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The map label for this gene is obgE [H]

Identifier: 52786651

GI number: 52786651

Start: 2805864

End: 2807150

Strand: Reverse

Name: obgE [H]

Synonym: BLi02919

Alternate gene names: 52786651

Gene position: 2807150-2805864 (Counterclockwise)

Preceding gene: 52786652

Following gene: 52786650

Centisome position: 66.48

GC content: 51.13

Gene sequence:

>1287_bases
ATGTTTGTTGATCAGGTGAAAATATACGTAAAAGGCGGAGACGGAGGCAACGGTATGGTTGCTTTCCGCCGCGAAAAATA
TGTGCCAAAAGGAGGCCCTGCCGGAGGTGACGGCGGAAAAGGCGGAGACGTCGTTTTCAAAGTTGACGAAGGTCTCAGCA
CGCTGATGGATTTTAGATATCAAAGACATTTTAAGGCAGCGCGCGGAGAACACGGCATGTCTAAAAACCAGCACGGCCGA
AATGCCGAAGACATGGTTGTGAAAGTCCCGCCCGGCACGGTTGTCATTGACGATGATACAAAACAGGTCATCGCTGATTT
AACGGAGCACGGACAGGAAGCCGTCATCGCAAAAGGGGGACGCGGCGGACGGGGCAATACACGTTTTGCGACGCCTGCCA
ACCCGGCGCCGCAGCTTTCTGAAAACGGCGAACCCGGCAAGGAGCGCTATATTGTTCTCGAGCTGAAAGTTTTGGCAGAT
GTCGGTCTTGTCGGCTTCCCAAGCGTCGGAAAATCAACGCTCCTGTCTGTCGTGTCTTCGGCCAAGCCGAAAATTGCCGA
TTACCACTTTACAACGCTGAACCCGAATCTCGGAATGGTCGAAACGGAAGACGGCCGCAGCTTTGTAATGGCGGATCTTC
CGGGACTGATTGAGGGGGCGCACGAAGGAGTTGGCCTCGGACACCAATTCCTCAGGCATATCGAAAGAACGCGCGTCATC
GTGCACGTTATTGACATGTCGGGTCTTGAAGGGCGCGACCCGTATGAAGATTATGTGACCATTAATAAAGAGCTTGAACA
GTATAATCTCAGGCTGACAGAACGTCCTCAAATTATTGTCGCCAATAAAATGGATATGCCGGATGCGGAAGAAAATCTGA
AGGCTTTCAAAGAAAAGCTCACAGATGATTATCCTGTTTTTCCAATCAGCGCGGTGACCAGACAAGGCTTGAGGGATCTG
CTGTTTGAAATTGCCGACCGTTTGGAAACGACGCCGGAATTCCCGCTCTACGACGAAGAAGACATGGCTGAAAACAGAGT
CATGTATAAGCTTGAGGATGAGGAAGCGCCGTTTGAGATCAGCCGTGATCCTGACGGCACCTTCGTGCTCAGCGGAGCCA
AGCTTGAACGCTTATTTAAAATGACGGACTTTTCAAGAGATGAGTCTGTTAAGCGTTTTGCCAGACAGCTTCGCGGAATG
GGCGTCGATGATGCGCTTCGGGCCCGCGGTGCAAAAGACGGGGATACGATCCGTCTTCTCGAATTTGAATTTGAATTTAT
CGACTGA

Upstream 100 bases:

>100_bases
ACTTTTATGAAATCAAGCGGTTTGATGTAACAGACCGTGAGTGCATCGCCGAAATTCATATCAAGTAAAGCGGTTTTTTA
GGAATAGAACGGAGGACATT

Downstream 100 bases:

>100_bases
TCATACCGGAGAGTTTGCCAAGCAAGCTCTCCGACTTTTAGCTGAAAGGAACGCCCTTCCTTTCGCAGGATCAATGTAAA
GGAATCAGGGTTTTTAAAAG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRYQRHFKAARGEHGMSKNQHGR
NAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGGRGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKLTDDYPVFPISAVTRQGLRDL
LFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEISRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGM
GVDDALRARGAKDGDTIRLLEFEFEFID

Sequences:

>Translated_428_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRYQRHFKAARGEHGMSKNQHGR
NAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGGRGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKLTDDYPVFPISAVTRQGLRDL
LFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEISRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGM
GVDDALRARGAKDGDTIRLLEFEFEFID
>Mature_428_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRYQRHFKAARGEHGMSKNQHGR
NAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGGRGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKLTDDYPVFPISAVTRQGLRDL
LFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEISRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGM
GVDDALRARGAKDGDTIRLLEFEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=325, Percent_Identity=42.7692307692308, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI111955139, Length=377, Percent_Identity=36.0742705570292, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI111955063, Length=276, Percent_Identity=36.5942028985507, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=39.6694214876033, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=38.5826771653543, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=326, Percent_Identity=50.6134969325153, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.0579710144928, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790615, Length=173, Percent_Identity=28.9017341040462, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=41.6666666666667, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=31.7152103559871, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=37.2881355932203, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=30.9352517985612, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=38.1443298969072, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=40.4761904761905, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=36.5079365079365, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=29.0780141843972, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=339, Percent_Identity=42.1828908554572, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24585318, Length=307, Percent_Identity=40.7166123778502, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21356473, Length=126, Percent_Identity=38.8888888888889, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=37.7952755905512, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=35.15625, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=35.15625, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=35.15625, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47574; Mature: 47574

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
QRHFKAARGEHGMSKNQHGRNAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGG
HHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHC
AKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCEEEEEEEEECCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKL
EEEEECCCCCCCCCHHHHEEHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHC
TDDYPVFPISAVTRQGLRDLLFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEECCCCCCEEE
SRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGMGVDDALRARGAKDGDTIRLL
CCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC
>Mature Secondary Structure
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFKVDEGLSTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
QRHFKAARGEHGMSKNQHGRNAEDMVVKVPPGTVVIDDDTKQVIADLTEHGQEAVIAKGG
HHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHC
AKPKIADYHFTTLNPNLGMVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCEEEEEEEEECCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINKELEQYNLRLTERPQIIVANKMDMPDAEENLKAFKEKL
EEEEECCCCCCCCCHHHHEEHHHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHC
TDDYPVFPISAVTRQGLRDLLFEIADRLETTPEFPLYDEEDMAENRVMYKLEDEEAPFEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEECCCCCCEEE
SRDPDGTFVLSGAKLERLFKMTDFSRDESVKRFARQLRGMGVDDALRARGAKDGDTIRLL
CCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA