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The map label for this gene is yycF [H]

Identifier: 52786195

GI number: 52786195

Start: 2391629

End: 2392330

Strand: Reverse

Name: yycF [H]

Synonym: BLi02455

Alternate gene names: 52786195

Gene position: 2392330-2391629 (Counterclockwise)

Preceding gene: 52786196

Following gene: 52786194

Centisome position: 56.65

GC content: 44.02

Gene sequence:

>702_bases
ATGGAAAAAACAAAAATACTGATTATTGAAGATGATGAAGCAATTGCTGATTTGCTTTCATACGGGCTGACGTCCGAAGG
CTTTGAAACGTGCACGGTCAATAACGGTTCTTCAGGAATGAGGAAACTAGATCAGTTCAAACCTGACCTTCTGCTCCTCG
ATTGGATGCTGCCGGACTGCAGCGGATTGGATATTTGCAAAAAAGTGACCGAAAGCTGTAATATTCCAATACTGATGATT
ACCGCAAAATCAGATATCACGGATAAAATACTGGGGTTGGAATTCGGGGCCGATGACTATATTACAAAGCCGTTTGATCT
GCGCGAAGTTGTCGCGAGAATACGCACGATCCTTCGGCGTCTGGAACAAGCCCATCATGTGAACGAACGGGAAACGGAAA
AAGTGGATGAGATCCGGTTTAAAAATATTGTGATCGTTCCGGGCGAAAGACTGGTGAAAAAAGACGGGGCAGCCGTCGAA
TTAACTCCTAAAGAATATGATCTGCTAATGACTTTGGTTGACCATCGGGGAAAAGTTTTTACCCGTTCAGAGCTTTTGGA
ATTCATCTGGGGATACGATTTTTTCGGTGACACCCGTACAGTCGATACCCATATTCAAAGACTCCGCAAAAAGCTTGATG
CAAGCGACTTGATTAAAACAGTGTTCGGCATCGGATATAAATTCGAGAAGCAGGAGGAGTAG

Upstream 100 bases:

>100_bases
CTTTGGTTTGGATTTATGTATAATCTCTATAGAAGGATGCGAGAAACAAAAGAGATTTTTTAGATAAAATAAGCATGAAA
CAGGGAATGAGTGATGACTG

Downstream 100 bases:

>100_bases
AGAGTGTTACGGACCATCAAGGGCAAGTTTATTGTTGGCTTTTTTCTGATTTTTTCTCTCTCTTTCCTTGTGCTCAATCA
CACGGTTAAGAACGTCATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MEKTKILIIEDDEAIADLLSYGLTSEGFETCTVNNGSSGMRKLDQFKPDLLLLDWMLPDCSGLDICKKVTESCNIPILMI
TAKSDITDKILGLEFGADDYITKPFDLREVVARIRTILRRLEQAHHVNERETEKVDEIRFKNIVIVPGERLVKKDGAAVE
LTPKEYDLLMTLVDHRGKVFTRSELLEFIWGYDFFGDTRTVDTHIQRLRKKLDASDLIKTVFGIGYKFEKQEE

Sequences:

>Translated_233_residues
MEKTKILIIEDDEAIADLLSYGLTSEGFETCTVNNGSSGMRKLDQFKPDLLLLDWMLPDCSGLDICKKVTESCNIPILMI
TAKSDITDKILGLEFGADDYITKPFDLREVVARIRTILRRLEQAHHVNERETEKVDEIRFKNIVIVPGERLVKKDGAAVE
LTPKEYDLLMTLVDHRGKVFTRSELLEFIWGYDFFGDTRTVDTHIQRLRKKLDASDLIKTVFGIGYKFEKQEE
>Mature_233_residues
MEKTKILIIEDDEAIADLLSYGLTSEGFETCTVNNGSSGMRKLDQFKPDLLLLDWMLPDCSGLDICKKVTESCNIPILMI
TAKSDITDKILGLEFGADDYITKPFDLREVVARIRTILRRLEQAHHVNERETEKVDEIRFKNIVIVPGERLVKKDGAAVE
LTPKEYDLLMTLVDHRGKVFTRSELLEFIWGYDFFGDTRTVDTHIQRLRKKLDASDLIKTVFGIGYKFEKQEE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=39.4849785407725, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.0869565217391, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=36.6379310344828, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=37.117903930131, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790860, Length=238, Percent_Identity=36.5546218487395, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=36.322869955157, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.920704845815, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.961038961039, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=31.4410480349345, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=32.1888412017167, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.9565217391304, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=29.2576419213974, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=31.4814814814815, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=31.5384615384615, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26749; Mature: 26749

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTKILIIEDDEAIADLLSYGLTSEGFETCTVNNGSSGMRKLDQFKPDLLLLDWMLPDC
CCCCEEEEEECCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCC
SGLDICKKVTESCNIPILMITAKSDITDKILGLEFGADDYITKPFDLREVVARIRTILRR
CCHHHHHHHHHHCCCCEEEEECCCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LEQAHHVNERETEKVDEIRFKNIVIVPGERLVKKDGAAVELTPKEYDLLMTLVDHRGKVF
HHHHHCCCHHHHHHHHHHHHCCEEEECCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEE
TRSELLEFIWGYDFFGDTRTVDTHIQRLRKKLDASDLIKTVFGIGYKFEKQEE
EHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEKTKILIIEDDEAIADLLSYGLTSEGFETCTVNNGSSGMRKLDQFKPDLLLLDWMLPDC
CCCCEEEEEECCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCC
SGLDICKKVTESCNIPILMITAKSDITDKILGLEFGADDYITKPFDLREVVARIRTILRR
CCHHHHHHHHHHCCCCEEEEECCCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LEQAHHVNERETEKVDEIRFKNIVIVPGERLVKKDGAAVELTPKEYDLLMTLVDHRGKVF
HHHHHCCCHHHHHHHHHHHHCCEEEECCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEE
TRSELLEFIWGYDFFGDTRTVDTHIQRLRKKLDASDLIKTVFGIGYKFEKQEE
EHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]