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The map label for this gene is dapB

Identifier: 52786128

GI number: 52786128

Start: 2329957

End: 2330760

Strand: Reverse

Name: dapB

Synonym: BLi02384

Alternate gene names: 52786128

Gene position: 2330760-2329957 (Counterclockwise)

Preceding gene: 52786129

Following gene: 52786127

Centisome position: 55.2

GC content: 48.51

Gene sequence:

>804_bases
ATGCAAAAGGATACCATTAAAATCGCAATAGCAGGACCGCGCGGAAGAATGGGAAGCGAAGCGGTCAAACTTGTTGAAGA
TACCGCACATTTTGAACTTGTCGGTGCAATCGACCGTACATATAACCGTGAAAAGCTGTCAGATGTGATGACGTCAAGTT
CAGATGCTGTCATTTACACCGATATCACGGAATGCTTTTCAGAAACGTCTCCGGATGTTCTGATTGATTTGACAACGCCG
GAAATCGGCAAGCTACATACAAAAATCGCGTTGGAGCACGGCGTCCGTCCTGTTGTGGGAACGACAGGATTTTCTGAGAG
CGACTTGAACGAGCTTATGGAACTGACCGATGAGAAGGGAATCGGAGCTATCATCGCGCCAAACTTCGCGCTCGGAGCCG
TGCTGATGATGAAGTTTTCGCAAATGGCTGCCAACTATTTTACCGATGTTGAAATCATTGAACAGCACCATGATCAAAAA
CTTGACGCGCCAAGCGGAACGGCCTTGAAAACGGCGGAAATGATTTCGGCTGTTCGCGAAGCGAAAACGCAGGGGCACCC
GGATGAAAAGGAAATTCTGCCGGGAGCAAGAGGCGCCGATCAAAACGGAATCCGTCTCCACAGCGTTCGTCTGCCGGGAT
TGATTGCCCATCAGGAAGTGATGTTCGGCGGAGACGGCCAAACCCTGAAAATCCGTCACGATTCATACAATCGCGCATCT
TTTATGTCTGGTGTGAAACTGGCTGTTGAACAAGTGATGAAAATCGATCAGCTTGTCTACGGCCTTGAAAATATCATAGA
GTAA

Upstream 100 bases:

>100_bases
ATCATTGGATGAAGCGCATGATATGGTCATGGAGAAGTTCAACACCCGTGATAAAGATCGCTGGACAAGAAAAGAAGAAG
GAAAGTAGAGGAGAATCAAG

Downstream 100 bases:

>100_bases
CAAGAAGGGGGAAATCGCTTTGAAAATCGCCTTAATTGCCCATGACCGAAAAAAACAGGATATGATTCAGCTGACGACCG
CTTATAAAGACATTTTAAAA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MQKDTIKIAIAGPRGRMGSEAVKLVEDTAHFELVGAIDRTYNREKLSDVMTSSSDAVIYTDITECFSETSPDVLIDLTTP
EIGKLHTKIALEHGVRPVVGTTGFSESDLNELMELTDEKGIGAIIAPNFALGAVLMMKFSQMAANYFTDVEIIEQHHDQK
LDAPSGTALKTAEMISAVREAKTQGHPDEKEILPGARGADQNGIRLHSVRLPGLIAHQEVMFGGDGQTLKIRHDSYNRAS
FMSGVKLAVEQVMKIDQLVYGLENIIE

Sequences:

>Translated_267_residues
MQKDTIKIAIAGPRGRMGSEAVKLVEDTAHFELVGAIDRTYNREKLSDVMTSSSDAVIYTDITECFSETSPDVLIDLTTP
EIGKLHTKIALEHGVRPVVGTTGFSESDLNELMELTDEKGIGAIIAPNFALGAVLMMKFSQMAANYFTDVEIIEQHHDQK
LDAPSGTALKTAEMISAVREAKTQGHPDEKEILPGARGADQNGIRLHSVRLPGLIAHQEVMFGGDGQTLKIRHDSYNRAS
FMSGVKLAVEQVMKIDQLVYGLENIIE
>Mature_267_residues
MQKDTIKIAIAGPRGRMGSEAVKLVEDTAHFELVGAIDRTYNREKLSDVMTSSSDAVIYTDITECFSETSPDVLIDLTTP
EIGKLHTKIALEHGVRPVVGTTGFSESDLNELMELTDEKGIGAIIAPNFALGAVLMMKFSQMAANYFTDVEIIEQHHDQK
LDAPSGTALKTAEMISAVREAKTQGHPDEKEILPGARGADQNGIRLHSVRLPGLIAHQEVMFGGDGQTLKIRHDSYNRAS
FMSGVKLAVEQVMKIDQLVYGLENIIE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=30.7116104868914, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BACLD (Q65I50)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079548.1
- RefSeq:   YP_091957.1
- ProteinModelPortal:   Q65I50
- SMR:   Q65I50
- STRING:   Q65I50
- EnsemblBacteria:   EBBACT00000055158
- EnsemblBacteria:   EBBACT00000061203
- GeneID:   3029527
- GeneID:   3100733
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02384
- KEGG:   bli:BL02758
- NMPDR:   fig|279010.5.peg.234
- eggNOG:   COG0289
- GeneTree:   EBGT00050000002586
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   BLIC279010-1:BLI02384-MONOMER
- BioCyc:   BLIC279010:BL02758-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29166; Mature: 29166

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDTIKIAIAGPRGRMGSEAVKLVEDTAHFELVGAIDRTYNREKLSDVMTSSSDAVIYT
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEEHHHHHCCHHHHHHHHCCCCCEEEEE
DITECFSETSPDVLIDLTTPEIGKLHTKIALEHGVRPVVGTTGFSESDLNELMELTDEKG
EHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCC
IGAIIAPNFALGAVLMMKFSQMAANYFTDVEIIEQHHDQKLDAPSGTALKTAEMISAVRE
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AKTQGHPDEKEILPGARGADQNGIRLHSVRLPGLIAHQEVMFGGDGQTLKIRHDSYNRAS
HHHCCCCCHHHHCCCCCCCCCCCEEEEEEECCCEEECCEEEECCCCCEEEEECCCCCHHH
FMSGVKLAVEQVMKIDQLVYGLENIIE
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKDTIKIAIAGPRGRMGSEAVKLVEDTAHFELVGAIDRTYNREKLSDVMTSSSDAVIYT
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEEHHHHHCCHHHHHHHHCCCCCEEEEE
DITECFSETSPDVLIDLTTPEIGKLHTKIALEHGVRPVVGTTGFSESDLNELMELTDEKG
EHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCC
IGAIIAPNFALGAVLMMKFSQMAANYFTDVEIIEQHHDQKLDAPSGTALKTAEMISAVRE
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AKTQGHPDEKEILPGARGADQNGIRLHSVRLPGLIAHQEVMFGGDGQTLKIRHDSYNRAS
HHHCCCCCHHHHCCCCCCCCCCCEEEEEEECCCEEECCEEEECCCCCEEEEECCCCCHHH
FMSGVKLAVEQVMKIDQLVYGLENIIE
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA