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The map label for this gene is dinF [H]

Identifier: 52786270

GI number: 52786270

Start: 2452785

End: 2454143

Strand: Direct

Name: dinF [H]

Synonym: BLi02532

Alternate gene names: 52786270

Gene position: 2452785-2454143 (Clockwise)

Preceding gene: 52786269

Following gene: 52786275

Centisome position: 58.09

GC content: 49.82

Gene sequence:

>1359_bases
ATGAATCACAAGCAATATCTAGCACTCGCCGTTCCGCTGATCATTTCAACGATCACCACTCCTTTATTGGGTGCGGTCGA
TACGGCGGTCGCCGGCCAGCTTTCCTCCCCTGCTTACATCGGCGGTGTTGCAGTCGGAACGATGATTTTTAATACGATGT
ATTGGCTCCTCGGTTTTTTGCGGGTAAGCACATCCGGATTCGCCGCTCAGTCACTCGGCTCCCAAAACAGATCAGAGAGC
GTTTTGGCCCTTGCCCGGCCCGTTTTCATCGCGCTGTTTGCCGGACTGATGTTCATCATCTTGCAAAAACCGCTTGAATA
CGCAGCGCTGACGCTCATACAGCCCGACCGCCATACCGCTGAATTCGCCTCGCAGTATTTTTCGCTGAGGATTTGGGGAG
CTCCATTTGCTTTAATCAGCTATTGCATTCTCGGCTGGCTGATGGGAATGTCTCTAATCAAAGTGACATTGCTTTTGCAG
ATTTCGATGAACGTCTTGAATATCGTGCTTGACATCGTTTTTGTCTACGTCTTTCACATGGAAGTATACGGCATCGCTCT
AGCCACTTTGATTTCGGATGTGACGGGCTGCCTGATCGGCTGCTGGCTTGTGAAAACGAATGCCGCCATGCCGTTTAAGC
TGCCGTCCGTCAAGCTTTTATTCGACCCGAAACCGTTTAAAAAAATGATGGTTGTCAACCGAGATCTATTGATTCGGACA
TTGTGCCTTTTGACGGTTTTCAATTTATTTACGGCTAAAGGAGCCGGCTTCGGCGCTGAAATTTTAGCCGCAAATGCGAT
CTTGATTCAAATTCATTATTTGATGGCTTATGTTTTTGACGGGTTTGCCAATGCATCGAGCATCTTTGCCGGGAAAGCCG
TTGGAAGAATGGATCGGGATCTCTATTCCCGTACGCTTTCCCTTTCGATCCAGTGGTCGCTGATCTCGGCCGCGCTGCTT
TCAGTCGGCTACTTTCTCTTGAGAAATGCGATCCTTCCATTGTTTACACCGCTTGAAAGCGTTCTGGAAGCAGCGAAAAC
TTACGATGTTTGGATCGCTCTCTTTCCTTTGGCCGCAAGTTTCGGACTCGTTTTTTACGGGATTTTCACAGGCGCCACCG
AAATAGGCCCGGTCAGAAATTCAATGTTTTTGGCTGTTCTCGTCTTCCTGGCCGCCTTTTTTACCGCTGTCCCCGCTTTC
GGAAACCATGGGCTGTGGCTCGCTTTTCTTTTATTCAGCCTTGGGCGTTCCGTATTCTTATGCATGGCTGTTCCCGGGCT
GACCACCCGGCTTTTCGGAGAGCGCAGTGCTGCGAGAGAGGCAGGCCAAAGACCGAAATCATTAAAACACCCCGGCTAA

Upstream 100 bases:

>100_bases
TGCCGATCAATTTGAAAAAGAAGAGCTTTTTTCTGCCGAAAGGCACCCATATGCCAAAAAGCTGCTTCAGGTGTTTGAAT
CCTAAGGGGGGTCTTAACAG

Downstream 100 bases:

>100_bases
GCTTTAGCCGGGGTGTTTACGTTTATTCTTTCGTTAATTGTGCGACGAAATGGTTCAGATGATCCAGCGTCATCAAATTT
TGATTGCATTTTTCACTGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNHKQYLALAVPLIISTITTPLLGAVDTAVAGQLSSPAYIGGVAVGTMIFNTMYWLLGFLRVSTSGFAAQSLGSQNRSES
VLALARPVFIALFAGLMFIILQKPLEYAALTLIQPDRHTAEFASQYFSLRIWGAPFALISYCILGWLMGMSLIKVTLLLQ
ISMNVLNIVLDIVFVYVFHMEVYGIALATLISDVTGCLIGCWLVKTNAAMPFKLPSVKLLFDPKPFKKMMVVNRDLLIRT
LCLLTVFNLFTAKGAGFGAEILAANAILIQIHYLMAYVFDGFANASSIFAGKAVGRMDRDLYSRTLSLSIQWSLISAALL
SVGYFLLRNAILPLFTPLESVLEAAKTYDVWIALFPLAASFGLVFYGIFTGATEIGPVRNSMFLAVLVFLAAFFTAVPAF
GNHGLWLAFLLFSLGRSVFLCMAVPGLTTRLFGERSAAREAGQRPKSLKHPG

Sequences:

>Translated_452_residues
MNHKQYLALAVPLIISTITTPLLGAVDTAVAGQLSSPAYIGGVAVGTMIFNTMYWLLGFLRVSTSGFAAQSLGSQNRSES
VLALARPVFIALFAGLMFIILQKPLEYAALTLIQPDRHTAEFASQYFSLRIWGAPFALISYCILGWLMGMSLIKVTLLLQ
ISMNVLNIVLDIVFVYVFHMEVYGIALATLISDVTGCLIGCWLVKTNAAMPFKLPSVKLLFDPKPFKKMMVVNRDLLIRT
LCLLTVFNLFTAKGAGFGAEILAANAILIQIHYLMAYVFDGFANASSIFAGKAVGRMDRDLYSRTLSLSIQWSLISAALL
SVGYFLLRNAILPLFTPLESVLEAAKTYDVWIALFPLAASFGLVFYGIFTGATEIGPVRNSMFLAVLVFLAAFFTAVPAF
GNHGLWLAFLLFSLGRSVFLCMAVPGLTTRLFGERSAAREAGQRPKSLKHPG
>Mature_452_residues
MNHKQYLALAVPLIISTITTPLLGAVDTAVAGQLSSPAYIGGVAVGTMIFNTMYWLLGFLRVSTSGFAAQSLGSQNRSES
VLALARPVFIALFAGLMFIILQKPLEYAALTLIQPDRHTAEFASQYFSLRIWGAPFALISYCILGWLMGMSLIKVTLLLQ
ISMNVLNIVLDIVFVYVFHMEVYGIALATLISDVTGCLIGCWLVKTNAAMPFKLPSVKLLFDPKPFKKMMVVNRDLLIRT
LCLLTVFNLFTAKGAGFGAEILAANAILIQIHYLMAYVFDGFANASSIFAGKAVGRMDRDLYSRTLSLSIQWSLISAALL
SVGYFLLRNAILPLFTPLESVLEAAKTYDVWIALFPLAASFGLVFYGIFTGATEIGPVRNSMFLAVLVFLAAFFTAVPAF
GNHGLWLAFLLFSLGRSVFLCMAVPGLTTRLFGERSAAREAGQRPKSLKHPG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=413, Percent_Identity=36.319612590799, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49283; Mature: 49283

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHKQYLALAVPLIISTITTPLLGAVDTAVAGQLSSPAYIGGVAVGTMIFNTMYWLLGFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVSTSGFAAQSLGSQNRSESVLALARPVFIALFAGLMFIILQKPLEYAALTLIQPDRHTA
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCHHH
EFASQYFSLRIWGAPFALISYCILGWLMGMSLIKVTLLLQISMNVLNIVLDIVFVYVFHM
HHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYGIALATLISDVTGCLIGCWLVKTNAAMPFKLPSVKLLFDPKPFKKMMVVNRDLLIRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHH
LCLLTVFNLFTAKGAGFGAEILAANAILIQIHYLMAYVFDGFANASSIFAGKAVGRMDRD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYSRTLSLSIQWSLISAALLSVGYFLLRNAILPLFTPLESVLEAAKTYDVWIALFPLAAS
HHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLVFYGIFTGATEIGPVRNSMFLAVLVFLAAFFTAVPAFGNHGLWLAFLLFSLGRSVFL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
CMAVPGLTTRLFGERSAAREAGQRPKSLKHPG
HHHCCCHHHHHHCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNHKQYLALAVPLIISTITTPLLGAVDTAVAGQLSSPAYIGGVAVGTMIFNTMYWLLGFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RVSTSGFAAQSLGSQNRSESVLALARPVFIALFAGLMFIILQKPLEYAALTLIQPDRHTA
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCHHH
EFASQYFSLRIWGAPFALISYCILGWLMGMSLIKVTLLLQISMNVLNIVLDIVFVYVFHM
HHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYGIALATLISDVTGCLIGCWLVKTNAAMPFKLPSVKLLFDPKPFKKMMVVNRDLLIRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHH
LCLLTVFNLFTAKGAGFGAEILAANAILIQIHYLMAYVFDGFANASSIFAGKAVGRMDRD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYSRTLSLSIQWSLISAALLSVGYFLLRNAILPLFTPLESVLEAAKTYDVWIALFPLAAS
HHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLVFYGIFTGATEIGPVRNSMFLAVLVFLAAFFTAVPAFGNHGLWLAFLLFSLGRSVFL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
CMAVPGLTTRLFGERSAAREAGQRPKSLKHPG
HHHCCCHHHHHHCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]