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The map label for this gene is ywoE [H]

Identifier: 52786246

GI number: 52786246

Start: 2435454

End: 2436377

Strand: Direct

Name: ywoE [H]

Synonym: BLi02507

Alternate gene names: 52786246

Gene position: 2435454-2436377 (Clockwise)

Preceding gene: 52786226

Following gene: 52786247

Centisome position: 57.68

GC content: 51.3

Gene sequence:

>924_bases
ATGAAACCTGTCCATCAAGAAAAAATTCAAACAGACCTCACGCTCTCAAACAGCGACTTGCAGCCTCTGAAGCCGGAGGA
ACGCACATGGAAAGCGGTTAATTTCGCATCGATCTGGATGGGCTGCATCCATAACATCCCGACTTATGCAACGGTTGGCG
GACTGATTGCGATCGGACTTTCTCCGTGGCAAGTGCTTGGGATTATCGCCGTCGCTTCGATTGTTCTCTACGCGGCCCTC
GCGTTGAATGGACATGCCGGCGCAAAATACGGCGTGCCTTTTCCAGTATTAATTAGGTCTTCTTTCGGGATCTACGGGGC
TAATATACCGGCGCTCCTCAGAGGTTTCGTAGCGATTATGTGGTTCGGCATTCAAGCGTTTGCGGGAAGCACGGCGATCA
ACATCCTGATCTTAAACGTATGGAGCGGCTGGAAAGACATCGGCGGCGACTGGAACTTATTTGGTTTGCATTTACCGGGT
CTTTTGTCATTTGTTTTCTTTTGGGGGATTCATCTTCTCGTCCTCCATCACGGAATGGAGTCGATTAGAAGGTTTGAAGT
CTGGGCCGGCCCGCTCGTTTATCTCGTCTTTGGCGGGATGGTGTGGTGGGCGGTCGATATTGCAGGGGGGCTCGGTCCGA
TTTATTCGCAGCCGGGAAAATTTCAGACATTCAGCGAATTAATTTGGCCATTTCTTGCCGGTGTGACGGGGATTATCGGC
ATTTGGGCGACGCTCATTTTGAACATTCCCGATTTTACGAGGTTTGCAGCCTCCCAAAAAGAACAAATCAGAGGACAGTT
TTACGGTTTGCCGGGCACATTCGTTCTGCAAGCATCACCGTCACCTCCGGCTCACAGGCTGCCTTCGGGGAGCCGATTTG
GGACGTGGTCGATATTCTCGCCCATTTTGACAATCCGTACGTGA

Upstream 100 bases:

>100_bases
GTCAACCTCAACAAACGCCTTGAAACATTTGTTTAGTTTATCTAATGAATTTTTCAGGATAATGAGTTATATTTTTCCTT
AAAAAATCCGGAGGGATTAC

Downstream 100 bases:

>100_bases
TCGCTCTTTCGGTCATTACGCTTTGCATCGCCGCCATTTCGGTAAACGTTGCGGCAAATATTGTCTCGCCTGCCTATGAT
CTGGCCAATTTTTTGCCGAA

Product: YwoE

Products: NA

Alternate protein names: Allantoin transport protein [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKPVHQEKIQTDLTLSNSDLQPLKPEERTWKAVNFASIWMGCIHNIPTYATVGGLIAIGLSPWQVLGIIAVASIVLYAAL
ALNGHAGAKYGVPFPVLIRSSFGIYGANIPALLRGFVAIMWFGIQAFAGSTAINILILNVWSGWKDIGGDWNLFGLHLPG
LLSFVFFWGIHLLVLHHGMESIRRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFQTFSELIWPFLAGVTGIIG
IWATLILNIPDFTRFAASQKEQIRGQFYGLPGTFVLQASPSPPAHRLPSGSRFGTWSIFSPILTIRT

Sequences:

>Translated_307_residues
MKPVHQEKIQTDLTLSNSDLQPLKPEERTWKAVNFASIWMGCIHNIPTYATVGGLIAIGLSPWQVLGIIAVASIVLYAAL
ALNGHAGAKYGVPFPVLIRSSFGIYGANIPALLRGFVAIMWFGIQAFAGSTAINILILNVWSGWKDIGGDWNLFGLHLPG
LLSFVFFWGIHLLVLHHGMESIRRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFQTFSELIWPFLAGVTGIIG
IWATLILNIPDFTRFAASQKEQIRGQFYGLPGTFVLQASPSPPAHRLPSGSRFGTWSIFSPILTIRT
>Mature_307_residues
MKPVHQEKIQTDLTLSNSDLQPLKPEERTWKAVNFASIWMGCIHNIPTYATVGGLIAIGLSPWQVLGIIAVASIVLYAAL
ALNGHAGAKYGVPFPVLIRSSFGIYGANIPALLRGFVAIMWFGIQAFAGSTAINILILNVWSGWKDIGGDWNLFGLHLPG
LLSFVFFWGIHLLVLHHGMESIRRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFQTFSELIWPFLAGVTGIIG
IWATLILNIPDFTRFAASQKEQIRGQFYGLPGTFVLQASPSPPAHRLPSGSRFGTWSIFSPILTIRT

Specific function: Transport of allantoin [H]

COG id: COG1953

COG function: function code FH; Cytosine/uracil/thiamine/allantoin permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI87081749, Length=276, Percent_Identity=40.2173913043478, Blast_Score=194, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6322219, Length=276, Percent_Identity=28.6231884057971, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319495, Length=274, Percent_Identity=26.6423357664234, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319429, Length=279, Percent_Identity=26.1648745519713, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324766, Length=257, Percent_Identity=22.568093385214, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323266, Length=257, Percent_Identity=22.568093385214, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 33629; Mature: 33629

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVHQEKIQTDLTLSNSDLQPLKPEERTWKAVNFASIWMGCIHNIPTYATVGGLIAIGL
CCCCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SPWQVLGIIAVASIVLYAALALNGHAGAKYGVPFPVLIRSSFGIYGANIPALLRGFVAIM
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
WFGIQAFAGSTAINILILNVWSGWKDIGGDWNLFGLHLPGLLSFVFFWGIHLLVLHHGME
HHHHHHHCCCCEEEEEEEEECCCHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
SIRRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFQTFSELIWPFLAGVTGIIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHH
IWATLILNIPDFTRFAASQKEQIRGQFYGLPGTFVLQASPSPPAHRLPSGSRFGTWSIFS
HHHHHHHCCCCHHHHHHHHHHHHCHHEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
PILTIRT
HHHHCCC
>Mature Secondary Structure
MKPVHQEKIQTDLTLSNSDLQPLKPEERTWKAVNFASIWMGCIHNIPTYATVGGLIAIGL
CCCCCHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SPWQVLGIIAVASIVLYAALALNGHAGAKYGVPFPVLIRSSFGIYGANIPALLRGFVAIM
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
WFGIQAFAGSTAINILILNVWSGWKDIGGDWNLFGLHLPGLLSFVFFWGIHLLVLHHGME
HHHHHHHCCCCEEEEEEEEECCCHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
SIRRFEVWAGPLVYLVFGGMVWWAVDIAGGLGPIYSQPGKFQTFSELIWPFLAGVTGIIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHH
IWATLILNIPDFTRFAASQKEQIRGQFYGLPGTFVLQASPSPPAHRLPSGSRFGTWSIFS
HHHHHHHCCCCHHHHHHHHHHHHCHHEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
PILTIRT
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 11344136 [H]