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The map label for this gene is resD [H]

Identifier: 52786197

GI number: 52786197

Start: 2394561

End: 2395283

Strand: Reverse

Name: resD [H]

Synonym: BLi02458

Alternate gene names: 52786197

Gene position: 2395283-2394561 (Counterclockwise)

Preceding gene: 52786198

Following gene: 52786196

Centisome position: 56.72

GC content: 45.64

Gene sequence:

>723_bases
ATGGAACAGACGAAAGAGACAAAAATATTAGTAGTAGATGATGAGGCAAGAATCAGACGACTTTTAAAAATGTACCTTGA
AAGGGAAAACTACAAGATCGAAGAAGCCGAGAATGGCGATGAAGCCATCGACAAAGCCCTCGGCAACGATTACGATTTAA
TCCTGCTCGATTTGATGATGCCGGGAACCGACGGCATTGAAGTATGCCGCCAAGTACGCGATAAAAAAGCCACTCCGATC
ATCATGCTGACGGCGAAAGGCGAAGAAGCGAACCGGGTGCAGGGCTTTGAAGTCGGAACCGATGACTACATTGTGAAACC
TTTCAGTCCGAGGGAAGTGGTGCTGAGAGTCAAGGCGCTCCTAAGAAGATCATCGCAAACCTCTTACCTGAATACGGATA
CAACGGCAAAAAATGTGCTTGTTTTTTCTCACTTATCCATTGATCACGATGCTCACAGAGTCATGGCGGACGGAACGGAA
GTCAGCCTGACGCCGAAAGAATACGAACTGCTTTACTTTCTGGCCAAAACTCCTGATAAAGTATACGATCGTGAAAAGCT
GCTGAAGGAAGTATGGCAATACGAGTTTTTCGGCGACTTGAGAACGGTCGATACCCATGTTAAACGTTTACGTGAAAAAT
TGAACAAAGTCTCGCCGAAAGCTGCGAAAAAAATCGTAACAGTATGGGGCGTCGGGTATAAATTTGAGGTCGGAAACGAA
TGA

Upstream 100 bases:

>100_bases
CAGCTTTTTGTTTTAAATTGAGGAAAGGCATTCTTGGCTTGGCTTACAATCGCTTTTCTAATAAAATGAATGTAAGAAGA
TTCAAATCAGGAGGTTTACG

Downstream 100 bases:

>100_bases
AGTTTTGGAAGAGCGTAGTCGGTAAACTGTGGTTTACCATACTGCTTTTGGTTTCATTTGTCTTATTTATCCTTACGTTC
TTTCTGCTCGAGTTTATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MEQTKETKILVVDDEARIRRLLKMYLERENYKIEEAENGDEAIDKALGNDYDLILLDLMMPGTDGIEVCRQVRDKKATPI
IMLTAKGEEANRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRSSQTSYLNTDTTAKNVLVFSHLSIDHDAHRVMADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPKAAKKIVTVWGVGYKFEVGNE

Sequences:

>Translated_240_residues
MEQTKETKILVVDDEARIRRLLKMYLERENYKIEEAENGDEAIDKALGNDYDLILLDLMMPGTDGIEVCRQVRDKKATPI
IMLTAKGEEANRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRSSQTSYLNTDTTAKNVLVFSHLSIDHDAHRVMADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPKAAKKIVTVWGVGYKFEVGNE
>Mature_240_residues
MEQTKETKILVVDDEARIRRLLKMYLERENYKIEEAENGDEAIDKALGNDYDLILLDLMMPGTDGIEVCRQVRDKKATPI
IMLTAKGEEANRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRSSQTSYLNTDTTAKNVLVFSHLSIDHDAHRVMADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPKAAKKIVTVWGVGYKFEVGNE

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=42.2413793103448, Blast_Score=183, Evalue=7e-48,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=41.7391304347826, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.5217391304348, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=37.280701754386, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=37.719298245614, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.0689655172414, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.6521739130435, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.2631578947368, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=208, Percent_Identity=38.9423076923077, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=34.3347639484979, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=32.7433628318584, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=31.6239316239316, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=31.8965517241379, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=29.7413793103448, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=34.8623853211009, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=220, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=111, Percent_Identity=31.5315315315315, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=106, Percent_Identity=33.9622641509434, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27676; Mature: 27676

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTKETKILVVDDEARIRRLLKMYLERENYKIEEAENGDEAIDKALGNDYDLILLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHCCCCCEEEEEEEC
PGTDGIEVCRQVRDKKATPIIMLTAKGEEANRVQGFEVGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEECEEECCCCEEECCCCHHHHHHHHHHH
LRRSSQTSYLNTDTTAKNVLVFSHLSIDHDAHRVMADGTEVSLTPKEYELLYFLAKTPDK
HHCCCCCCEECCCCCCCEEEEEEEECCCCCHHHHEECCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPKAAKKIVTVWGVGYKFEVGNE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHEEHEECCCEEEECCCC
>Mature Secondary Structure
MEQTKETKILVVDDEARIRRLLKMYLERENYKIEEAENGDEAIDKALGNDYDLILLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHCCCCCEEEEEEEC
PGTDGIEVCRQVRDKKATPIIMLTAKGEEANRVQGFEVGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEECEEECCCCEEECCCCHHHHHHHHHHH
LRRSSQTSYLNTDTTAKNVLVFSHLSIDHDAHRVMADGTEVSLTPKEYELLYFLAKTPDK
HHCCCCCCEECCCCCCCEEEEEEEECCCCCHHHHEECCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPKAAKKIVTVWGVGYKFEVGNE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHEEHEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]