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The map label for this gene is glcK [H]

Identifier: 52786397

GI number: 52786397

Start: 2567098

End: 2568072

Strand: Reverse

Name: glcK [H]

Synonym: BLi02660

Alternate gene names: 52786397

Gene position: 2568072-2567098 (Counterclockwise)

Preceding gene: 52786398

Following gene: 52786396

Centisome position: 60.82

GC content: 52.51

Gene sequence:

>975_bases
ATGAATGACAGCTGGCTGGTCGGGGTCGACCTTGGAGGAACAACAGTAAAACTCGCTTTTGTAAGCGCTTATGGCGAAAT
CCTGCACAAGTGGGAAATCCCGACCGATAAATCAGGGAAAACGGTTACGGTAAGCATCGCGAAAGCCATCGACAGCAAAT
TGAACGAGCTCGGCAAACCGAAGCACATCTTAAAATGGATCGGCATGGGCGCTCCCGGACCCGTCAATACGGAGACCGGC
ATCGTTTATAAAACGACGAATATGGGCTGGGAAAACTACCCGTTGAAAGACCATCTGGAAGCAGAGACAGGGATAGCTGC
GGTCATTGAAAATGACGCGAACATCGCAGCTCTCGGCGAAATGTGGAAGGGAGCGGGAGACGGCGCGAAGGATTTGATTC
TTGTTACATTGGGAACGGGCGTTGGAGGCGGCATTATTGTAAACGGGGAAATCGTCCGCGGGCAAAACGGAGCAGGCGGT
GAAATCGGCCACATCTGTTCTGTTCCAGAAGGCGGAGCGCCGTGCAACTGCGGAAAAAGCGGCTGTATCGAAACGATCGC
TTCGGCTACCGGCATCGTCAGGATTGCCAAAGAAAAAATAGAATCTGACCATCGAGATACAAGCTTGCGTGAATGTCTGG
ACATAACGGCGCGCGACATCTTTGAAGCCGCCAGAAAAAACGATCCTGTTGCCGGCGAAGTCGTCGATTATGTGGCGGGT
CATTTAGGAATGGTCCTCGCTAACTTGGCGAGCTCGCTTAATCCTTCAAAGATCGTAATCGGCGGAGGCGTGTCAAAAGC
GGGAGAAATCCTGCGCTCCAAAGTTGAACAATCTTTCAAGCGCTTTGTATTCCCGCGGGCCGGCGAGGCGGCTGAGATCG
TAATCGCTTCACTTGGAAACGACGCAGGCGTGATCGGCGGTGCATGGATCGCAAAAAACCAATGGCTGAAAAGCCAGGCG
CAGCCTGTTTTATAA

Upstream 100 bases:

>100_bases
TTTGATAGAAAAAGAACAATGGGTTCAAGGTGTTTCAATTTTGCAGAATGAACTCACAAATATAAAGAGAAAATAAAACA
GGGATTAGAGGGGGATCAGT

Downstream 100 bases:

>100_bases
AGCATTTTCGGACCGCTTTGCAGCATTGTTAACACTTTTAAGCCAATGTGAAAAATGATTGATTTTTTTGTACAGACAGG
TTAAGATATGATTTAGTAAT

Product: GlcK

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNDSWLVGVDLGGTTVKLAFVSAYGEILHKWEIPTDKSGKTVTVSIAKAIDSKLNELGKPKHILKWIGMGAPGPVNTETG
IVYKTTNMGWENYPLKDHLEAETGIAAVIENDANIAALGEMWKGAGDGAKDLILVTLGTGVGGGIIVNGEIVRGQNGAGG
EIGHICSVPEGGAPCNCGKSGCIETIASATGIVRIAKEKIESDHRDTSLRECLDITARDIFEAARKNDPVAGEVVDYVAG
HLGMVLANLASSLNPSKIVIGGGVSKAGEILRSKVEQSFKRFVFPRAGEAAEIVIASLGNDAGVIGGAWIAKNQWLKSQA
QPVL

Sequences:

>Translated_324_residues
MNDSWLVGVDLGGTTVKLAFVSAYGEILHKWEIPTDKSGKTVTVSIAKAIDSKLNELGKPKHILKWIGMGAPGPVNTETG
IVYKTTNMGWENYPLKDHLEAETGIAAVIENDANIAALGEMWKGAGDGAKDLILVTLGTGVGGGIIVNGEIVRGQNGAGG
EIGHICSVPEGGAPCNCGKSGCIETIASATGIVRIAKEKIESDHRDTSLRECLDITARDIFEAARKNDPVAGEVVDYVAG
HLGMVLANLASSLNPSKIVIGGGVSKAGEILRSKVEQSFKRFVFPRAGEAAEIVIASLGNDAGVIGGAWIAKNQWLKSQA
QPVL
>Mature_324_residues
MNDSWLVGVDLGGTTVKLAFVSAYGEILHKWEIPTDKSGKTVTVSIAKAIDSKLNELGKPKHILKWIGMGAPGPVNTETG
IVYKTTNMGWENYPLKDHLEAETGIAAVIENDANIAALGEMWKGAGDGAKDLILVTLGTGVGGGIIVNGEIVRGQNGAGG
EIGHICSVPEGGAPCNCGKSGCIETIASATGIVRIAKEKIESDHRDTSLRECLDITARDIFEAARKNDPVAGEVVDYVAG
HLGMVLANLASSLNPSKIVIGGGVSKAGEILRSKVEQSFKRFVFPRAGEAAEIVIASLGNDAGVIGGAWIAKNQWLKSQA
QPVL

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=264, Percent_Identity=30.3030303030303, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI298566315, Length=264, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4885285, Length=264, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI190014632, Length=264, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1786891, Length=283, Percent_Identity=31.4487632508834, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87081733, Length=316, Percent_Identity=33.2278481012658, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787878, Length=269, Percent_Identity=30.1115241635688, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787363, Length=313, Percent_Identity=25.8785942492013, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082127, Length=253, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082230, Length=263, Percent_Identity=28.1368821292776, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790522, Length=318, Percent_Identity=27.0440251572327, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33832; Mature: 33832

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSWLVGVDLGGTTVKLAFVSAYGEILHKWEIPTDKSGKTVTVSIAKAIDSKLNELGKP
CCCCEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHCCCH
KHILKWIGMGAPGPVNTETGIVYKTTNMGWENYPLKDHLEAETGIAAVIENDANIAALGE
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCEEEEEECCCCEEHHHH
MWKGAGDGAKDLILVTLGTGVGGGIIVNGEIVRGQNGAGGEIGHICSVPEGGAPCNCGKS
HHCCCCCCCCEEEEEEECCCCCCCEEEECEEEECCCCCCCCCCCEECCCCCCCCCCCCCH
GCIETIASATGIVRIAKEKIESDHRDTSLRECLDITARDIFEAARKNDPVAGEVVDYVAG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
HLGMVLANLASSLNPSKIVIGGGVSKAGEILRSKVEQSFKRFVFPRAGEAAEIVIASLGN
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCC
DAGVIGGAWIAKNQWLKSQAQPVL
CCCEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDSWLVGVDLGGTTVKLAFVSAYGEILHKWEIPTDKSGKTVTVSIAKAIDSKLNELGKP
CCCCEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHCCCH
KHILKWIGMGAPGPVNTETGIVYKTTNMGWENYPLKDHLEAETGIAAVIENDANIAALGE
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCEEEEEECCCCEEHHHH
MWKGAGDGAKDLILVTLGTGVGGGIIVNGEIVRGQNGAGGEIGHICSVPEGGAPCNCGKS
HHCCCCCCCCEEEEEEECCCCCCCEEEECEEEECCCCCCCCCCCEECCCCCCCCCCCCCH
GCIETIASATGIVRIAKEKIESDHRDTSLRECLDITARDIFEAARKNDPVAGEVVDYVAG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
HLGMVLANLASSLNPSKIVIGGGVSKAGEILRSKVEQSFKRFVFPRAGEAAEIVIASLGN
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCC
DAGVIGGAWIAKNQWLKSQAQPVL
CCCEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9620975 [H]