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The map label for this gene is hemD [H]

Identifier: 52786576

GI number: 52786576

Start: 2727344

End: 2728171

Strand: Reverse

Name: hemD [H]

Synonym: BLi02842

Alternate gene names: 52786576

Gene position: 2728171-2727344 (Counterclockwise)

Preceding gene: 52786578

Following gene: 52786573

Centisome position: 64.61

GC content: 52.42

Gene sequence:

>828_bases
TTGGGAAAAGGATTGAACGGCAGAAGAATTGCCATCGGAGCATCGCGAAAAACGGATGAAATGAGCACGCTGATCAAAAA
GCAAGGCGGGGTTCCCCTCATTCGCTCCCTTCAGGGTACCGTGTTTTTGGCCGAAAAAGAAGTAGGCCCTGATTTGCGTG
CCTTCGTTGAAACGGGAGCCGACTGGGTGATTTTCACGACCGGAATCGGGACGGAAACGCTTGTCAGCCTAGCTGAGAAA
CTTGGGATCGGAGAGCGCTATTTACAAGCGATCCGCAGGGCGAAAGCGGCATCGAGAGGCTACAAAACAATCGCCGCTTT
AAAAAAGCTCGGCATTACGCCCGTTGCGGCGGATGAAGACGGCACGACCAAGGGACTGATCGACTCGCTCCAATCCCACG
ATTTTTCCGGCAAACGGGTGATGGTTCAGCTCCACGGCGAAAACGCTCCGTCACTGCTTCAGTTTTTGGAAGAGAAAGGT
GCAGACGTTGTTCCGCTTCTGCCGTATCGGCATGTTGCTCCAGACCGGGAAACCGTCGCTTTATTGTGCAGCGAGATCAT
CAACCGTGAAGTGGATGCGGTTTGCTTTACAACGGCTGTCCAAGTCCGCTCGCTTTTTCATTTCGCGAAAGAAAACGGCT
ATGCGGAGAAAATTGTTCAATCTTTTCAAGACAGCGTGTTGGCGGCCGCTGTCGGAAAAGTGACGGCAGAAGCTTTAAGA
GAAGAAGGAGTCGAACGCCTTCTCGCTCCGGATCTCGAACGGATGGGAGCGATGATTGTGGAGCTAGCGCGGTTTTATGA
AACGGAAGAGGGGATAAGAACACAGTAA

Upstream 100 bases:

>100_bases
ACCTCCTGTTATTTTTAGATAATTCAATCATATCTCATTTGGAAGATGCTAGTAAACAGTTGCATTGACAAAAAACAGAT
TACGGAAAAGAGGGATTGCA

Downstream 100 bases:

>100_bases
GTGCGAAAGAAATCAGCAGATTGGGGTGTGGGAGTCTCCTTGGGGGCGTTGTGATGTTTTTTAAAGATGCAGACCCAAAA
GGAAAAAAGCCGAAGATGCA

Product: uroporphyrinogen-III synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MGKGLNGRRIAIGASRKTDEMSTLIKKQGGVPLIRSLQGTVFLAEKEVGPDLRAFVETGADWVIFTTGIGTETLVSLAEK
LGIGERYLQAIRRAKAASRGYKTIAALKKLGITPVAADEDGTTKGLIDSLQSHDFSGKRVMVQLHGENAPSLLQFLEEKG
ADVVPLLPYRHVAPDRETVALLCSEIINREVDAVCFTTAVQVRSLFHFAKENGYAEKIVQSFQDSVLAAAVGKVTAEALR
EEGVERLLAPDLERMGAMIVELARFYETEEGIRTQ

Sequences:

>Translated_275_residues
MGKGLNGRRIAIGASRKTDEMSTLIKKQGGVPLIRSLQGTVFLAEKEVGPDLRAFVETGADWVIFTTGIGTETLVSLAEK
LGIGERYLQAIRRAKAASRGYKTIAALKKLGITPVAADEDGTTKGLIDSLQSHDFSGKRVMVQLHGENAPSLLQFLEEKG
ADVVPLLPYRHVAPDRETVALLCSEIINREVDAVCFTTAVQVRSLFHFAKENGYAEKIVQSFQDSVLAAAVGKVTAEALR
EEGVERLLAPDLERMGAMIVELARFYETEEGIRTQ
>Mature_274_residues
GKGLNGRRIAIGASRKTDEMSTLIKKQGGVPLIRSLQGTVFLAEKEVGPDLRAFVETGADWVIFTTGIGTETLVSLAEKL
GIGERYLQAIRRAKAASRGYKTIAALKKLGITPVAADEDGTTKGLIDSLQSHDFSGKRVMVQLHGENAPSLLQFLEEKGA
DVVPLLPYRHVAPDRETVALLCSEIINREVDAVCFTTAVQVRSLFHFAKENGYAEKIVQSFQDSVLAAAVGKVTAEALRE
EGVERLLAPDLERMGAMIVELARFYETEEGIRTQ

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003754 [H]

Pfam domain/function: PF02602 HEM4 [H]

EC number: NA

Molecular weight: Translated: 29928; Mature: 29797

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGLNGRRIAIGASRKTDEMSTLIKKQGGVPLIRSLQGTVFLAEKEVGPDLRAFVETGA
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHCCC
DWVIFTTGIGTETLVSLAEKLGIGERYLQAIRRAKAASRGYKTIAALKKLGITPVAADED
CEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GTTKGLIDSLQSHDFSGKRVMVQLHGENAPSLLQFLEEKGADVVPLLPYRHVAPDRETVA
CCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHH
LLCSEIINREVDAVCFTTAVQVRSLFHFAKENGYAEKIVQSFQDSVLAAAVGKVTAEALR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEGVERLLAPDLERMGAMIVELARFYETEEGIRTQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKGLNGRRIAIGASRKTDEMSTLIKKQGGVPLIRSLQGTVFLAEKEVGPDLRAFVETGA
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHCCC
DWVIFTTGIGTETLVSLAEKLGIGERYLQAIRRAKAASRGYKTIAALKKLGITPVAADED
CEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GTTKGLIDSLQSHDFSGKRVMVQLHGENAPSLLQFLEEKGADVVPLLPYRHVAPDRETVA
CCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHH
LLCSEIINREVDAVCFTTAVQVRSLFHFAKENGYAEKIVQSFQDSVLAAAVGKVTAEALR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEGVERLLAPDLERMGAMIVELARFYETEEGIRTQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]