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The map label for this gene is uvrX [H]

Identifier: 52786274

GI number: 52786274

Start: 2455372

End: 2456634

Strand: Reverse

Name: uvrX [H]

Synonym: BLi02536

Alternate gene names: 52786274

Gene position: 2456634-2455372 (Counterclockwise)

Preceding gene: 52786277

Following gene: 52786273

Centisome position: 58.18

GC content: 53.84

Gene sequence:

>1263_bases
ATGGATTACAGTCAATATCCGTCGCGTTCGGTTTTGTGCGTTGATATGCGGAGCTTTTATGCAAGCTGCGCCGCAGTCCT
GCTCGGACTTGACCCGATGACTTGCTTCTTGGCGGTTGTCGGAAACACGGAGCGGCAGGGAAGCATCGTTCTCGCTGCTT
CTCCGGCTCTGAAAAGAGAGTTCGGCGTTCAAACGGGAACAAGGCTTTATCAGCTGCCGGATGATCCGCGCATCAAGCTG
GTCAATCCGAAGATGGGGCTGTTTGTCCGTGTTTCTACAGAGCTCACCCGGCTGTTCTGCCGCTATGTGCCGCCTGATGC
CATTCATACGTACAGCGTGGATGAAAGCTTTATTCAGGTGGACGGTGTTGAAAGCATGTGGGGAGACGCCCGAACGATTG
CGATGAAAATTCAAGATGATATGGAAAGGGAGTTTGGCCTTCCCTGTGCTGTCGGAATCGGACCGAATCTGCTGATGGCA
AAGCTGTGCCTTGACCTTGAAGCGAAAAAATCAGCAGGCGGGGTGGCCGTTTGGGGCTACGAAGACGTGAAAACGAAGCT
GTGGCCGCTGTCTCCGCTGCGCCGCATGTGGGGAATCGGCTCCAGGCTGGAAAAGACGTTAAACCGGATGGGGATTTTTA
CAGTCGGCCAGCTGGCGCACTATGATCTCAGTCGGCTTGAGAAAACATTCGGGGTGATGGGAAACCAGCTCTATTATCAC
GCTTGGGGCATCGATCTTTCAGCGATTGGAGCGCCGCTCATGGAGGGGCAGGTCAGCTATGGAAAAAGCCAGATTCTGCT
TCGCGATTATCCGAATCCGGAGGAAGTCAAGCATGTCATTCTTGAAATGTGTGAGGAAGTGGCCAAAAGGGCGCGCGCCC
ACCGCCAGGCGGGCCGGACCGTCAGTCTCGGCATCGAATACAGCCGCGATGAGCTTGGCGGCGGATTTTACCGTTCAAAA
ACAATGGAAAGCCCTTCAAATGTCACGCTTGATCTTTACCATACATGTCTGGCACTGTTCGAGCGGTTTTATGCCGGCAA
AACGGTTCGGAAAATTTCCGTCTCTTTGTCCAATATTCAAGATGACACCAATATGCAGCTTGATCTTTTTCGCCCCGATC
AGGAAAAGAAGCGGCAGCTCGGGTATGTGATGGACGGCATCAGAGAACGGTACGGCTCAACAGCGCTTTTGCGGGCCGTT
TCCTACACAAACGCCGGGACGGCCCGTCTGCGGTCAAAATTGGTCGGAGGCCATCAGGCATAG

Upstream 100 bases:

>100_bases
ATTTTCTTTGGATAAAATTACGCCTGGAAATCGAACGTATATTCGGAGTATAGTATTCATACACTAATTGTGCGAACATC
AGTTCTTCTGGAGGGAGAGT

Downstream 100 bases:

>100_bases
AAAGGAGAATCATTTATGCTTCGCGACAGAGGCAGTATCAAATGGGTTTCCATGATGCTGCCTGAGCACGTGGAATTGCT
CAGGGAATATCATGAAAGCT

Product: UvrX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDYSQYPSRSVLCVDMRSFYASCAAVLLGLDPMTCFLAVVGNTERQGSIVLAASPALKREFGVQTGTRLYQLPDDPRIKL
VNPKMGLFVRVSTELTRLFCRYVPPDAIHTYSVDESFIQVDGVESMWGDARTIAMKIQDDMEREFGLPCAVGIGPNLLMA
KLCLDLEAKKSAGGVAVWGYEDVKTKLWPLSPLRRMWGIGSRLEKTLNRMGIFTVGQLAHYDLSRLEKTFGVMGNQLYYH
AWGIDLSAIGAPLMEGQVSYGKSQILLRDYPNPEEVKHVILEMCEEVAKRARAHRQAGRTVSLGIEYSRDELGGGFYRSK
TMESPSNVTLDLYHTCLALFERFYAGKTVRKISVSLSNIQDDTNMQLDLFRPDQEKKRQLGYVMDGIRERYGSTALLRAV
SYTNAGTARLRSKLVGGHQA

Sequences:

>Translated_420_residues
MDYSQYPSRSVLCVDMRSFYASCAAVLLGLDPMTCFLAVVGNTERQGSIVLAASPALKREFGVQTGTRLYQLPDDPRIKL
VNPKMGLFVRVSTELTRLFCRYVPPDAIHTYSVDESFIQVDGVESMWGDARTIAMKIQDDMEREFGLPCAVGIGPNLLMA
KLCLDLEAKKSAGGVAVWGYEDVKTKLWPLSPLRRMWGIGSRLEKTLNRMGIFTVGQLAHYDLSRLEKTFGVMGNQLYYH
AWGIDLSAIGAPLMEGQVSYGKSQILLRDYPNPEEVKHVILEMCEEVAKRARAHRQAGRTVSLGIEYSRDELGGGFYRSK
TMESPSNVTLDLYHTCLALFERFYAGKTVRKISVSLSNIQDDTNMQLDLFRPDQEKKRQLGYVMDGIRERYGSTALLRAV
SYTNAGTARLRSKLVGGHQA
>Mature_420_residues
MDYSQYPSRSVLCVDMRSFYASCAAVLLGLDPMTCFLAVVGNTERQGSIVLAASPALKREFGVQTGTRLYQLPDDPRIKL
VNPKMGLFVRVSTELTRLFCRYVPPDAIHTYSVDESFIQVDGVESMWGDARTIAMKIQDDMEREFGLPCAVGIGPNLLMA
KLCLDLEAKKSAGGVAVWGYEDVKTKLWPLSPLRRMWGIGSRLEKTLNRMGIFTVGQLAHYDLSRLEKTFGVMGNQLYYH
AWGIDLSAIGAPLMEGQVSYGKSQILLRDYPNPEEVKHVILEMCEEVAKRARAHRQAGRTVSLGIEYSRDELGGGFYRSK
TMESPSNVTLDLYHTCLALFERFYAGKTVRKISVSLSNIQDDTNMQLDLFRPDQEKKRQLGYVMDGIRERYGSTALLRAV
SYTNAGTARLRSKLVGGHQA

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=366, Percent_Identity=25.1366120218579, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787432, Length=405, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 47018; Mature: 47018

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYSQYPSRSVLCVDMRSFYASCAAVLLGLDPMTCFLAVVGNTERQGSIVLAASPALKRE
CCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHH
FGVQTGTRLYQLPDDPRIKLVNPKMGLFVRVSTELTRLFCRYVPPDAIHTYSVDESFIQV
HCCCCCCEEEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCEEE
DGVESMWGDARTIAMKIQDDMEREFGLPCAVGIGPNLLMAKLCLDLEAKKSAGGVAVWGY
CCCHHHCCCCEEEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEECC
EDVKTKLWPLSPLRRMWGIGSRLEKTLNRMGIFTVGQLAHYDLSRLEKTFGVMGNQLYYH
HHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AWGIDLSAIGAPLMEGQVSYGKSQILLRDYPNPEEVKHVILEMCEEVAKRARAHRQAGRT
EECCCHHHHCCHHHCCCHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VSLGIEYSRDELGGGFYRSKTMESPSNVTLDLYHTCLALFERFYAGKTVRKISVSLSNIQ
EEEEEEECHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCC
DDTNMQLDLFRPDQEKKRQLGYVMDGIRERYGSTALLRAVSYTNAGTARLRSKLVGGHQA
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MDYSQYPSRSVLCVDMRSFYASCAAVLLGLDPMTCFLAVVGNTERQGSIVLAASPALKRE
CCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHH
FGVQTGTRLYQLPDDPRIKLVNPKMGLFVRVSTELTRLFCRYVPPDAIHTYSVDESFIQV
HCCCCCCEEEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCCCEEE
DGVESMWGDARTIAMKIQDDMEREFGLPCAVGIGPNLLMAKLCLDLEAKKSAGGVAVWGY
CCCHHHCCCCEEEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEECC
EDVKTKLWPLSPLRRMWGIGSRLEKTLNRMGIFTVGQLAHYDLSRLEKTFGVMGNQLYYH
HHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AWGIDLSAIGAPLMEGQVSYGKSQILLRDYPNPEEVKHVILEMCEEVAKRARAHRQAGRT
EECCCHHHHCCHHHCCCHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VSLGIEYSRDELGGGFYRSKTMESPSNVTLDLYHTCLALFERFYAGKTVRKISVSLSNIQ
EEEEEEECHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCC
DDTNMQLDLFRPDQEKKRQLGYVMDGIRERYGSTALLRAVSYTNAGTARLRSKLVGGHQA
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]