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The map label for this gene is yprA [H]

Identifier: 52786102

GI number: 52786102

Start: 2305124

End: 2307400

Strand: Reverse

Name: yprA [H]

Synonym: BLi02358

Alternate gene names: 52786102

Gene position: 2307400-2305124 (Counterclockwise)

Preceding gene: 52786103

Following gene: 52786101

Centisome position: 54.64

GC content: 48.57

Gene sequence:

>2277_bases
GTGACAGCGTTGTTTCAAAAACGAAATTTGACAGATATGATTCAGCTTCTGAAAGAAGACCAAGCTTTCAGCAGGCAAAT
TGTTCATTGGCATACAATCGAGGGAAAAGAAGCGGATTACCGCGATTTTCCTGAAGGTTTAGATAAGAGAATCGTGCATG
CTTTACAGCAAAGAGGGATAGAAAAGCTGTATTCCCATCAGGCCGACGCATTTCTGCACAGCGCCGCCGGCAAAAACGTG
ACGCTTGTGACGCCGACGGCATCTGGGAAGACGCTTTGCTACAATCTGCCCGTCATTCAGAGGATCACAGAAGACCAAGA
TGCGCGCAGCTTATACCTTTTTCCTACTAAAGCATTGTCGCAGGACCAAAAAAGCGAACTGAATGAATTAATCGATGAAA
TCGGTGCGTCGATCAACTGTTATACATATGACGGAGATACGTCGCCTTCGATCAGGCAGAAAGTCAGAAAAGCGGGCCAT
ATCGTGATTACAAATCCAGATATGCTGCATTCGGCGATCTTGCCTCACCATACAAAATGGGTGTCATTGTTTGAAAATCT
GAAATACATCGTCATCGATGAGCTTCACGTATACAGGGGAGTCTTTGGCAGCCATGTAGCCAATGTCATCAGACGGCTGA
TGCGGATTGCTGAATTTTATGGAAGCAAGCCGCAGTTTATCTGTACATCCGCGACGATCGCCAATCCATTGGAGCTCGCT
GAGACGCTCACGGGGCAGCCGATGCACCTGATTTCAAACAACGGCGCCCCGTCGGGAAGAAAGCACTTCTTATTTTACAA
CCCGCCGATGGTCAACCGTTCCCTTAACATCAGAAAAAGCGCGACCCTTGAAGTGAGAAAGCTCGCATCCGAATTTCTAA
AAAACGGCATTCAGACGATTGTGTTTGCAAGAAGCAGAGTTCGGGTGGAAATTATATTGACATACTTGCAGGAAGTGATG
AAGCCGATTGTCGGCCCGCATTCGATTCAGGGGTACAGGGGCGGCTATCTGCCGAACGAGCGGCGCGTCATTGAAAAAGG
CCTTCGCAGCGGGGACATCAAAGGCGTTGTCAGCACGAATGCACTCGAACTGGGCGTTGACATCGGACAGCTGCAGACAT
GCATCATGACCGGTTATCCTGGAACGATCTCAAGCGCCTGGCAGCAGGCCGGCCGCGCCGGAAGAAGGCACAACGAAGCG
CTGATTGTCATGGTGGCAAGTTCCGCCCCGCTCGATCAGTACATCGTACAGAATCCGGACTATTTCTTTAAACAAAATCC
CGAGACTGCCGTCATTAACCCGGACAACCTGGTCATTCTCGTCGATCATATCAAATGCGCGGCCTTTGAACTGCCATTCA
AAAGAACGGACACATTCGGCGGTATCGAAATTGAGGATATTCTTGACTACTTGGCAGAAGAAAGGGTCCTCCACTTAACC
GGGAATACGTACCACTGGATGAATGACGCTTTTCCCGCGCACGGCATCAGCTTAAGATCGGCTTCTCAGGAAAATGTTGT
GATTATTGATCAGTCAAGACGCGAGAAGGCGAAAGTAATCGGGGAAATGGACAGGTTCAGCGCCATGACGCTTCTTCACG
ATGAAGCCATTTATTTGCATCAAGGCATCCAATACCAGGTGGAAAAGCTTGACTGGGAGGAGAAAAAGGCGTTTGTCCGC
GAGGTTCAAGTTGATTACTATACCGATGCCAATCTTGCCGTCTTGCTGAGAGTTCTCGAGGTTGACAAGGAGAAAAAGAC
GGAAACCGCAGCGTTCGGTTTTGGGGATGTGACCGTTCAGGCAAAAGCGACGATTTTTAAGAAAATAAAATTTGAGACGC
ATGAAAATATCGGTTCAGGACCGATTCATCTGCCTGAAGAGGAGCTGCATACCAATGCGGCTTGGGTGCAGGTGAACGAT
AGTGAGCGGCAAAATTGGAATGACATCAAATTGGAAGAGGCTTTGCTTGGGACTGCAAACGTTCTTGGGCATGTAGCCGC
CTTAAAAGTGATGTGCGATCCATCTGATCTGCATGTTTTTCCGCAAATCAAAGCCGTTCATAACGAAAAGCCGACGATCT
TTTTGTATGATCGCTATCCCGGCGGAGTGGGTCTTTCACAAAAAGTGTATGAACAAATGCCCGAGATCATCAGTGAAGCG
CATCGGCTGATTTCAAGATGTCCGTGTGAGTCAGGATGCCCTTCCTGCATAGGAGTGAGCGGCGGCGATCAGACAAAAAA
CAATGCTCTGCGCCTTTTAAAAGGCTGGAAAGGTTGA

Upstream 100 bases:

>100_bases
AGTAAAAGAAAAAAGCAGAGAGCGCTTCTCTGCTTTTTCATTTTGTCAGGAAATCACCTCTTTCAGAACGAACGGACATT
CGCTAAAATAGAAGGGAGAG

Downstream 100 bases:

>100_bases
GCGGAATGTCTTTAAAACGAAAACTTAATCGCTATAAGCATCACCTGGGAAATCAAGCGAAAGAAGAAAAAACGGAACCT
CCCGCAGATAAGCTGACTTC

Product: YprA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 757

Protein sequence:

>758_residues
MTALFQKRNLTDMIQLLKEDQAFSRQIVHWHTIEGKEADYRDFPEGLDKRIVHALQQRGIEKLYSHQADAFLHSAAGKNV
TLVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALSQDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGH
IVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELA
ETLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTIVFARSRVRVEIILTYLQEVM
KPIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTNALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEA
LIVMVASSAPLDQYIVQNPDYFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGIEIEDILDYLAEERVLHLT
GNTYHWMNDAFPAHGISLRSASQENVVIIDQSRREKAKVIGEMDRFSAMTLLHDEAIYLHQGIQYQVEKLDWEEKKAFVR
EVQVDYYTDANLAVLLRVLEVDKEKKTETAAFGFGDVTVQAKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVND
SERQNWNDIKLEEALLGTANVLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEA
HRLISRCPCESGCPSCIGVSGGDQTKNNALRLLKGWKG

Sequences:

>Translated_758_residues
MTALFQKRNLTDMIQLLKEDQAFSRQIVHWHTIEGKEADYRDFPEGLDKRIVHALQQRGIEKLYSHQADAFLHSAAGKNV
TLVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALSQDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGH
IVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELA
ETLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTIVFARSRVRVEIILTYLQEVM
KPIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTNALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEA
LIVMVASSAPLDQYIVQNPDYFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGIEIEDILDYLAEERVLHLT
GNTYHWMNDAFPAHGISLRSASQENVVIIDQSRREKAKVIGEMDRFSAMTLLHDEAIYLHQGIQYQVEKLDWEEKKAFVR
EVQVDYYTDANLAVLLRVLEVDKEKKTETAAFGFGDVTVQAKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVND
SERQNWNDIKLEEALLGTANVLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEA
HRLISRCPCESGCPSCIGVSGGDQTKNNALRLLKGWKG
>Mature_757_residues
TALFQKRNLTDMIQLLKEDQAFSRQIVHWHTIEGKEADYRDFPEGLDKRIVHALQQRGIEKLYSHQADAFLHSAAGKNVT
LVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALSQDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGHI
VITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELAE
TLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTIVFARSRVRVEIILTYLQEVMK
PIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTNALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEAL
IVMVASSAPLDQYIVQNPDYFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGIEIEDILDYLAEERVLHLTG
NTYHWMNDAFPAHGISLRSASQENVVIIDQSRREKAKVIGEMDRFSAMTLLHDEAIYLHQGIQYQVEKLDWEEKKAFVRE
VQVDYYTDANLAVLLRVLEVDKEKKTETAAFGFGDVTVQAKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVNDS
ERQNWNDIKLEEALLGTANVLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEAH
RLISRCPCESGCPSCIGVSGGDQTKNNALRLLKGWKG

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320497, Length=776, Percent_Identity=32.3453608247423, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321360, Length=347, Percent_Identity=25.0720461095101, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 85303; Mature: 85171

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFQKRNLTDMIQLLKEDQAFSRQIVHWHTIEGKEADYRDFPEGLDKRIVHALQQRGI
CCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHCHHHHHHHHHHHHHHHHH
EKLYSHQADAFLHSAAGKNVTLVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALS
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECHHHHHHCCCCCCCEEEEEECHHHC
QDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGHIVITNPDMLHSAILPHHTKW
CHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHH
VSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELA
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCHHHHH
ETLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTI
HHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEE
VFARSRVRVEIILTYLQEVMKPIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECC
ALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEALIVMVASSAPLDQYIVQNPD
EEEECCCHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCC
YFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGIEIEDILDYLAEERVLHLT
HHCCCCCCEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCEEEEE
GNTYHWMNDAFPAHGISLRSASQENVVIIDQSRREKAKVIGEMDRFSAMTLLHDEAIYLH
CCEEEECCCCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEC
QGIQYQVEKLDWEEKKAFVREVQVDYYTDANLAVLLRVLEVDKEKKTETAAFGFGDVTVQ
CCCHHHHHHCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCHHCCHHHEECCCCEEEE
AKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVNDSERQNWNDIKLEEALLGTAN
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
VLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEA
HHHHHHHHEEEECCCCCEECCCHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
HRLISRCPCESGCPSCIGVSGGDQTKNNALRLLKGWKG
HHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TALFQKRNLTDMIQLLKEDQAFSRQIVHWHTIEGKEADYRDFPEGLDKRIVHALQQRGI
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHCHHHHHHHHHHHHHHHHH
EKLYSHQADAFLHSAAGKNVTLVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALS
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECHHHHHHCCCCCCCEEEEEECHHHC
QDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGHIVITNPDMLHSAILPHHTKW
CHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHH
VSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELA
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCHHHHH
ETLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTI
HHHCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEE
VFARSRVRVEIILTYLQEVMKPIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECC
ALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEALIVMVASSAPLDQYIVQNPD
EEEECCCHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCC
YFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGIEIEDILDYLAEERVLHLT
HHCCCCCCEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCEEEEE
GNTYHWMNDAFPAHGISLRSASQENVVIIDQSRREKAKVIGEMDRFSAMTLLHDEAIYLH
CCEEEECCCCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEC
QGIQYQVEKLDWEEKKAFVREVQVDYYTDANLAVLLRVLEVDKEKKTETAAFGFGDVTVQ
CCCHHHHHHCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCHHCCHHHEECCCCEEEE
AKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVNDSERQNWNDIKLEEALLGTAN
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
VLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEA
HHHHHHHHEEEECCCCCEECCCHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
HRLISRCPCESGCPSCIGVSGGDQTKNNALRLLKGWKG
HHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]