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The map label for this gene is yqgP [H]

Identifier: 52786400

GI number: 52786400

Start: 2569926

End: 2571464

Strand: Reverse

Name: yqgP [H]

Synonym: BLi02664

Alternate gene names: 52786400

Gene position: 2571464-2569926 (Counterclockwise)

Preceding gene: 52786401

Following gene: 52786399

Centisome position: 60.9

GC content: 50.62

Gene sequence:

>1539_bases
ATGTATTCAATCGATTATTTGTATTGGAATTTCATCGGGAACCTTTTAGACAGGGATTTTGAGCTTGTGCAGGCACCTGC
TTCATTCGGAGAAGCCTGGCTTGAAGCGAGGGGGAGCGCGCCGTATGATTTGGTTCGCGTTTTCCGGAAGGATATCGACT
TCAGACAGGATCTCGTCCGCGACCTGGAATCTCTTTATGAAAGGGCGGAGCGCCTGAGAGCAGCATCAGGTCAGCGAAAG
CTCTCGATATTGAATGTCTATTTGTCGCAGGAAGCGCCTGTAGATGAGTGGGAAGATGTTGTCGGTCATCCGGTCGCAGA
TAAGCGGATCAGCATCGTGCCGGTTTTTATTGATCACGCTTCGGCTGAAGAAGGATTACGCAAACTCGCCGTGGCTTTAA
ACATGGAGCCGGATGAGCTGACAGGCCAAATGCAGGATGCCGGATACGAAAATGTGGAAGAGAAGAGAGCCGAAGTATTG
GCAGCGGCTAAAGCAAGAGAAGAAGAAAGGCGGCGGGAAGCGGCTGTATTTGAGAAAGGCAAACCGATGTTTACCTGGAT
TTTCGCAGTGCTTCAAGTCTTCATGTTTCTGCTTCTGGAAATGTCGGGCGGCAGCCAGAATACCGAAACGCTCGTCCGGT
TCGGGGCGAAGGAAAACAGCCTCCTGTTAGCCGGGGAATGGTGGCGGCTAGTCACGCCGATCGTTCTTCATATCGGATTG
GTCCATCTCATGTTTAATACATTTGCATTATTGTCTGTTGGAGCCGCAGCAGAAAGGGTGTTTGGATCATTCCGCTTTCT
TGTCATATACATATCAGCCGGGATTTTTGGATCGATCGGCAGCTTTCTGTTCAGTCCGTATCCGTCTGCAGGGGCTTCGG
GAGCCATCTTCGGTTGCTTGGGAGCCCTTTTGTACCTGGCTTTTTCAAACCGGAAAGCTTTTTTAAAAACGATCGGAACA
AATATCATTGTGATCATCATTCTGAACCTCGGCCTCGGTTTCACCATTTCAAATGTTGACAATGCTGGCCATATCGGCGG
ATTGATCGGCGGTCTCCTGACGGCCTTGGCGGTCGGAATCCCCGGAAAAAAAAGGCCGCTCCAGCGGCTGGCAGGCTGGG
TCCTCATCTTTGTCATCGGAGGAGGGGCCCTGTACTTTGGGACACATTCGGCTCCGGTGCAGGAAAATGCCATGCTGCAT
CAGGCGGCGAAATGGTATGAAGAGGGAGAGTATGAAAAAGTAAAGGATGCTTTGAAGGAAGCGGGCTCAAAACCGGACGC
TTCCAGCGACACTTTAAGGCTGCTCGCTTATTCCGAAATTCGGCTCGGCGAGTATGAAAACGCCGAGAAAAGGTTTGAGG
CCGTCGTTGAAAAAGATCCATCGGACCACGCCTCTCTCTATAGTCTTGCCTGGCTTTATACCCAAAGAGGCGAGCTTGCC
AAAGCCGAGCAGTCCATTGAAAGAGCGTTGGCAGAAAAGCCTGATGAAGAGATGTATAAAAAGCTTCGGGACGAAATAAA
GAAAGAAAGCGCCCGGTAA

Upstream 100 bases:

>100_bases
TCTGAATCCCGTTTGAAAACGGGATTTTTTAAAGCTCTTAAAAGACGCAGAGTGTCGCGTTTCCTGTTATAATGAACAAA
AACAATTGTGGAGCGTCGGT

Downstream 100 bases:

>100_bases
TCAAGTATGAAAAGCTTCCGTTATGTTAAAAATGGTCTTTAGAACAGACTCATTTGACGGGAGCTTTTAATATACAATGA
AAAAAAAGCATGCGGTCCAA

Product: YqgP

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MYSIDYLYWNFIGNLLDRDFELVQAPASFGEAWLEARGSAPYDLVRVFRKDIDFRQDLVRDLESLYERAERLRAASGQRK
LSILNVYLSQEAPVDEWEDVVGHPVADKRISIVPVFIDHASAEEGLRKLAVALNMEPDELTGQMQDAGYENVEEKRAEVL
AAAKAREEERRREAAVFEKGKPMFTWIFAVLQVFMFLLLEMSGGSQNTETLVRFGAKENSLLLAGEWWRLVTPIVLHIGL
VHLMFNTFALLSVGAAAERVFGSFRFLVIYISAGIFGSIGSFLFSPYPSAGASGAIFGCLGALLYLAFSNRKAFLKTIGT
NIIVIIILNLGLGFTISNVDNAGHIGGLIGGLLTALAVGIPGKKRPLQRLAGWVLIFVIGGGALYFGTHSAPVQENAMLH
QAAKWYEEGEYEKVKDALKEAGSKPDASSDTLRLLAYSEIRLGEYENAEKRFEAVVEKDPSDHASLYSLAWLYTQRGELA
KAEQSIERALAEKPDEEMYKKLRDEIKKESAR

Sequences:

>Translated_512_residues
MYSIDYLYWNFIGNLLDRDFELVQAPASFGEAWLEARGSAPYDLVRVFRKDIDFRQDLVRDLESLYERAERLRAASGQRK
LSILNVYLSQEAPVDEWEDVVGHPVADKRISIVPVFIDHASAEEGLRKLAVALNMEPDELTGQMQDAGYENVEEKRAEVL
AAAKAREEERRREAAVFEKGKPMFTWIFAVLQVFMFLLLEMSGGSQNTETLVRFGAKENSLLLAGEWWRLVTPIVLHIGL
VHLMFNTFALLSVGAAAERVFGSFRFLVIYISAGIFGSIGSFLFSPYPSAGASGAIFGCLGALLYLAFSNRKAFLKTIGT
NIIVIIILNLGLGFTISNVDNAGHIGGLIGGLLTALAVGIPGKKRPLQRLAGWVLIFVIGGGALYFGTHSAPVQENAMLH
QAAKWYEEGEYEKVKDALKEAGSKPDASSDTLRLLAYSEIRLGEYENAEKRFEAVVEKDPSDHASLYSLAWLYTQRGELA
KAEQSIERALAEKPDEEMYKKLRDEIKKESAR
>Mature_512_residues
MYSIDYLYWNFIGNLLDRDFELVQAPASFGEAWLEARGSAPYDLVRVFRKDIDFRQDLVRDLESLYERAERLRAASGQRK
LSILNVYLSQEAPVDEWEDVVGHPVADKRISIVPVFIDHASAEEGLRKLAVALNMEPDELTGQMQDAGYENVEEKRAEVL
AAAKAREEERRREAAVFEKGKPMFTWIFAVLQVFMFLLLEMSGGSQNTETLVRFGAKENSLLLAGEWWRLVTPIVLHIGL
VHLMFNTFALLSVGAAAERVFGSFRFLVIYISAGIFGSIGSFLFSPYPSAGASGAIFGCLGALLYLAFSNRKAFLKTIGT
NIIVIIILNLGLGFTISNVDNAGHIGGLIGGLLTALAVGIPGKKRPLQRLAGWVLIFVIGGGALYFGTHSAPVQENAMLH
QAAKWYEEGEYEKVKDALKEAGSKPDASSDTLRLLAYSEIRLGEYENAEKRFEAVVEKDPSDHASLYSLAWLYTQRGELA
KAEQSIERALAEKPDEEMYKKLRDEIKKESAR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Caenorhabditis elegans, GI133901888, Length=137, Percent_Identity=32.1167883211679, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532986, Length=137, Percent_Identity=32.1167883211679, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534507, Length=138, Percent_Identity=29.7101449275362, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 56994; Mature: 56994

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSIDYLYWNFIGNLLDRDFELVQAPASFGEAWLEARGSAPYDLVRVFRKDIDFRQDLVR
CCEEHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHH
DLESLYERAERLRAASGQRKLSILNVYLSQEAPVDEWEDVVGHPVADKRISIVPVFIDHA
HHHHHHHHHHHHHHHCCCCCEEHHEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEEEECC
SAEEGLRKLAVALNMEPDELTGQMQDAGYENVEEKRAEVLAAAKAREEERRREAAVFEKG
CHHHHHHHHHHHHCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPMFTWIFAVLQVFMFLLLEMSGGSQNTETLVRFGAKENSLLLAGEWWRLVTPIVLHIGL
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHH
VHLMFNTFALLSVGAAAERVFGSFRFLVIYISAGIFGSIGSFLFSPYPSAGASGAIFGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
GALLYLAFSNRKAFLKTIGTNIIVIIILNLGLGFTISNVDNAGHIGGLIGGLLTALAVGI
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCC
PGKKRPLQRLAGWVLIFVIGGGALYFGTHSAPVQENAMLHQAAKWYEEGEYEKVKDALKE
CCCCCHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGSKPDASSDTLRLLAYSEIRLGEYENAEKRFEAVVEKDPSDHASLYSLAWLYTQRGELA
CCCCCCCCCCCEEHEEHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
KAEQSIERALAEKPDEEMYKKLRDEIKKESAR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYSIDYLYWNFIGNLLDRDFELVQAPASFGEAWLEARGSAPYDLVRVFRKDIDFRQDLVR
CCEEHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHH
DLESLYERAERLRAASGQRKLSILNVYLSQEAPVDEWEDVVGHPVADKRISIVPVFIDHA
HHHHHHHHHHHHHHHCCCCCEEHHEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEEEECC
SAEEGLRKLAVALNMEPDELTGQMQDAGYENVEEKRAEVLAAAKAREEERRREAAVFEKG
CHHHHHHHHHHHHCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPMFTWIFAVLQVFMFLLLEMSGGSQNTETLVRFGAKENSLLLAGEWWRLVTPIVLHIGL
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHH
VHLMFNTFALLSVGAAAERVFGSFRFLVIYISAGIFGSIGSFLFSPYPSAGASGAIFGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
GALLYLAFSNRKAFLKTIGTNIIVIIILNLGLGFTISNVDNAGHIGGLIGGLLTALAVGI
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCC
PGKKRPLQRLAGWVLIFVIGGGALYFGTHSAPVQENAMLHQAAKWYEEGEYEKVKDALKE
CCCCCHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGSKPDASSDTLRLLAYSEIRLGEYENAEKRFEAVVEKDPSDHASLYSLAWLYTQRGELA
CCCCCCCCCCCEEHEEHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
KAEQSIERALAEKPDEEMYKKLRDEIKKESAR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]