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The map label for this gene is ysnA [C]

Identifier: 52786715

GI number: 52786715

Start: 2866895

End: 2867485

Strand: Reverse

Name: ysnA [C]

Synonym: BLi02984

Alternate gene names: 52786715

Gene position: 2867485-2866895 (Counterclockwise)

Preceding gene: 52786716

Following gene: 52786714

Centisome position: 67.91

GC content: 50.25

Gene sequence:

>591_bases
ATGAAGGAAGTCATCATTGCCACGAAAAACGAAGGGAAAGTCAGGGAATTCAAAGCGATGCTTGAACCGAGGGGCTACGA
TGTCAAATCTTTACTGGACATCGGCTATACACCCGAAATCGAAGAAACCGGGCAGACTTTTGAAGAAAACGCTGTGATTA
AAGCGGAAACAATTTCGAAAGAAACCGGAAAAATCGTGATTGCCGACGACTCCGGCCTGTCTGTCGACTATCTCGGCGGC
AGCCCCGGCGTATACTCGGCCCGCTATGCAGGAGAAGAGAAAAACGATCTCGCCAATCTGAAAAAGCTATTGAAAGAGCT
CGAAGGGGTGGAAAAAGAAGACCGTTCCGCGAGGTTCAGATGCGCGCTCGCAATATGCATTCCCGGACAGGAAACGAAAA
CGGTCGAAGGTTCTGTGGAAGGGTACATTACCGAAGAGCCGCGCGGCACAAACGGCTTCGGCTACGACCCGGTTTTTCTC
GTCAAAGACAAAGATCAAACGATGGCCGAGCTCTCAAGCGGCGAAAAGAACAAAATCAGCCACAGAGCGGAAGCGCTGAA
AAAGCTGTCCGCTTTATTGGATCAAGCGTAA

Upstream 100 bases:

>100_bases
GGCTGAAAAAGGGATCGCCGAACTCCTCGAAAAGCAGAAAGAAGTGCTCGGCGACGTTGCATTATCTATTCAACAATAAC
ATGAGAAAGGCTGATACACG

Downstream 100 bases:

>100_bases
AGGAGGAGGGCCGATCATGAAGGTTCTGATTGTCAGCGACAGCCACGGCCTTGAAGACGAACTGGAAATGATCGCTGAGC
GGCACGGGAAGGAAACAGAT

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISKETGKIVIADDSGLSVDYLGG
SPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFRCALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFL
VKDKDQTMAELSSGEKNKISHRAEALKKLSALLDQA

Sequences:

>Translated_196_residues
MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISKETGKIVIADDSGLSVDYLGG
SPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFRCALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFL
VKDKDQTMAELSSGEKNKISHRAEALKKLSALLDQA
>Mature_196_residues
MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISKETGKIVIADDSGLSVDYLGG
SPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFRCALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFL
VKDKDQTMAELSSGEKNKISHRAEALKKLSALLDQA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI31657144, Length=144, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI15626999, Length=144, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=48.6910994764398, Blast_Score=178, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19920712, Length=197, Percent_Identity=33.502538071066, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_BACLD (Q65GG3)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080128.1
- RefSeq:   YP_092544.1
- ProteinModelPortal:   Q65GG3
- SMR:   Q65GG3
- STRING:   Q65GG3
- EnsemblBacteria:   EBBACT00000054521
- EnsemblBacteria:   EBBACT00000058865
- GeneID:   3028174
- GeneID:   3098491
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02984
- KEGG:   bli:BL00311
- NMPDR:   fig|279010.5.peg.3333
- eggNOG:   COG0127
- GeneTree:   EBGT00050000001334
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- ProtClustDB:   PRK14822
- BioCyc:   BLIC279010-1:BLI02984-MONOMER
- BioCyc:   BLIC279010:BL00311-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21513; Mature: 21513

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISK
CCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHCCCHHHCCEEEEECCCC
ETGKIVIADDSGLSVDYLGGSPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFR
CCCEEEEECCCCCEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
CALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFLVKDKDQTMAELSSGEKNKIS
EEEEEEECCCCCCEECCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHCCCHHHHH
HRAEALKKLSALLDQA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVIIATKNEGKVREFKAMLEPRGYDVKSLLDIGYTPEIEETGQTFEENAVIKAETISK
CCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHCCCHHHCCEEEEECCCC
ETGKIVIADDSGLSVDYLGGSPGVYSARYAGEEKNDLANLKKLLKELEGVEKEDRSARFR
CCCEEEEECCCCCEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
CALAICIPGQETKTVEGSVEGYITEEPRGTNGFGYDPVFLVKDKDQTMAELSSGEKNKIS
EEEEEEECCCCCCEECCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHCCCHHHHH
HRAEALKKLSALLDQA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA