| Definition | Bacillus licheniformis ATCC 14580, complete genome. |
|---|---|
| Accession | NC_006322 |
| Length | 4,222,645 |
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The map label for this gene is ppiB [H]
Identifier: 52786220
GI number: 52786220
Start: 2414542
End: 2414979
Strand: Reverse
Name: ppiB [H]
Synonym: BLi02481
Alternate gene names: 52786220
Gene position: 2414979-2414542 (Counterclockwise)
Preceding gene: 52786224
Following gene: 52786219
Centisome position: 57.19
GC content: 51.37
Gene sequence:
>438_bases ATGGCTAAAAAAGGATACATACAACTGACAAACGGCAAAAAAATCGAGTTTGAACTATATCCGGATGCGGCGCCGGGAAC TGTCGCCAACTTTGAAAAACTTGCAAACGAAGGGTTCTATGACGGGCTGAAGTTCCACCGCGTCATCCCGGGCTTCGTCA GCCAGGGAGGCTGCCCGCACGGCACCGGAACAGGCGGACCTGGATATACGATTAAATGCGAGACAGAAGGGAATCCGCAC AAACACGAAGCCGGTTCTCTCTCAATGGCTCACGCAGGAAAAGATACCGGAGGCAGCCAATTCTTTATCGTCCATGAGCC TCAGCCGCACTTGAACGGCGTTCACACCGTTTTCGGAAAGGTCACATCAGGCCTTGATGCCGTCACTTCAATGGAGCAGG GACAAGGCATGGAAAAAGTCGAAGTATTTGATGCATAA
Upstream 100 bases:
>100_bases TACAAAAACGATACAAGAGCGGCGTTTATTTCGGTCGATTGGCTCTCTGCTTCTTCAATATGATATAATGACCCTTGTGA AATGAAAGGAGAGAATCAAG
Downstream 100 bases:
>100_bases TCAGAGAGCGCAAAAAACAGCCCGCTTAGCCGGGCTGTTTTTTTGTCTGTAACGGTGTTTATTTTCCAGGTGCAACAGGA CTTGAGGCCGATTCTTCGTC
Product: PpiB
Products: NA
Alternate protein names: PPIase B; Rotamase B [H]
Number of amino acids: Translated: 145; Mature: 144
Protein sequence:
>145_residues MAKKGYIQLTNGKKIEFELYPDAAPGTVANFEKLANEGFYDGLKFHRVIPGFVSQGGCPHGTGTGGPGYTIKCETEGNPH KHEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLDAVTSMEQGQGMEKVEVFDA
Sequences:
>Translated_145_residues MAKKGYIQLTNGKKIEFELYPDAAPGTVANFEKLANEGFYDGLKFHRVIPGFVSQGGCPHGTGTGGPGYTIKCETEGNPH KHEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLDAVTSMEQGQGMEKVEVFDA >Mature_144_residues AKKGYIQLTNGKKIEFELYPDAAPGTVANFEKLANEGFYDGLKFHRVIPGFVSQGGCPHGTGTGGPGYTIKCETEGNPHK HEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLDAVTSMEQGQGMEKVEVFDA
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=140, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=3e-22, Organism=Homo sapiens, GI24308049, Length=120, Percent_Identity=42.5, Blast_Score=92, Evalue=1e-19, Organism=Homo sapiens, GI10863927, Length=143, Percent_Identity=43.3566433566434, Blast_Score=92, Evalue=1e-19, Organism=Homo sapiens, GI19557636, Length=128, Percent_Identity=42.96875, Blast_Score=91, Evalue=3e-19, Organism=Homo sapiens, GI64276486, Length=125, Percent_Identity=42.4, Blast_Score=91, Evalue=4e-19, Organism=Homo sapiens, GI310127646, Length=143, Percent_Identity=41.958041958042, Blast_Score=91, Evalue=5e-19, Organism=Homo sapiens, GI310114371, Length=143, Percent_Identity=41.958041958042, Blast_Score=91, Evalue=5e-19, Organism=Homo sapiens, GI310119221, Length=143, Percent_Identity=41.958041958042, Blast_Score=91, Evalue=5e-19, Organism=Homo sapiens, GI22547212, Length=151, Percent_Identity=41.0596026490066, Blast_Score=87, Evalue=6e-18, Organism=Homo sapiens, GI7657473, Length=151, Percent_Identity=41.0596026490066, Blast_Score=87, Evalue=6e-18, Organism=Homo sapiens, GI22547215, Length=151, Percent_Identity=41.0596026490066, Blast_Score=86, Evalue=9e-18, Organism=Homo sapiens, GI4826932, Length=133, Percent_Identity=41.3533834586466, Blast_Score=85, Evalue=3e-17, Organism=Homo sapiens, GI4758950, Length=126, Percent_Identity=45.2380952380952, Blast_Score=83, Evalue=7e-17, Organism=Homo sapiens, GI6631100, Length=133, Percent_Identity=42.1052631578947, Blast_Score=83, Evalue=8e-17, Organism=Homo sapiens, GI256017253, Length=126, Percent_Identity=42.8571428571429, Blast_Score=82, Evalue=1e-16, Organism=Homo sapiens, GI221139811, Length=126, Percent_Identity=42.8571428571429, Blast_Score=82, Evalue=1e-16, Organism=Homo sapiens, GI256017251, Length=126, Percent_Identity=42.8571428571429, Blast_Score=82, Evalue=1e-16, Organism=Homo sapiens, GI178057341, Length=125, Percent_Identity=43.2, Blast_Score=82, Evalue=2e-16, Organism=Homo sapiens, GI45439316, Length=128, Percent_Identity=41.40625, Blast_Score=81, Evalue=3e-16, Organism=Homo sapiens, GI5174637, Length=143, Percent_Identity=39.8601398601399, Blast_Score=81, Evalue=3e-16, Organism=Homo sapiens, GI303305009, Length=125, Percent_Identity=42.4, Blast_Score=81, Evalue=4e-16, Organism=Homo sapiens, GI310129267, Length=125, Percent_Identity=42.4, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI310120620, Length=125, Percent_Identity=42.4, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI42560244, Length=133, Percent_Identity=42.1052631578947, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI5031987, Length=149, Percent_Identity=40.2684563758389, Blast_Score=80, Evalue=8e-16, Organism=Homo sapiens, GI209417936, Length=125, Percent_Identity=42.4, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI30102944, Length=125, Percent_Identity=42.4, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI219842199, Length=125, Percent_Identity=42.4, Blast_Score=79, Evalue=1e-15, Organism=Homo sapiens, GI169164185, Length=142, Percent_Identity=39.4366197183099, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI169163623, Length=142, Percent_Identity=39.4366197183099, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI4505991, Length=127, Percent_Identity=46.4566929133858, Blast_Score=78, Evalue=3e-15, Organism=Homo sapiens, GI169163387, Length=142, Percent_Identity=39.4366197183099, Blast_Score=77, Evalue=4e-15, Organism=Homo sapiens, GI310110104, Length=142, Percent_Identity=38.7323943661972, Blast_Score=77, Evalue=4e-15, Organism=Homo sapiens, GI150418007, Length=125, Percent_Identity=42.4, Blast_Score=76, Evalue=1e-14, Organism=Homo sapiens, GI310132444, Length=142, Percent_Identity=38.0281690140845, Blast_Score=74, Evalue=4e-14, Organism=Homo sapiens, GI310113152, Length=142, Percent_Identity=38.0281690140845, Blast_Score=74, Evalue=4e-14, Organism=Homo sapiens, GI310127745, Length=125, Percent_Identity=40.8, Blast_Score=71, Evalue=4e-13, Organism=Homo sapiens, GI310119290, Length=125, Percent_Identity=40.8, Blast_Score=71, Evalue=4e-13, Organism=Homo sapiens, GI310114540, Length=125, Percent_Identity=40.8, Blast_Score=70, Evalue=5e-13, Organism=Homo sapiens, GI169214050, Length=124, Percent_Identity=40.3225806451613, Blast_Score=70, Evalue=5e-13, Organism=Homo sapiens, GI239751853, Length=124, Percent_Identity=40.3225806451613, Blast_Score=70, Evalue=6e-13, Organism=Homo sapiens, GI113428306, Length=124, Percent_Identity=40.3225806451613, Blast_Score=70, Evalue=6e-13, Organism=Homo sapiens, GI5454154, Length=131, Percent_Identity=37.4045801526718, Blast_Score=70, Evalue=6e-13, Organism=Homo sapiens, GI20911035, Length=127, Percent_Identity=37.007874015748, Blast_Score=70, Evalue=7e-13, Organism=Escherichia coli, GI1789763, Length=144, Percent_Identity=38.1944444444444, Blast_Score=74, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17539496, Length=121, Percent_Identity=48.7603305785124, Blast_Score=106, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17532641, Length=146, Percent_Identity=36.986301369863, Blast_Score=91, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17506307, Length=131, Percent_Identity=46.5648854961832, Blast_Score=89, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17506311, Length=129, Percent_Identity=41.8604651162791, Blast_Score=87, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17552780, Length=126, Percent_Identity=46.8253968253968, Blast_Score=87, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17539498, Length=126, Percent_Identity=43.6507936507937, Blast_Score=85, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551282, Length=132, Percent_Identity=43.1818181818182, Blast_Score=85, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551284, Length=132, Percent_Identity=43.1818181818182, Blast_Score=85, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17559074, Length=133, Percent_Identity=42.8571428571429, Blast_Score=85, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71997782, Length=118, Percent_Identity=42.3728813559322, Blast_Score=84, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17566266, Length=132, Percent_Identity=43.1818181818182, Blast_Score=82, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17552782, Length=135, Percent_Identity=40.7407407407407, Blast_Score=82, Evalue=8e-17, Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=37.8787878787879, Blast_Score=82, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17565860, Length=133, Percent_Identity=41.3533834586466, Blast_Score=82, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=37.8787878787879, Blast_Score=82, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17532643, Length=131, Percent_Identity=38.9312977099237, Blast_Score=70, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17552784, Length=134, Percent_Identity=34.3283582089552, Blast_Score=64, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323562, Length=126, Percent_Identity=48.4126984126984, Blast_Score=98, Evalue=5e-22, Organism=Saccharomyces cerevisiae, GI6320359, Length=126, Percent_Identity=46.8253968253968, Blast_Score=88, Evalue=5e-19, Organism=Saccharomyces cerevisiae, GI6323246, Length=137, Percent_Identity=43.7956204379562, Blast_Score=84, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6320510, Length=146, Percent_Identity=41.0958904109589, Blast_Score=83, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6321848, Length=128, Percent_Identity=44.53125, Blast_Score=81, Evalue=8e-17, Organism=Drosophila melanogaster, GI19922376, Length=146, Percent_Identity=42.4657534246575, Blast_Score=105, Evalue=9e-24, Organism=Drosophila melanogaster, GI17986117, Length=121, Percent_Identity=44.6280991735537, Blast_Score=101, Evalue=2e-22, Organism=Drosophila melanogaster, GI20130249, Length=127, Percent_Identity=48.0314960629921, Blast_Score=95, Evalue=2e-20, Organism=Drosophila melanogaster, GI24650807, Length=133, Percent_Identity=43.609022556391, Blast_Score=92, Evalue=1e-19, Organism=Drosophila melanogaster, GI21357249, Length=120, Percent_Identity=40, Blast_Score=89, Evalue=9e-19, Organism=Drosophila melanogaster, GI45549139, Length=125, Percent_Identity=45.6, Blast_Score=85, Evalue=2e-17, Organism=Drosophila melanogaster, GI24664125, Length=125, Percent_Identity=45.6, Blast_Score=83, Evalue=6e-17, Organism=Drosophila melanogaster, GI21357783, Length=125, Percent_Identity=45.6, Blast_Score=83, Evalue=6e-17, Organism=Drosophila melanogaster, GI17647301, Length=126, Percent_Identity=42.8571428571429, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI24652460, Length=122, Percent_Identity=36.0655737704918, Blast_Score=80, Evalue=4e-16, Organism=Drosophila melanogaster, GI17136360, Length=150, Percent_Identity=35.3333333333333, Blast_Score=75, Evalue=2e-14, Organism=Drosophila melanogaster, GI19922912, Length=135, Percent_Identity=40.7407407407407, Blast_Score=72, Evalue=1e-13, Organism=Drosophila melanogaster, GI24586038, Length=133, Percent_Identity=38.3458646616541, Blast_Score=72, Evalue=2e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 15407; Mature: 15276
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKKGYIQLTNGKKIEFELYPDAAPGTVANFEKLANEGFYDGLKFHRVIPGFVSQGGCPH CCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEHHHCCCHHHHCCCCCC GTGTGGPGYTIKCETEGNPHKHEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGK CCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHH VTSGLDAVTSMEQGQGMEKVEVFDA HHCCHHHHHHHHHCCCCCEEEEECC >Mature Secondary Structure AKKGYIQLTNGKKIEFELYPDAAPGTVANFEKLANEGFYDGLKFHRVIPGFVSQGGCPH CCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEHHHCCCHHHHCCCCCC GTGTGGPGYTIKCETEGNPHKHEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGK CCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHH VTSGLDAVTSMEQGQGMEKVEVFDA HHCCHHHHHHHHHCCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934829; 8022278; 9384377; 8755892 [H]