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The map label for this gene is yfnA [H]

Identifier: 52785951

GI number: 52785951

Start: 2162385

End: 2163722

Strand: Direct

Name: yfnA [H]

Synonym: BLi02203

Alternate gene names: 52785951

Gene position: 2162385-2163722 (Clockwise)

Preceding gene: 52785948

Following gene: 52785952

Centisome position: 51.21

GC content: 49.03

Gene sequence:

>1338_bases
TTGAAAAACGAAACTGCGCTTAAACGAAGCCTTACACTCGGCCCGCTCGTTGTGATCGGCCTTGCTTATATGGACCCGCT
CGTCGTATTTGATTCCTACGGAGTTGTCGCACAGCTGACAAAGGGACACGTTCCGGCGGCATACGTATTCACTGTTGCCG
CCCTCCTTTTGACCGCTTTGAGCTACGGCAGCATGGTCAAAGCTTACCCTAAAGCGGGATCGGTTTATACTTATGCATAT
GAAAGCATTCATCCGCATGCGGGATTTTTAGCCGGCTGGACGATCATGCTGGACTATTTGTTTTTGCCGATGGTCAACTT
TGCGATCGGCAGCGCTTATTTAACGGCGGCTTTTCCAGAAGTGCCGCATGGTTTTTGGGTCGTTCTGCTCGCTCTATCCA
TCACTGTCGTCAATGTTTTAGGCATCAGACTAACGGCAAATATTACAGGGCTGTTCGTCGCTTTTCAAGTGATCGTCGCC
CTGACTTTTGCCGGATTTATGATCGCCGGGCTGGCAGGCGGCCTCGGGACGGGCGAGCTGATTTCTGCCGATCCGTTTTT
CCATTCTGATATCGAACCTTCCCTGATTGTGTCAGGGGCGACGATTTTGTGTTTTTCGTTTCTCGGTTTTGATGCGATCT
CTACAATGTCTGAAGAAACGGTCAACCCGAAGAAAAACATTCCGTTAGCCATCTTTCTAACAGTAGCGATCGGCGGAACG
CTGTTCACGGCGATTTCTTATTTGATGCAGCAAATCTATCCGTCCTATGATAACTTCCGGCATGCCGATTCGGCATCGCT
GGAAATAGCCCTATATACGGGAGGCGCTTTTTTAAAGTCCTTCTTTCTGGCGGGAACGATGGTCGCAGTCATTTCATCCT
CGCTCTCTTCGCATGCGAGCGCTTCGCGGCTTTTGTATGCAATGGGGCGTGACAGCTCTCTTCCGAAACGCTTTTTCGGC
TACGTGCATCCGACTTTAAAGACGCCGGTATTTAATATTTTGTTCATCGGGCTGATTTCTTTGACGGCCATGATCGGGGA
ATTAGAGGTCATCTATTCATTCATCAGTTTCGGCGCGCTGATCGGATTTATTTTTGTCCATTTGTCTGTCATCGGCCATT
ACTACATTCGGAGGCAGGAAAAAGGCTTTTTAAAAACGCTTCGTTATTTGGTTATGCCCTTTTTAGGGGCCTCTTTCTGC
GGCTGGCTGCTGCTTAGCATCAGCAAAAATGCGCTAATAATTGGAGCCGGCTGGCTGATTGCCGGTTTTATATACTTTTT
GTTCAGGATCCGTTCTCTTCCGGACGTCACATTCGGCTTTGATCGCGATCCGCGCTAG

Upstream 100 bases:

>100_bases
ATGCGAAAAAAGAGGTTTTCATACGCTTGCTCAAGCACAAAAAAACAGATAAAATATGTCTTAATTTCTGTATTTTTTAC
ATAAGGGGATTTAGAAGTCA

Downstream 100 bases:

>100_bases
AATGGTATATCGCTTGGTCTTCTTGTAGAGATATGTCATAATAAATGAGACTGTATACTGTTTTGCATCAGGGCGCTACA
GAGGTGAAACCATTGAAGAA

Product: YfnA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYVFTVAALLLTALSYGSMVKAYPKAGSVYTYAY
ESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPEVPHGFWVVLLALSITVVNVLGIRLTANITGLFVAFQVIVA
LTFAGFMIAGLAGGLGTGELISADPFFHSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGT
LFTAISYLMQQIYPSYDNFRHADSASLEIALYTGGAFLKSFFLAGTMVAVISSSLSSHASASRLLYAMGRDSSLPKRFFG
YVHPTLKTPVFNILFIGLISLTAMIGELEVIYSFISFGALIGFIFVHLSVIGHYYIRRQEKGFLKTLRYLVMPFLGASFC
GWLLLSISKNALIIGAGWLIAGFIYFLFRIRSLPDVTFGFDRDPR

Sequences:

>Translated_445_residues
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYVFTVAALLLTALSYGSMVKAYPKAGSVYTYAY
ESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPEVPHGFWVVLLALSITVVNVLGIRLTANITGLFVAFQVIVA
LTFAGFMIAGLAGGLGTGELISADPFFHSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGT
LFTAISYLMQQIYPSYDNFRHADSASLEIALYTGGAFLKSFFLAGTMVAVISSSLSSHASASRLLYAMGRDSSLPKRFFG
YVHPTLKTPVFNILFIGLISLTAMIGELEVIYSFISFGALIGFIFVHLSVIGHYYIRRQEKGFLKTLRYLVMPFLGASFC
GWLLLSISKNALIIGAGWLIAGFIYFLFRIRSLPDVTFGFDRDPR
>Mature_445_residues
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYVFTVAALLLTALSYGSMVKAYPKAGSVYTYAY
ESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPEVPHGFWVVLLALSITVVNVLGIRLTANITGLFVAFQVIVA
LTFAGFMIAGLAGGLGTGELISADPFFHSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGT
LFTAISYLMQQIYPSYDNFRHADSASLEIALYTGGAFLKSFFLAGTMVAVISSSLSSHASASRLLYAMGRDSSLPKRFFG
YVHPTLKTPVFNILFIGLISLTAMIGELEVIYSFISFGALIGFIFVHLSVIGHYYIRRQEKGFLKTLRYLVMPFLGASFC
GWLLLSISKNALIIGAGWLIAGFIYFLFRIRSLPDVTFGFDRDPR

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=26.0969976905312, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI114326544, Length=420, Percent_Identity=26.9047619047619, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI114326550, Length=420, Percent_Identity=26.9047619047619, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=26.1904761904762, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI258614005, Length=420, Percent_Identity=25.2380952380952, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI258614003, Length=420, Percent_Identity=25.2380952380952, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI181337167, Length=388, Percent_Identity=24.7422680412371, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI110347453, Length=394, Percent_Identity=28.4263959390863, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI186910308, Length=364, Percent_Identity=24.7252747252747, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI186910306, Length=364, Percent_Identity=24.7252747252747, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI186910304, Length=364, Percent_Identity=24.7252747252747, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081869, Length=443, Percent_Identity=44.2437923250564, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI87082023, Length=434, Percent_Identity=41.4746543778802, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1786789, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786602, Length=396, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081708, Length=435, Percent_Identity=23.2183908045977, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=400, Percent_Identity=27, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17531343, Length=393, Percent_Identity=25.4452926208651, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=396, Percent_Identity=22.979797979798, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24668806, Length=421, Percent_Identity=26.1282660332542, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356285, Length=421, Percent_Identity=26.1282660332542, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668802, Length=421, Percent_Identity=26.1282660332542, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221512776, Length=424, Percent_Identity=26.1792452830189, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24666159, Length=424, Percent_Identity=26.1792452830189, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667468, Length=414, Percent_Identity=25.8454106280193, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366235, Length=418, Percent_Identity=26.555023923445, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007820, Length=418, Percent_Identity=26.555023923445, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=27.2506082725061, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=27.2506082725061, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357367, Length=366, Percent_Identity=23.4972677595628, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48355; Mature: 48355

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYVFTVAALLLTAL
CCCHHHHHHHCCHHHHHHHHHHHHCHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
SYGSMVKAYPKAGSVYTYAYESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPE
HHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPHGFWVVLLALSITVVNVLGIRLTANITGLFVAFQVIVALTFAGFMIAGLAGGLGTGEL
CCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ISADPFFHSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGT
EECCCCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHH
LFTAISYLMQQIYPSYDNFRHADSASLEIALYTGGAFLKSFFLAGTMVAVISSSLSSHAS
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRLLYAMGRDSSLPKRFFGYVHPTLKTPVFNILFIGLISLTAMIGELEVIYSFISFGAL
HHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFIFVHLSVIGHYYIRRQEKGFLKTLRYLVMPFLGASFCGWLLLSISKNALIIGAGWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
AGFIYFLFRIRSLPDVTFGFDRDPR
HHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYVFTVAALLLTAL
CCCHHHHHHHCCHHHHHHHHHHHHCHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
SYGSMVKAYPKAGSVYTYAYESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPE
HHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPHGFWVVLLALSITVVNVLGIRLTANITGLFVAFQVIVALTFAGFMIAGLAGGLGTGEL
CCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ISADPFFHSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGT
EECCCCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHH
LFTAISYLMQQIYPSYDNFRHADSASLEIALYTGGAFLKSFFLAGTMVAVISSSLSSHAS
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRLLYAMGRDSSLPKRFFGYVHPTLKTPVFNILFIGLISLTAMIGELEVIYSFISFGAL
HHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFIFVHLSVIGHYYIRRQEKGFLKTLRYLVMPFLGASFCGWLLLSISKNALIIGAGWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
AGFIYFLFRIRSLPDVTFGFDRDPR
HHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]