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The map label for this gene is aroE

Identifier: 52786139

GI number: 52786139

Start: 2338635

End: 2339921

Strand: Reverse

Name: aroE

Synonym: BLi02395

Alternate gene names: 52786139

Gene position: 2339921-2338635 (Counterclockwise)

Preceding gene: 52786140

Following gene: 52786138

Centisome position: 55.41

GC content: 53.22

Gene sequence:

>1287_bases
ATGAAAAGAGGAAAAATCAGTTCACTAAAGGGAGAGCTTCATATTCCGGGAGATAAATCCATCTCCCATCGTTCTGTTAT
GTTCGGAGCCATGGCAGAAGGGAAAACGGTCATCAAAAACTTTTTGCCAGGAGCCGACTGCTTGAGCACGATCGCCTGCT
TTCGGAAAATGGGTGTCGAAATCGAACAGAATGGCAGTGATGTCACCGTCCGCGGCAAAGGGCTCGATCAGCTCGCTGAG
CCTGCCGAGCTCCTCGATGTGGGGAATTCCGGAACGACGATCAGGCTGATGCTCGGCATTTTGGCGGGGCGTCCGTTTCA
CAGTACGGTTGCCGGCGATGAGAGCATCGCCAAAAGGCCGATGAAGCGTGTTACAGAACCGCTTCGAAAAATGGGGGCGA
AAATCGACGGCCGCGCCGGAGGGGAATACACACCGCTTTCTGTCCGCGGCGGACATCTGAAGGCGATCGATTTTCAGTCG
CCTGTTGCAAGTGCGCAGATCAAATCGGCCGTTCTGCTTGCGGGTCTGCAGGCCGAAGGCACCACAACGGTGACGGAGCC
TCATAAATCAAGAGACCATACGGAACGGATGCTGTCTATGTTCGGCGTCAGCCTTCGGGAAGATGAAACGAGCGTGTCCA
TTGAGGGCGGGCAGCAGCTGAAAGCAGCAGAAGTCTTTGTGCCGGGTGATATTTCATCAGCTGCGTTTTTCCTGGCAGCA
GCATCGCTTGTTCCTGGCAGTGAAGTCGTGCTTCGCAATGTCGGACTCAATCCGACCAGGACGGGAATCATCGATGTCTT
GAAAGAAATGGGAGCCGATCTTGAAATCGAAGAAAAGGACACAGGAAATACCGAGCCGTACGGCGATCTGAGAATCAAAA
CGTCCTCTTTGAAGGCAGCCGAAATTTCGGGCGATTTGATCCCGCGCCTCATCGATGAAATACCGATCATCGCGCTTCTA
GCAACACAGGCTGAAGGGACGACGGTCATTAAAGATGCGGCTGAACTCAAAGTAAAAGAAACGAACCGGATCGATACCGT
CGCCTCAGAGCTGAAAAAAATCGGTGCGAACATCGAACCGACGGAAGACGGGATGAAGATTCACGGCAAGACGCCTCTTA
CAGGCGGCGCGAAGGTCTCAAGCCATGGGGACCACCGGATCGGAATGATGCTGGGGATCGCCGCCTGCATCTGCGAGCAG
CCGATCGACATATTACAGCCCGAAGCTGTGAGCGTCTCATATCCTTCATTTTTTGAACATATCGAAAAGCTTGCAGAAAA
AGCCTGA

Upstream 100 bases:

>100_bases
AGAATCAGCTTTCAATCCGATGAAGATCGAAAACGCGCCGAAAAATGCATCCAAACCCGCGCAAAATACGAAACATTTTA
TGCTGATTGAGGTGGAACAC

Downstream 100 bases:

>100_bases
AGCATTGTGCTCAGGCTTTTTCTGCCCGGAAAATCATGAAAGCCGGGCATTTGCTCATAAAACGAATGTTTTCGGCATAG
CTTGTCTTAACAGAATCAAT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKRGKISSLKGELHIPGDKSISHRSVMFGAMAEGKTVIKNFLPGADCLSTIACFRKMGVEIEQNGSDVTVRGKGLDQLAE
PAELLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRPMKRVTEPLRKMGAKIDGRAGGEYTPLSVRGGHLKAIDFQS
PVASAQIKSAVLLAGLQAEGTTTVTEPHKSRDHTERMLSMFGVSLREDETSVSIEGGQQLKAAEVFVPGDISSAAFFLAA
ASLVPGSEVVLRNVGLNPTRTGIIDVLKEMGADLEIEEKDTGNTEPYGDLRIKTSSLKAAEISGDLIPRLIDEIPIIALL
ATQAEGTTVIKDAAELKVKETNRIDTVASELKKIGANIEPTEDGMKIHGKTPLTGGAKVSSHGDHRIGMMLGIAACICEQ
PIDILQPEAVSVSYPSFFEHIEKLAEKA

Sequences:

>Translated_428_residues
MKRGKISSLKGELHIPGDKSISHRSVMFGAMAEGKTVIKNFLPGADCLSTIACFRKMGVEIEQNGSDVTVRGKGLDQLAE
PAELLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRPMKRVTEPLRKMGAKIDGRAGGEYTPLSVRGGHLKAIDFQS
PVASAQIKSAVLLAGLQAEGTTTVTEPHKSRDHTERMLSMFGVSLREDETSVSIEGGQQLKAAEVFVPGDISSAAFFLAA
ASLVPGSEVVLRNVGLNPTRTGIIDVLKEMGADLEIEEKDTGNTEPYGDLRIKTSSLKAAEISGDLIPRLIDEIPIIALL
ATQAEGTTVIKDAAELKVKETNRIDTVASELKKIGANIEPTEDGMKIHGKTPLTGGAKVSSHGDHRIGMMLGIAACICEQ
PIDILQPEAVSVSYPSFFEHIEKLAEKA
>Mature_428_residues
MKRGKISSLKGELHIPGDKSISHRSVMFGAMAEGKTVIKNFLPGADCLSTIACFRKMGVEIEQNGSDVTVRGKGLDQLAE
PAELLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRPMKRVTEPLRKMGAKIDGRAGGEYTPLSVRGGHLKAIDFQS
PVASAQIKSAVLLAGLQAEGTTTVTEPHKSRDHTERMLSMFGVSLREDETSVSIEGGQQLKAAEVFVPGDISSAAFFLAA
ASLVPGSEVVLRNVGLNPTRTGIIDVLKEMGADLEIEEKDTGNTEPYGDLRIKTSSLKAAEISGDLIPRLIDEIPIIALL
ATQAEGTTVIKDAAELKVKETNRIDTVASELKKIGANIEPTEDGMKIHGKTPLTGGAKVSSHGDHRIGMMLGIAACICEQ
PIDILQPEAVSVSYPSFFEHIEKLAEKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=438, Percent_Identity=29.4520547945205, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1789580, Length=400, Percent_Identity=25.25, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320332, Length=456, Percent_Identity=26.3157894736842, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_BACLD (Q65I39)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079558.3
- RefSeq:   YP_091968.1
- HSSP:   Q9S400
- ProteinModelPortal:   Q65I39
- SMR:   Q65I39
- STRING:   Q65I39
- EnsemblBacteria:   EBBACT00000057689
- EnsemblBacteria:   EBBACT00000060393
- GeneID:   3029401
- GeneID:   3101463
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02395
- KEGG:   bli:BL02766
- NMPDR:   fig|279010.5.peg.245
- eggNOG:   COG0128
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG646626
- ProtClustDB:   PRK02427
- BioCyc:   BLIC279010-1:BLI02395-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45523; Mature: 45523

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGKISSLKGELHIPGDKSISHRSVMFGAMAEGKTVIKNFLPGADCLSTIACFRKMGVE
CCCCCCCCCCCCEECCCCCCCCHHHHEEHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCE
IEQNGSDVTVRGKGLDQLAEPAELLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRP
EECCCCEEEEECCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHCCCCHHHHHHH
MKRVTEPLRKMGAKIDGRAGGEYTPLSVRGGHLKAIDFQSPVASAQIKSAVLLAGLQAEG
HHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
TTTVTEPHKSRDHTERMLSMFGVSLREDETSVSIEGGQQLKAAEVFVPGDISSAAFFLAA
CEEECCCCCCHHHHHHHHHHHCCEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHH
ASLVPGSEVVLRNVGLNPTRTGIIDVLKEMGADLEIEEKDTGNTEPYGDLRIKTSSLKAA
HHCCCCCHHHEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHH
EISGDLIPRLIDEIPIIALLATQAEGTTVIKDAAELKVKETNRIDTVASELKKIGANIEP
HHCHHHHHHHHHHCCEEEEEEECCCCCEEEEHHHHEEECCCCHHHHHHHHHHHHCCCCCC
TEDGMKIHGKTPLTGGAKVSSHGDHRIGMMLGIAACICEQPIDILQPEAVSVSYPSFFEH
CCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEECCHHHHHH
IEKLAEKA
HHHHHHCC
>Mature Secondary Structure
MKRGKISSLKGELHIPGDKSISHRSVMFGAMAEGKTVIKNFLPGADCLSTIACFRKMGVE
CCCCCCCCCCCCEECCCCCCCCHHHHEEHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCE
IEQNGSDVTVRGKGLDQLAEPAELLDVGNSGTTIRLMLGILAGRPFHSTVAGDESIAKRP
EECCCCEEEEECCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHCCCCHHHHHHH
MKRVTEPLRKMGAKIDGRAGGEYTPLSVRGGHLKAIDFQSPVASAQIKSAVLLAGLQAEG
HHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
TTTVTEPHKSRDHTERMLSMFGVSLREDETSVSIEGGQQLKAAEVFVPGDISSAAFFLAA
CEEECCCCCCHHHHHHHHHHHCCEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHH
ASLVPGSEVVLRNVGLNPTRTGIIDVLKEMGADLEIEEKDTGNTEPYGDLRIKTSSLKAA
HHCCCCCHHHEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHH
EISGDLIPRLIDEIPIIALLATQAEGTTVIKDAAELKVKETNRIDTVASELKKIGANIEP
HHCHHHHHHHHHHCCEEEEEEECCCCCEEEEHHHHEEECCCCHHHHHHHHHHHHCCCCCC
TEDGMKIHGKTPLTGGAKVSSHGDHRIGMMLGIAACICEQPIDILQPEAVSVSYPSFFEH
CCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEECCHHHHHH
IEKLAEKA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA