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The map label for this gene is cypA [H]

Identifier: 52786557

GI number: 52786557

Start: 2708396

End: 2709631

Strand: Reverse

Name: cypA [H]

Synonym: BLi02822

Alternate gene names: 52786557

Gene position: 2709631-2708396 (Counterclockwise)

Preceding gene: 52786558

Following gene: 52786556

Centisome position: 64.17

GC content: 45.71

Gene sequence:

>1236_bases
ATGTCTTCAAAACAAGAGGAGAGCTTCGCCATATTAACTGAGAGAGAATTGTCTTCTGCAGCATTTAAAGATGAGGCGTA
TGAATTTTACAAGCGATTACGCGCTTCCCGTCCTGTCTGTCCCGTATCGATGGGGGAGCTGGGCGAAGGCTGGCTCATTA
CGAGGTACGATGATGCGGTCCATATATTAAAGGATGCAAGAGTGAAAAAAAATTACGAAAATGCGTTTACCGAAGAAGAA
TTAGAGAACTTCTCCGCTCTGGAAAATGAAGAACCTTTATCAAAGCATATGCTCAACGCAGATCCCCCCGACCACGGCCG
TTTGCGGTCTCTTGTTCAGAAAGCATTTACTCCCCGGATGGTTTTACAGCTCGAAAACAGAATCCAAAAAATAGCTGATT
CCTTATTGGATCAAGTAGAACCGAATCATTCCATGAATCTTGTAGACGACTTCGCTTTCCCGCTGCCGATCATTGTCATC
AGCGAGATGCTTGGTATTCCGCTTGAAGATCGGCAAAAATTCAGAGTTTGGTCCCAGGCGGTTATTGATTTTTCTGACAC
GCCCGAAAGCCTGGAGGAATACAAGTATAAAATAGGCGAATTCGCTGAATACCTGGAATATTTGGTACGCAAAAAAAGGG
ACGAGCCGGCTGAGGATTTAGTCAGTGCATTAATTCAGGCAGAAAGCGAAGGAACGAAATTAAGCATAGAAGAGCTGTAT
GCGACGATTATGCTTCTTATCGTCGCAGGACATGAGACAACGGTAAACTTAATAACCAATATGACCTTGGCCTTGCTGAA
CCACCCTGAGCAACTGGAAAAGCTTCGCCAAAACGCAGATTTAATCGACTCAGCCATTGAAGAGGCGCTCAGATTTTACA
GCCCCGTGGAATTAACCACCCTCCGCTGGGCGGCCGAACCGTTTACATTGCACGGCCAGGAGATTAAGAGAAAAGATGTG
GTCATCATTTCATTAGCCTCGGCCAACCGCGATTATATGGTCTTTTCGAATGCCGACCGCTTTGATATTGAAAGAAAGGA
TAACCGCCACCTAGCCTTTGGCCATGGCAGCCATTTTTGCCTGGGCGCACCGCTTGCCCGATTGGAAGCCAAAATCGCCA
TTCAAACCTTGCTGCGCCGCTTTGAACATATAGAGATTAAAGGCGAAAGGGAGCAGATCAAATGGAAAGGCAACTTTTTG
ATGAGAGCTTTAGAAGAGCTGCCATTATCTTTTTAA

Upstream 100 bases:

>100_bases
TATTTGTGAATGAGTGGATGTGAACAGCCTAACGCATTATTTCGGTATACAATTCCGATGCAGGCTGTTATTTACAAAAA
CAGAGATGGAGGTTGGATGT

Downstream 100 bases:

>100_bases
ATGATGGGATTTGCGATCAGCTGTGATGTGCTATCTGCCATTTTGGCAAGAGAAGGTATGGAATGTTTTCATCTTGAAAA
TAGAACATCAGACGATGAGA

Product: CypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSSKQEESFAILTERELSSAAFKDEAYEFYKRLRASRPVCPVSMGELGEGWLITRYDDAVHILKDARVKKNYENAFTEEE
LENFSALENEEPLSKHMLNADPPDHGRLRSLVQKAFTPRMVLQLENRIQKIADSLLDQVEPNHSMNLVDDFAFPLPIIVI
SEMLGIPLEDRQKFRVWSQAVIDFSDTPESLEEYKYKIGEFAEYLEYLVRKKRDEPAEDLVSALIQAESEGTKLSIEELY
ATIMLLIVAGHETTVNLITNMTLALLNHPEQLEKLRQNADLIDSAIEEALRFYSPVELTTLRWAAEPFTLHGQEIKRKDV
VIISLASANRDYMVFSNADRFDIERKDNRHLAFGHGSHFCLGAPLARLEAKIAIQTLLRRFEHIEIKGEREQIKWKGNFL
MRALEELPLSF

Sequences:

>Translated_411_residues
MSSKQEESFAILTERELSSAAFKDEAYEFYKRLRASRPVCPVSMGELGEGWLITRYDDAVHILKDARVKKNYENAFTEEE
LENFSALENEEPLSKHMLNADPPDHGRLRSLVQKAFTPRMVLQLENRIQKIADSLLDQVEPNHSMNLVDDFAFPLPIIVI
SEMLGIPLEDRQKFRVWSQAVIDFSDTPESLEEYKYKIGEFAEYLEYLVRKKRDEPAEDLVSALIQAESEGTKLSIEELY
ATIMLLIVAGHETTVNLITNMTLALLNHPEQLEKLRQNADLIDSAIEEALRFYSPVELTTLRWAAEPFTLHGQEIKRKDV
VIISLASANRDYMVFSNADRFDIERKDNRHLAFGHGSHFCLGAPLARLEAKIAIQTLLRRFEHIEIKGEREQIKWKGNFL
MRALEELPLSF
>Mature_410_residues
SSKQEESFAILTERELSSAAFKDEAYEFYKRLRASRPVCPVSMGELGEGWLITRYDDAVHILKDARVKKNYENAFTEEEL
ENFSALENEEPLSKHMLNADPPDHGRLRSLVQKAFTPRMVLQLENRIQKIADSLLDQVEPNHSMNLVDDFAFPLPIIVIS
EMLGIPLEDRQKFRVWSQAVIDFSDTPESLEEYKYKIGEFAEYLEYLVRKKRDEPAEDLVSALIQAESEGTKLSIEELYA
TIMLLIVAGHETTVNLITNMTLALLNHPEQLEKLRQNADLIDSAIEEALRFYSPVELTTLRWAAEPFTLHGQEIKRKDVV
IISLASANRDYMVFSNADRFDIERKDNRHLAFGHGSHFCLGAPLARLEAKIAIQTLLRRFEHIEIKGEREQIKWKGNFLM
RALEELPLSF

Specific function: Unknown

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI310125128, Length=162, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI14550409, Length=162, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI310125130, Length=162, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI190570174, Length=162, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17552522, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557254, Length=210, Percent_Identity=29.5238095238095, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982956, Length=210, Percent_Identity=25.2380952380952, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540354, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532670, Length=210, Percent_Identity=24.7619047619048, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17933518, Length=215, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 47343; Mature: 47211

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKQEESFAILTERELSSAAFKDEAYEFYKRLRASRPVCPVSMGELGEGWLITRYDDAV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHH
HILKDARVKKNYENAFTEEELENFSALENEEPLSKHMLNADPPDHGRLRSLVQKAFTPRM
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCHHH
VLQLENRIQKIADSLLDQVEPNHSMNLVDDFAFPLPIIVISEMLGIPLEDRQKFRVWSQA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHH
VIDFSDTPESLEEYKYKIGEFAEYLEYLVRKKRDEPAEDLVSALIQAESEGTKLSIEELY
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHH
ATIMLLIVAGHETTVNLITNMTLALLNHPEQLEKLRQNADLIDSAIEEALRFYSPVELTT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LRWAAEPFTLHGQEIKRKDVVIISLASANRDYMVFSNADRFDIERKDNRHLAFGHGSHFC
EEECCCCCEECCHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEECCCCCEE
LGAPLARLEAKIAIQTLLRRFEHIEIKGEREQIKWKGNFLMRALEELPLSF
CCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSKQEESFAILTERELSSAAFKDEAYEFYKRLRASRPVCPVSMGELGEGWLITRYDDAV
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHH
HILKDARVKKNYENAFTEEELENFSALENEEPLSKHMLNADPPDHGRLRSLVQKAFTPRM
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCHHH
VLQLENRIQKIADSLLDQVEPNHSMNLVDDFAFPLPIIVISEMLGIPLEDRQKFRVWSQA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHH
VIDFSDTPESLEEYKYKIGEFAEYLEYLVRKKRDEPAEDLVSALIQAESEGTKLSIEELY
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHH
ATIMLLIVAGHETTVNLITNMTLALLNHPEQLEKLRQNADLIDSAIEEALRFYSPVELTT
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LRWAAEPFTLHGQEIKRKDVVIISLASANRDYMVFSNADRFDIERKDNRHLAFGHGSHFC
EEECCCCCEECCHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEECCCCCEE
LGAPLARLEAKIAIQTLLRRFEHIEIKGEREQIKWKGNFLMRALEELPLSF
CCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]