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The map label for this gene is yqkF [H]

Identifier: 52786255

GI number: 52786255

Start: 2441505

End: 2442425

Strand: Direct

Name: yqkF [H]

Synonym: BLi02516

Alternate gene names: 52786255

Gene position: 2441505-2442425 (Clockwise)

Preceding gene: 52786254

Following gene: 52786256

Centisome position: 57.82

GC content: 49.29

Gene sequence:

>921_bases
ATGAAAAAAAGGACGCTCGGACATTCCGATTTACAGGTGAGTGAAGTCGGCCTAGGCTGCATGTCTCTCGGAACGGACAA
AAAGCACGCACTGTCAATTCTGGATGAAGCTTTGGAACTCGGCATCAATTACTTGGATACTGCCGACCTGTACGATTTTG
GACGCAACGAAGAAATTGTCGGTGAAGCGATCAAATCAAGGCGCCAAGATGTCATCCTCGCCACAAAAGCGGGAAACCGC
TGGGAGGAAGGAAAACCGGGCTGGTTCTGGGATCCCCGGAAAGCATACATAAAAGAAGCCGTCAAACGCAGCTTAAAGCG
GCTGCAAACCGACTATATCGATCTTTATCAGCTGCATGGCGGAACGATCGAAGATAACATCGACGAAACGATTGAGGCCT
TTGAAGAGTTAAAACAGGAAGGCGTCATCCGCCATTACGGCATTTCCTCGATCCGGCCGAACGTCATAAAGGAATACGTC
AAAAAATCAAACATCGTCACAGTCATGATGCAATACAGCTTGTTGGACAGACGGCCTGAGGAATGGCTTTCTCTCCTTGA
AGAACATGGAATCAGCGTGATTGCAAGAGGACCTCTGGCAAAAGGGATTCTGACAGAAAAACCCCTGTCAGATGCAAACG
CATCGATTAAGAAAAGCGGCTATTTATCATATTCCTACGATGAACTCATCAAAACAAAGGCGGACATTGAAAAAACAGCG
CCTGATTTATCCGCAACCGAAACCGCGCTGAAGTATATTCTCGCCCAGCCGGCTGTCGGCGCGGTCATCCCCGGGGCGAG
CAAACTCTCCCAGCTTCGGGAAAACGTTGAATCTGTCGGCGGACGCAGCCTGACAGAACAGGAAATCAAAGCGCTCCGCT
TTTATACAAAACGCGACGTGTACACTGCGCATCGCGAATGA

Upstream 100 bases:

>100_bases
ATGATCATCGTCGAGCTGTACTTCTGATCCCGATGCCGATGGGTTGAAAACTTCGCTCCTTTGTATTACGGTCAAAGTAA
GAAAAAAAGGAGTGAGGCTT

Downstream 100 bases:

>100_bases
ATTCAATAAGAAAGCACCGTCTCTTTGGCAGACGGTGCTTCTTTACTTATACTTCCTCCAGTCGTCAAGTCCGCTTTCGT
TGAGGAGTTCTTCAAAGCTT

Product: YqkF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKKRTLGHSDLQVSEVGLGCMSLGTDKKHALSILDEALELGINYLDTADLYDFGRNEEIVGEAIKSRRQDVILATKAGNR
WEEGKPGWFWDPRKAYIKEAVKRSLKRLQTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRHYGISSIRPNVIKEYV
KKSNIVTVMMQYSLLDRRPEEWLSLLEEHGISVIARGPLAKGILTEKPLSDANASIKKSGYLSYSYDELIKTKADIEKTA
PDLSATETALKYILAQPAVGAVIPGASKLSQLRENVESVGGRSLTEQEIKALRFYTKRDVYTAHRE

Sequences:

>Translated_306_residues
MKKRTLGHSDLQVSEVGLGCMSLGTDKKHALSILDEALELGINYLDTADLYDFGRNEEIVGEAIKSRRQDVILATKAGNR
WEEGKPGWFWDPRKAYIKEAVKRSLKRLQTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRHYGISSIRPNVIKEYV
KKSNIVTVMMQYSLLDRRPEEWLSLLEEHGISVIARGPLAKGILTEKPLSDANASIKKSGYLSYSYDELIKTKADIEKTA
PDLSATETALKYILAQPAVGAVIPGASKLSQLRENVESVGGRSLTEQEIKALRFYTKRDVYTAHRE
>Mature_306_residues
MKKRTLGHSDLQVSEVGLGCMSLGTDKKHALSILDEALELGINYLDTADLYDFGRNEEIVGEAIKSRRQDVILATKAGNR
WEEGKPGWFWDPRKAYIKEAVKRSLKRLQTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRHYGISSIRPNVIKEYV
KKSNIVTVMMQYSLLDRRPEEWLSLLEEHGISVIARGPLAKGILTEKPLSDANASIKKSGYLSYSYDELIKTKADIEKTA
PDLSATETALKYILAQPAVGAVIPGASKLSQLRENVESVGGRSLTEQEIKALRFYTKRDVYTAHRE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=26.2345679012346, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=26.1682242990654, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=27.4760383386581, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718702, Length=298, Percent_Identity=29.8657718120805, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=26.7741935483871, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI310109922, Length=279, Percent_Identity=27.2401433691756, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=26.8456375838926, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=26.8456375838926, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=27.1812080536913, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI41327764, Length=296, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=32.2475570032573, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081735, Length=304, Percent_Identity=32.8947368421053, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789199, Length=323, Percent_Identity=30.6501547987616, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787674, Length=280, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=27.1028037383178, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788081, Length=285, Percent_Identity=27.719298245614, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082198, Length=212, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786400, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=139, Percent_Identity=32.3741007194245, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=306, Percent_Identity=28.4313725490196, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=26.7267267267267, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=25.752508361204, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=25.3869969040248, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321052, Length=147, Percent_Identity=29.9319727891156, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646155, Length=324, Percent_Identity=30.2469135802469, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24646159, Length=220, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45553081, Length=318, Percent_Identity=26.1006289308176, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281366140, Length=294, Percent_Identity=25.5102040816327, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646157, Length=212, Percent_Identity=26.8867924528302, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34447; Mature: 34447

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRTLGHSDLQVSEVGLGCMSLGTDKKHALSILDEALELGINYLDTADLYDFGRNEEIV
CCCCCCCCCCCCHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
GEAIKSRRQDVILATKAGNRWEEGKPGWFWDPRKAYIKEAVKRSLKRLQTDYIDLYQLHG
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDNIDETIEAFEELKQEGVIRHYGISSIRPNVIKEYVKKSNIVTVMMQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHH
EWLSLLEEHGISVIARGPLAKGILTEKPLSDANASIKKSGYLSYSYDELIKTKADIEKTA
HHHHHHHHCCCEEEECCCCHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCC
PDLSATETALKYILAQPAVGAVIPGASKLSQLRENVESVGGRSLTEQEIKALRFYTKRDV
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
YTAHRE
HHCCCC
>Mature Secondary Structure
MKKRTLGHSDLQVSEVGLGCMSLGTDKKHALSILDEALELGINYLDTADLYDFGRNEEIV
CCCCCCCCCCCCHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHH
GEAIKSRRQDVILATKAGNRWEEGKPGWFWDPRKAYIKEAVKRSLKRLQTDYIDLYQLHG
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDNIDETIEAFEELKQEGVIRHYGISSIRPNVIKEYVKKSNIVTVMMQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHH
EWLSLLEEHGISVIARGPLAKGILTEKPLSDANASIKKSGYLSYSYDELIKTKADIEKTA
HHHHHHHHCCCEEEECCCCHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCC
PDLSATETALKYILAQPAVGAVIPGASKLSQLRENVESVGGRSLTEQEIKALRFYTKRDV
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
YTAHRE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]