGTCATACTCCATTTATCTAGTTGAAGATGAAGAGAATTTAAATGAATTGCTGACAAAATACTTAGAGAGTGAAGGCTG
GCACGTCACTTCTTTTCTAAACGGTGAAAGCGCCAGGCAAAAAATAGGCCAGTCACCTCATTTATGGATTCTCGATATCA
TGTTACCAGATATCGACGGGTATACGCTAATAAAAGAAATAAAAAATCAAGATCCGGAAGTCCCCGTCATTTTTATTTCT
GCGCGCGATGCCGACATTGACAGAGTGCTGGGGCTTGAACTGGGCAGCAGCGACTATATATCTAAGCCGTTTCTCCCCAG
GGAGCTGATCATCCGCGTGCAAAAGCTGCTCAAGCTGATTTATAAAGAAGAACCGCCTGAGAAGAAAAAAGGAACGCCGG
TTTCCTGCTATGAAGTCTATGAAGACTTGAGAGAAGTCTATGAAAATGGCAGCATGATCAATTTGACGTCAAAGGAATTT
GATCTTCTGCTTCTATTTATAAACAACCAGGGCCGCGCCTTTTCAAGGGAGGATATTCTCACCAGCGTCTGGGGAGTCGA
TTACTTCGGAACCGACCGCGTCGTCGACGATCTTGTCAGAAGGCTGCGCAAGAAAATGCCCGAACTGAAAGTGGAAACCA
TCTACGGGTTTGGCTACAGGATGTTGAAATCATGA

Upstream 100 bases:

>100_bases
ACATTGTGGGATAAAAATGAAAAGAATATGTGAAATTATGAAAATTGACCAGACTTATGTTAAAACTAGTATAATGACGT
AGAAAGGATGTGAACCGCCC

Downstream 100 bases:

>100_bases
AGAACAGGTCGCTCGCCTTTCAAATTTGGAGTGTCATTTGCGGCATCCTGTTAACGGTCTCGATTTTGCTGACGTTTCTA
TTCTCGACGACACTGCAGAA

Product: CssR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSYSIYLVEDEENLNELLTKYLESEGWHVTSFLNGESARQKIGQSPHLWILDIMLPDIDGYTLIKEIKNQDPEVPVIFIS
ARDADIDRVLGLELGSSDYISKPFLPRELIIRVQKLLKLIYKEEPPEKKKGTPVSCYEVYEDLREVYENGSMINLTSKEF
DLLLLFINNQGRAFSREDILTSVWGVDYFGTDRVVDDLVRRLRKKMPELKVETIYGFGYRMLKS

Sequences:

>Translated_224_residues
MSYSIYLVEDEENLNELLTKYLESEGWHVTSFLNGESARQKIGQSPHLWILDIMLPDIDGYTLIKEIKNQDPEVPVIFIS
ARDADIDRVLGLELGSSDYISKPFLPRELIIRVQKLLKLIYKEEPPEKKKGTPVSCYEVYEDLREVYENGSMINLTSKEF
DLLLLFINNQGRAFSREDILTSVWGVDYFGTDRVVDDLVRRLRKKMPELKVETIYGFGYRMLKS
>Mature_223_residues
SYSIYLVEDEENLNELLTKYLESEGWHVTSFLNGESARQKIGQSPHLWILDIMLPDIDGYTLIKEIKNQDPEVPVIFISA
RDADIDRVLGLELGSSDYISKPFLPRELIIRVQKLLKLIYKEEPPEKKKGTPVSCYEVYEDLREVYENGSMINLTSKEFD
LLLLFINNQGRAFSREDILTSVWGVDYFGTDRVVDDLVRRLRKKMPELKVETIYGFGYRMLKS

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=35.2173913043478, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=31.7180616740088, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=35.1351351351351, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=33.1914893617021, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=34.9344978165939, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=33.4821428571429, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=34.6320346320346, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.7719298245614, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.2727272727273, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=30.2752293577982, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=28.3783783783784, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=31.1688311688312, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=26.8181818181818, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26067; Mature: 25936

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSIYLVEDEENLNELLTKYLESEGWHVTSFLNGESARQKIGQSPHLWILDIMLPDIDG
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCC
YTLIKEIKNQDPEVPVIFISARDADIDRVLGLELGSSDYISKPFLPRELIIRVQKLLKLI
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YKEEPPEKKKGTPVSCYEVYEDLREVYENGSMINLTSKEFDLLLLFINNQGRAFSREDIL
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCCCCHHHHH
TSVWGVDYFGTDRVVDDLVRRLRKKMPELKVETIYGFGYRMLKS
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure 
SYSIYLVEDEENLNELLTKYLESEGWHVTSFLNGESARQKIGQSPHLWILDIMLPDIDG
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCC
YTLIKEIKNQDPEVPVIFISARDADIDRVLGLELGSSDYISKPFLPRELIIRVQKLLKLI
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YKEEPPEKKKGTPVSCYEVYEDLREVYENGSMINLTSKEFDLLLLFINNQGRAFSREDIL
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCCCCHHHHH
TSVWGVDYFGTDRVVDDLVRRLRKKMPELKVETIYGFGYRMLKS
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]