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The map label for this gene is coaA [H]

Identifier: 52786278

GI number: 52786278

Start: 2458934

End: 2459902

Strand: Reverse

Name: coaA [H]

Synonym: BLi02540

Alternate gene names: 52786278

Gene position: 2459902-2458934 (Counterclockwise)

Preceding gene: 52786279

Following gene: 52786277

Centisome position: 58.26

GC content: 46.13

Gene sequence:

>969_bases
GTGAGAATAGTGGCGAATCAGGATTTGAATTTGCACACGTTATATACGAGTCATACCCGTGATGCCTGGGCAAATCTCGG
CGGGCATATGTCGGTAAAGATGACCGAAGAGGAAGTAAAGAAGCTTGAAGGTTTAAATGACTATCTGTCTTTGGAAGAAG
TCGAAACCGTTTATGTTCCGCTGGCGAGGCTGCTTTATTTACACCGGGCAACTCAATATGAACGGAACACCCGGGTAAAC
GGTTTTTTGAATCATCCTCACGCGGCCAAGATTCCGTTTATCATCGGGATTGCCGGAAGCGTCGCGGTTGGAAAAAGCAC
GACGGCCCGCATCATTCAGACTGTGCTCTCCCGTTTGCAGGAACGGCTGAAAGTCAGTCTGATCACAACCGACGGTTTTC
TTTATCCTAATGCGGTTCTGACAGAAAAGCAGATGATGTCGAGGAAAGGGTTTCCCGAAAGCTATGATGTCAAAGCGCTG
CTTGAGTTTTTGAACGATTTAAAATCAGGAAAGGAAATTGTCCACGCACCCGTTTATTCCCATCTAACGTATGACAGATT
GGAAGGGGTTTATGAAACGGTAGAACAAGCGGATATCGTGATCATCGAAGGCGTTAATGTGCTGCAGACACCGACGATCG
AAGACGACCGTACAAAACCGCGGGTTTTCGTTTCCGATTTTTTTGACTTCTCGATTTATGTGGATGCCGAAGAAGACCTC
ATTATCAAATGGTATCTTGAACGCTTTCGCATGCTCAGGGAGACGGCTTTTCAAGATCCGAGTTCTTATTTCCATAAATT
CAAAGACCTCGCGGACGAAGAAGCGGACCATATGGCAAAGTCAATATGGGAGACCGTCAACCGTCCGAATTTGTATGAGA
ACATTCTGCCTACAAAATTCCGGTCTGATTTAATCTTGAGAAAAGGCGAAGGCCACAAGGTGGAAGAGATTTTGGTCAGA
CGGGTATAG

Upstream 100 bases:

>100_bases
ACGTTGTTCCTCGTAAATATTCGAAAAATTCTATATAATAATAAAGCGGTCTCAGAATTCATGCACTTTTTTAAGTAAAC
AGCGTTTGAACAGAGGGCAG

Downstream 100 bases:

>100_bases
AAGAGGAGGCTTGCATGATCCATCATATTGAACTGTACGTTTCAGATTTGGAAGCGTCGAAGCGCTTTTGGGGCTGGTTT
CTCGGGGAGCTCGGCTATGA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRIVANQDLNLHTLYTSHTRDAWANLGGHMSVKMTEEEVKKLEGLNDYLSLEEVETVYVPLARLLYLHRATQYERNTRVN
GFLNHPHAAKIPFIIGIAGSVAVGKSTTARIIQTVLSRLQERLKVSLITTDGFLYPNAVLTEKQMMSRKGFPESYDVKAL
LEFLNDLKSGKEIVHAPVYSHLTYDRLEGVYETVEQADIVIIEGVNVLQTPTIEDDRTKPRVFVSDFFDFSIYVDAEEDL
IIKWYLERFRMLRETAFQDPSSYFHKFKDLADEEADHMAKSIWETVNRPNLYENILPTKFRSDLILRKGEGHKVEEILVR
RV

Sequences:

>Translated_322_residues
MRIVANQDLNLHTLYTSHTRDAWANLGGHMSVKMTEEEVKKLEGLNDYLSLEEVETVYVPLARLLYLHRATQYERNTRVN
GFLNHPHAAKIPFIIGIAGSVAVGKSTTARIIQTVLSRLQERLKVSLITTDGFLYPNAVLTEKQMMSRKGFPESYDVKAL
LEFLNDLKSGKEIVHAPVYSHLTYDRLEGVYETVEQADIVIIEGVNVLQTPTIEDDRTKPRVFVSDFFDFSIYVDAEEDL
IIKWYLERFRMLRETAFQDPSSYFHKFKDLADEEADHMAKSIWETVNRPNLYENILPTKFRSDLILRKGEGHKVEEILVR
RV
>Mature_322_residues
MRIVANQDLNLHTLYTSHTRDAWANLGGHMSVKMTEEEVKKLEGLNDYLSLEEVETVYVPLARLLYLHRATQYERNTRVN
GFLNHPHAAKIPFIIGIAGSVAVGKSTTARIIQTVLSRLQERLKVSLITTDGFLYPNAVLTEKQMMSRKGFPESYDVKAL
LEFLNDLKSGKEIVHAPVYSHLTYDRLEGVYETVEQADIVIIEGVNVLQTPTIEDDRTKPRVFVSDFFDFSIYVDAEEDL
IIKWYLERFRMLRETAFQDPSSYFHKFKDLADEEADHMAKSIWETVNRPNLYENILPTKFRSDLILRKGEGHKVEEILVR
RV

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=50.4823151125402, Blast_Score=303, Evalue=9e-84,
Organism=Drosophila melanogaster, GI45550449, Length=230, Percent_Identity=27.3913043478261, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573516, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573514, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573512, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 37225; Mature: 37225

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVANQDLNLHTLYTSHTRDAWANLGGHMSVKMTEEEVKKLEGLNDYLSLEEVETVYVP
CEEEECCCCEEEEEEECCCHHHHHHCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHH
LARLLYLHRATQYERNTRVNGFLNHPHAAKIPFIIGIAGSVAVGKSTTARIIQTVLSRLQ
HHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERLKVSLITTDGFLYPNAVLTEKQMMSRKGFPESYDVKALLEFLNDLKSGKEIVHAPVYS
HHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHEEECHHHH
HLTYDRLEGVYETVEQADIVIIEGVNVLQTPTIEDDRTKPRVFVSDFFDFSIYVDAEEDL
HHHHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCCCCCCEEEEEECCEEEEEEECCCCC
IIKWYLERFRMLRETAFQDPSSYFHKFKDLADEEADHMAKSIWETVNRPNLYENILPTKF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHH
RSDLILRKGEGHKVEEILVRRV
HCCCEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MRIVANQDLNLHTLYTSHTRDAWANLGGHMSVKMTEEEVKKLEGLNDYLSLEEVETVYVP
CEEEECCCCEEEEEEECCCHHHHHHCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHH
LARLLYLHRATQYERNTRVNGFLNHPHAAKIPFIIGIAGSVAVGKSTTARIIQTVLSRLQ
HHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERLKVSLITTDGFLYPNAVLTEKQMMSRKGFPESYDVKALLEFLNDLKSGKEIVHAPVYS
HHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHEEECHHHH
HLTYDRLEGVYETVEQADIVIIEGVNVLQTPTIEDDRTKPRVFVSDFFDFSIYVDAEEDL
HHHHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCCCCCCEEEEEECCEEEEEEECCCCC
IIKWYLERFRMLRETAFQDPSSYFHKFKDLADEEADHMAKSIWETVNRPNLYENILPTKF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHH
RSDLILRKGEGHKVEEILVRRV
HCCCEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA