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The map label for this gene is phoR [H]

Identifier: 52786787

GI number: 52786787

Start: 2943216

End: 2944961

Strand: Reverse

Name: phoR [H]

Synonym: BLi03058

Alternate gene names: 52786787

Gene position: 2944961-2943216 (Counterclockwise)

Preceding gene: 52786788

Following gene: 52786786

Centisome position: 69.74

GC content: 46.91

Gene sequence:

>1746_bases
ATGATTAAATTCCGGACCCGGCTTTTAGCTGCCCTGCTGACGCTTTTGATTCTCGTATTTGCTTCACTCGGTTTTCTGCT
CGTTCACTTGTTTCACTCCTCTTACGATGCCAAACTGAGCAGCCATATTGAAAAAGAGGCCGCTTTGGTCGCTTCATTGG
CAAATGGTGAAAACATGAAGTCTTCGGAGCAAGGAGCTATTTTAGAGAAGGCAAGCCGTGAACTGGACAGTCGTGTATCG
CTTATTGATACAAAAGGTCAGGTTCTTTTTCATTTTGGGGGCCGCGCCGAAGAGCAATCCGTTATCAAGGAAGCGCTTGA
GTCGGATTTAAACGGTGAAGGAGGAGGCTTCAGGATCAACCCTGATGACGAGTCCGTTTACCGTTACGTGCAGCCGCTCA
AAGATGACGGGAATGTGAATGGATATATTCTGATCAGCACTCCTGTCGATTCATTGCAAGACATCAATCAAAAGATCTGG
ATTCTCCTCGGCGTGAGCCTTGGAACGGCCTTTTTAATCATCGCCGGGCTTGGGGCGAGAATAACCTCTCAATATACGAA
TCCGATTGAGTCTGCGACACAAGTGGCGATTGAGCTTGCCAAAGGAAACTATAAAGCAAGAACATTCAACGAAGATGAAA
CGATGCTGAGCCAGTCCATCAATATGCTGGCGCAGAACCTGCAGGACATGACAAGAGCCCAGGAAATGCAGCGCGACCGT
CTGCAAACCGTCATCGAAAATATCGATTCCGGTCTGATCTTAATCGACGGAAAGGGTTATATTCACCTTGTGAACCGCGC
TTATCAAAAGCAATTTCACGTAGAAGCCGATCAGCTTCTTTACCATTTCTATCACGAAGTGCTCGAACACGAAGAGATCA
TTAATCTCATTGAAGAAATTTTTATGACGGAAGCAAAGGTCCGCAAAATGTTTAAACTGCCGATCAAAATTGAAAGAAGG
TATTTTGAAGTCGACGGGGTTCCGATTATCGGCATCAATGATGAGTGGAAAGGCATCGTTCTCGTTTTCCATGACATGAC
GGAAAGAAAGCAGCTTGAAGAAATGAGGAAGGACTTTGTCGCCAATGTCTCCCATGAGCTGAAAACGCCGATTACATCAA
TCAAAGGGTTCACCGAAACGCTTCTGGACGGAGCGATGAACGAACGGGAGACGCTGTTGCAGTTTCTATCGATCATCTTA
AAAGAGAGCAGCCGTCTGCAAACCTTGATCCAGGACCTGTTGGATCTGTCGAAAATCGAACAGCAAAACTTCACCCTGAA
TATTCAAAATTGCAATATCGGTGAAATCCTCGCCGAAATTGAGATGCTTTTGAAGAATAAAGCGGAGGAAAAAGGAATCA
CCTTGACACTGGAAAAGCCGGATAAGCCGGCCGTTGCTTCCGGAGACCCGCACAGACTAAAGCAGATCTTTTTGAATTTG
GTGAACAATGCGCTCACATATACGCCTGAAGATGGAAGCGTGACGATTTCGGCTGATGTTCTGGAAGATGCAGTGCAAGT
CAAAGTGAGGGATACGGGCATCGGGATCAAGCAGTCCGAAATCCCGAGGATATTTGAACGGTTCTACAGGATCGATAAAG
ACAGGAGCAGAAATTCAGGAGGAACCGGTCTCGGTCTTGCGATCGTCAAGCATTTAGTCGAAGCCCACCAAGGCGAAATC
GACGTCGAAAGCGAGCGGGGAAAAGGCACCGAATTCACGGTCCGCTTAAAACGCGCATCCGAGTAG

Upstream 100 bases:

>100_bases
ATCAGCCACCTTCGCGATAAGATCGAAAAAAATACAAAAAAACCGGAATACATTAAAACAATCAGAGGTCTTGGCTACAA
AATGGAGGAGCCGAAACTGA

Downstream 100 bases:

>100_bases
CTTCATTTAGCAAACTTTACAAAGGCTTAACAACTTTTATATATATGGTTAAAACTTGGCTGATAGGATCATTAGTGAAC
CCCTTCATCCAAGGAGCCAT

Product: PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MIKFRTRLLAALLTLLILVFASLGFLLVHLFHSSYDAKLSSHIEKEAALVASLANGENMKSSEQGAILEKASRELDSRVS
LIDTKGQVLFHFGGRAEEQSVIKEALESDLNGEGGGFRINPDDESVYRYVQPLKDDGNVNGYILISTPVDSLQDINQKIW
ILLGVSLGTAFLIIAGLGARITSQYTNPIESATQVAIELAKGNYKARTFNEDETMLSQSINMLAQNLQDMTRAQEMQRDR
LQTVIENIDSGLILIDGKGYIHLVNRAYQKQFHVEADQLLYHFYHEVLEHEEIINLIEEIFMTEAKVRKMFKLPIKIERR
YFEVDGVPIIGINDEWKGIVLVFHDMTERKQLEEMRKDFVANVSHELKTPITSIKGFTETLLDGAMNERETLLQFLSIIL
KESSRLQTLIQDLLDLSKIEQQNFTLNIQNCNIGEILAEIEMLLKNKAEEKGITLTLEKPDKPAVASGDPHRLKQIFLNL
VNNALTYTPEDGSVTISADVLEDAVQVKVRDTGIGIKQSEIPRIFERFYRIDKDRSRNSGGTGLGLAIVKHLVEAHQGEI
DVESERGKGTEFTVRLKRASE

Sequences:

>Translated_581_residues
MIKFRTRLLAALLTLLILVFASLGFLLVHLFHSSYDAKLSSHIEKEAALVASLANGENMKSSEQGAILEKASRELDSRVS
LIDTKGQVLFHFGGRAEEQSVIKEALESDLNGEGGGFRINPDDESVYRYVQPLKDDGNVNGYILISTPVDSLQDINQKIW
ILLGVSLGTAFLIIAGLGARITSQYTNPIESATQVAIELAKGNYKARTFNEDETMLSQSINMLAQNLQDMTRAQEMQRDR
LQTVIENIDSGLILIDGKGYIHLVNRAYQKQFHVEADQLLYHFYHEVLEHEEIINLIEEIFMTEAKVRKMFKLPIKIERR
YFEVDGVPIIGINDEWKGIVLVFHDMTERKQLEEMRKDFVANVSHELKTPITSIKGFTETLLDGAMNERETLLQFLSIIL
KESSRLQTLIQDLLDLSKIEQQNFTLNIQNCNIGEILAEIEMLLKNKAEEKGITLTLEKPDKPAVASGDPHRLKQIFLNL
VNNALTYTPEDGSVTISADVLEDAVQVKVRDTGIGIKQSEIPRIFERFYRIDKDRSRNSGGTGLGLAIVKHLVEAHQGEI
DVESERGKGTEFTVRLKRASE
>Mature_581_residues
MIKFRTRLLAALLTLLILVFASLGFLLVHLFHSSYDAKLSSHIEKEAALVASLANGENMKSSEQGAILEKASRELDSRVS
LIDTKGQVLFHFGGRAEEQSVIKEALESDLNGEGGGFRINPDDESVYRYVQPLKDDGNVNGYILISTPVDSLQDINQKIW
ILLGVSLGTAFLIIAGLGARITSQYTNPIESATQVAIELAKGNYKARTFNEDETMLSQSINMLAQNLQDMTRAQEMQRDR
LQTVIENIDSGLILIDGKGYIHLVNRAYQKQFHVEADQLLYHFYHEVLEHEEIINLIEEIFMTEAKVRKMFKLPIKIERR
YFEVDGVPIIGINDEWKGIVLVFHDMTERKQLEEMRKDFVANVSHELKTPITSIKGFTETLLDGAMNERETLLQFLSIIL
KESSRLQTLIQDLLDLSKIEQQNFTLNIQNCNIGEILAEIEMLLKNKAEEKGITLTLEKPDKPAVASGDPHRLKQIFLNL
VNNALTYTPEDGSVTISADVLEDAVQVKVRDTGIGIKQSEIPRIFERFYRIDKDRSRNSGGTGLGLAIVKHLVEAHQGEI
DVESERGKGTEFTVRLKRASE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=290, Percent_Identity=35.1724137931034, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786783, Length=252, Percent_Identity=33.7301587301587, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=33.0855018587361, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=36.4406779661017, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=33.7719298245614, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=33.9285714285714, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=31.9327731092437, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=24.9329758713137, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=32.5688073394495, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=30.2127659574468, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=30.3418803418803, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=28.936170212766, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=27.1929824561404, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790300, Length=244, Percent_Identity=28.6885245901639, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=26.1261261261261, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789808, Length=223, Percent_Identity=29.1479820627803, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=26.551724137931, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789403, Length=248, Percent_Identity=27.8225806451613, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790567, Length=357, Percent_Identity=26.6106442577031, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65468; Mature: 65468

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKFRTRLLAALLTLLILVFASLGFLLVHLFHSSYDAKLSSHIEKEAALVASLANGENMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SSEQGAILEKASRELDSRVSLIDTKGQVLFHFGGRAEEQSVIKEALESDLNGEGGGFRIN
CCCCCHHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEC
PDDESVYRYVQPLKDDGNVNGYILISTPVDSLQDINQKIWILLGVSLGTAFLIIAGLGAR
CCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCHH
ITSQYTNPIESATQVAIELAKGNYKARTFNEDETMLSQSINMLAQNLQDMTRAQEMQRDR
HHHHHCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVIENIDSGLILIDGKGYIHLVNRAYQKQFHVEADQLLYHFYHEVLEHEEIINLIEEI
HHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMTEAKVRKMFKLPIKIERRYFEVDGVPIIGINDEWKGIVLVFHDMTERKQLEEMRKDFV
HHHHHHHHHHHHCCCEEECEEEEECCEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHH
ANVSHELKTPITSIKGFTETLLDGAMNERETLLQFLSIILKESSRLQTLIQDLLDLSKIE
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
QQNFTLNIQNCNIGEILAEIEMLLKNKAEEKGITLTLEKPDKPAVASGDPHRLKQIFLNL
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
VNNALTYTPEDGSVTISADVLEDAVQVKVRDTGIGIKQSEIPRIFERFYRIDKDRSRNSG
HHCCEEECCCCCCEEEEHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAIVKHLVEAHQGEIDVESERGKGTEFTVRLKRASE
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MIKFRTRLLAALLTLLILVFASLGFLLVHLFHSSYDAKLSSHIEKEAALVASLANGENMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SSEQGAILEKASRELDSRVSLIDTKGQVLFHFGGRAEEQSVIKEALESDLNGEGGGFRIN
CCCCCHHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEC
PDDESVYRYVQPLKDDGNVNGYILISTPVDSLQDINQKIWILLGVSLGTAFLIIAGLGAR
CCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCHH
ITSQYTNPIESATQVAIELAKGNYKARTFNEDETMLSQSINMLAQNLQDMTRAQEMQRDR
HHHHHCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVIENIDSGLILIDGKGYIHLVNRAYQKQFHVEADQLLYHFYHEVLEHEEIINLIEEI
HHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMTEAKVRKMFKLPIKIERRYFEVDGVPIIGINDEWKGIVLVFHDMTERKQLEEMRKDFV
HHHHHHHHHHHHCCCEEECEEEEECCEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHH
ANVSHELKTPITSIKGFTETLLDGAMNERETLLQFLSIILKESSRLQTLIQDLLDLSKIE
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
QQNFTLNIQNCNIGEILAEIEMLLKNKAEEKGITLTLEKPDKPAVASGDPHRLKQIFLNL
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
VNNALTYTPEDGSVTISADVLEDAVQVKVRDTGIGIKQSEIPRIFERFYRIDKDRSRNSG
HHCCEEECCCCCCEEEEHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAIVKHLVEAHQGEIDVESERGKGTEFTVRLKRASE
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]