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The map label for this gene is xseA

Identifier: 52786339

GI number: 52786339

Start: 2520927

End: 2522276

Strand: Reverse

Name: xseA

Synonym: BLi02601

Alternate gene names: 52786339

Gene position: 2522276-2520927 (Counterclockwise)

Preceding gene: 52786340

Following gene: 52786338

Centisome position: 59.73

GC content: 47.19

Gene sequence:

>1350_bases
ATGAGTGAAATATCATTTGTCACGGTCACGGCTTTGACAAAATATATTAAGCGCAAATTTGACGTGGACCCTCATCTTGA
AGATATTTGGATCAAGGGCGAGCTGTCAAATGTTAAAATACATAGCAGAGGCCATATTTATTTCACACTGAAAGATGATA
ACGCCCGCATCCAATCCGTCATGTTCGCCAGACAAAACAGGAATCTCGCCTTTACCCCTGAAAACGGGATGAAAGTATTG
GTGAGAGGCGGCATTTCGGTATATGAACCGAGCGGCAGCTATCAGCTTTATGCAAAAGAAATCCAGCCGGACGGCATAGG
TGCGCTTCATCTCGCGTATGAGGAACTTAAGAAAAAGCTATCGCAAGAAGGCTTATTTGATGAAAAATACAAGAAACCCA
TCCCCGCGTTCCCATCCGTCGTCGGTGTTGTCACGTCTCCAACTGGAGCGGCTGTACGCGATGTGATCACCACCATTAAA
AGAAGATATCCCCTTGTAAAAGTGATCGTCCTTCCTACGCTCGTTCAAGGAGTAAACGCGGGCGAGTCCATCGTAAGCAG
CATTGAAGAGGCTAACCGCAGAGACTTATGCGATGTATTAATCGTCGGTCGAGGAGGAGGATCGATCGAAGAGCTGTGGG
CATTTAACGAAGAGGCCGTCGCCAGGGCCATTTTTTCTTCTGACATTCCGATCATTTCTGCCGTCGGGCATGAAACGGAT
TTTACAATCAGCGATTTTGTCGCCGATTTGCGCGCGGCAACCCCGACAGGAGCGGCCGAACTGGCCGTACCTAATATGCT
TGATTTGCTGGAGCGTCTGAAAACGCTCGAAGCGAGAATGACAAAATCGATGCAGCAGGACTTAAAAAAGCGGCAGGAGC
GGGTGAAAAACCTTCAGTCCTCCTATGCCTTCCGATACCCGAAGCGGCTATATGCCCAAAAGGAACAGGAATTCGACCTG
ATATTCGACCGTTTCCAAAAACAGCTGGCGATGACCGTCGACCGCAAAAAACAAAAACTGAACGAACAGACATACAAGCT
GGAGATGCTTCATCCCGAGGAGCAGCTTAAACAAGCGCGAAAAAGGCATGAAGAGCAAACAGTCCGGCTGAAGCGGAATA
TGAAAGTGCAGCTGAAGCAGATTCACTCGCAGTTTCAAACGGTTCTTGGTAAACTGAATGCATTAAGCCCTCTCCAAGTG
ATGGAAAGAGGGTACAGTTTGACATATAAAGAAAACGAATTGATTAAAAGTATTGAACAGGTTCATGAAAAAGACGAGAT
CCGCGTCACATTAAACGATGGGACGCTGACCTGTGAGGTACTGCAAAAGAGAGGCGAAACAAATGGCTGA

Upstream 100 bases:

>100_bases
GCGAAGCGTACAATTCAACTTTAATGTACAGCCGTTCATCCGCCTGGTCTCGCGCCGGCGGATGAACGTTCTTGTGCCTT
CTTAGAAAGGAGACTGTGCC

Downstream 100 bases:

>100_bases
AGAAAACAAAACAAACCGGGATGACCTGACATTTGAAGAGGCGATGAAAGGTTTGGAACAGATCGTATCAAAGCTTGAAG
AAGGGGACGTGCCTTTGGAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSEISFVTVTALTKYIKRKFDVDPHLEDIWIKGELSNVKIHSRGHIYFTLKDDNARIQSVMFARQNRNLAFTPENGMKVL
VRGGISVYEPSGSYQLYAKEIQPDGIGALHLAYEELKKKLSQEGLFDEKYKKPIPAFPSVVGVVTSPTGAAVRDVITTIK
RRYPLVKVIVLPTLVQGVNAGESIVSSIEEANRRDLCDVLIVGRGGGSIEELWAFNEEAVARAIFSSDIPIISAVGHETD
FTISDFVADLRAATPTGAAELAVPNMLDLLERLKTLEARMTKSMQQDLKKRQERVKNLQSSYAFRYPKRLYAQKEQEFDL
IFDRFQKQLAMTVDRKKQKLNEQTYKLEMLHPEEQLKQARKRHEEQTVRLKRNMKVQLKQIHSQFQTVLGKLNALSPLQV
MERGYSLTYKENELIKSIEQVHEKDEIRVTLNDGTLTCEVLQKRGETNG

Sequences:

>Translated_449_residues
MSEISFVTVTALTKYIKRKFDVDPHLEDIWIKGELSNVKIHSRGHIYFTLKDDNARIQSVMFARQNRNLAFTPENGMKVL
VRGGISVYEPSGSYQLYAKEIQPDGIGALHLAYEELKKKLSQEGLFDEKYKKPIPAFPSVVGVVTSPTGAAVRDVITTIK
RRYPLVKVIVLPTLVQGVNAGESIVSSIEEANRRDLCDVLIVGRGGGSIEELWAFNEEAVARAIFSSDIPIISAVGHETD
FTISDFVADLRAATPTGAAELAVPNMLDLLERLKTLEARMTKSMQQDLKKRQERVKNLQSSYAFRYPKRLYAQKEQEFDL
IFDRFQKQLAMTVDRKKQKLNEQTYKLEMLHPEEQLKQARKRHEEQTVRLKRNMKVQLKQIHSQFQTVLGKLNALSPLQV
MERGYSLTYKENELIKSIEQVHEKDEIRVTLNDGTLTCEVLQKRGETNG
>Mature_448_residues
SEISFVTVTALTKYIKRKFDVDPHLEDIWIKGELSNVKIHSRGHIYFTLKDDNARIQSVMFARQNRNLAFTPENGMKVLV
RGGISVYEPSGSYQLYAKEIQPDGIGALHLAYEELKKKLSQEGLFDEKYKKPIPAFPSVVGVVTSPTGAAVRDVITTIKR
RYPLVKVIVLPTLVQGVNAGESIVSSIEEANRRDLCDVLIVGRGGGSIEELWAFNEEAVARAIFSSDIPIISAVGHETDF
TISDFVADLRAATPTGAAELAVPNMLDLLERLKTLEARMTKSMQQDLKKRQERVKNLQSSYAFRYPKRLYAQKEQEFDLI
FDRFQKQLAMTVDRKKQKLNEQTYKLEMLHPEEQLKQARKRHEEQTVRLKRNMKVQLKQIHSQFQTVLGKLNALSPLQVM
ERGYSLTYKENELIKSIEQVHEKDEIRVTLNDGTLTCEVLQKRGETNG

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=40.5895691609977, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_BACLD (Q65HI9)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079754.1
- RefSeq:   YP_092168.1
- STRING:   Q65HI9
- EnsemblBacteria:   EBBACT00000054877
- EnsemblBacteria:   EBBACT00000062306
- GeneID:   3029515
- GeneID:   3100911
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02601
- KEGG:   bli:BL01526
- NMPDR:   fig|279010.5.peg.446
- eggNOG:   COG1570
- GeneTree:   EBGT00050000001906
- HOGENOM:   HBG634411
- OMA:   ANERREC
- ProtClustDB:   PRK00286
- BioCyc:   BLIC279010-1:BLI02601-MONOMER
- BioCyc:   BLIC279010:BL01526-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51170; Mature: 51038

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEISFVTVTALTKYIKRKFDVDPHLEDIWIKGELSNVKIHSRGHIYFTLKDDNARIQSV
CCCCCEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCEEEEEEECCCHHHHHH
MFARQNRNLAFTPENGMKVLVRGGISVYEPSGSYQLYAKEIQPDGIGALHLAYEELKKKL
HHHHCCCCEEECCCCCCEEEEECCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
SQEGLFDEKYKKPIPAFPSVVGVVTSPTGAAVRDVITTIKRRYPLVKVIVLPTLVQGVNA
HHCCCCCHHHCCCCCCCCHHHHEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GESIVSSIEEANRRDLCDVLIVGRGGGSIEELWAFNEEAVARAIFSSDIPIISAVGHETD
CHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCC
FTISDFVADLRAATPTGAAELAVPNMLDLLERLKTLEARMTKSMQQDLKKRQERVKNLQS
CCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYAFRYPKRLYAQKEQEFDLIFDRFQKQLAMTVDRKKQKLNEQTYKLEMLHPEEQLKQAR
HHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCHHHHHHHH
KRHEEQTVRLKRNMKVQLKQIHSQFQTVLGKLNALSPLQVMERGYSLTYKENELIKSIEQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECHHHHHHHHHH
VHEKDEIRVTLNDGTLTCEVLQKRGETNG
HCCCCCEEEEECCCEEEHHHHHHCCCCCC
>Mature Secondary Structure 
SEISFVTVTALTKYIKRKFDVDPHLEDIWIKGELSNVKIHSRGHIYFTLKDDNARIQSV
CCCCEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCEEEEEEECCCHHHHHH
MFARQNRNLAFTPENGMKVLVRGGISVYEPSGSYQLYAKEIQPDGIGALHLAYEELKKKL
HHHHCCCCEEECCCCCCEEEEECCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
SQEGLFDEKYKKPIPAFPSVVGVVTSPTGAAVRDVITTIKRRYPLVKVIVLPTLVQGVNA
HHCCCCCHHHCCCCCCCCHHHHEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GESIVSSIEEANRRDLCDVLIVGRGGGSIEELWAFNEEAVARAIFSSDIPIISAVGHETD
CHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCC
FTISDFVADLRAATPTGAAELAVPNMLDLLERLKTLEARMTKSMQQDLKKRQERVKNLQS
CCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYAFRYPKRLYAQKEQEFDLIFDRFQKQLAMTVDRKKQKLNEQTYKLEMLHPEEQLKQAR
HHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCHHHHHHHH
KRHEEQTVRLKRNMKVQLKQIHSQFQTVLGKLNALSPLQVMERGYSLTYKENELIKSIEQ
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECHHHHHHHHHH
VHEKDEIRVTLNDGTLTCEVLQKRGETNG
HCCCCCEEEEECCCEEEHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA