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The map label for this gene is arsC

Identifier: 52785874

GI number: 52785874

Start: 2069066

End: 2069485

Strand: Reverse

Name: arsC

Synonym: BLi02122

Alternate gene names: 52785874

Gene position: 2069485-2069066 (Counterclockwise)

Preceding gene: 52785875

Following gene: 52785872

Centisome position: 49.01

GC content: 51.19

Gene sequence:

>420_bases
ATGTCAAAAAAGACCATCTATTTTTTATGCACAGGCAACTCCTGCCGCAGCCAAATGGCTGAAGGCTGGGCGAAGAAACA
TCTCGGAGACGAGTGGAACGTCTACAGTGCAGGGATTGAAGCGCACGGTTTAAACCCGAACGCAGTCAAAGCCATGCGAG
AAGCAGGCATCGATATTTCTGAGCAGACGTCCGATATCATTGATCCCGATATCTTACACAACGCAGACCTCGTCATTACG
CTGTGCGGGGACGCGGCTGATAAATGCCCGATGACACCGCCGCACGTCAAGCGCGAGCATTGGGGTTTTGACGATCCCGC
CAAAGCAGAAGGGACAGAAGAAGAAAAATGGGCATTCTTTCAGCGTGTACGCGATGAAATTGGAGAGCGGATCAAGCGAT
TTGCGGAGACAGGAGAATAA

Upstream 100 bases:

>100_bases
ACAGGTGTCATTTTGACCATTCCAACCCTGTTCATCACGCTTGCCGGACTTTATGTGTGGCTGCTGATCATCCATTAAAC
ATGATAGGAGACGATGACCA

Downstream 100 bases:

>100_bases
ATGCAAAGCTCAGGTAACAATACCTGAGCTTTGCATTTATTAGAAACATATAAAAACACGTCTGCAACATATATTTTCTA
TAAAGAAAGAACGTACCCTA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MSKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDISEQTSDIIDPDILHNADLVIT
LCGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFFQRVRDEIGERIKRFAETGE

Sequences:

>Translated_139_residues
MSKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDISEQTSDIIDPDILHNADLVIT
LCGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFFQRVRDEIGERIKRFAETGE
>Mature_138_residues
SKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDISEQTSDIIDPDILHNADLVITL
CGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFFQRVRDEIGERIKRFAETGE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARSC_BACLD (Q65IV4)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079285.1
- RefSeq:   YP_091703.1
- ProteinModelPortal:   Q65IV4
- SMR:   Q65IV4
- STRING:   Q65IV4
- EnsemblBacteria:   EBBACT00000056177
- EnsemblBacteria:   EBBACT00000061320
- GeneID:   3031404
- GeneID:   3099922
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02122
- KEGG:   bli:BL01871
- NMPDR:   fig|279010.5.peg.2819
- eggNOG:   COG0394
- GeneTree:   EBGT00070000032125
- HOGENOM:   HBG730979
- OMA:   TVCDGAK
- ProtClustDB:   PRK13530
- BioCyc:   BLIC279010-1:BLI02122-MONOMER
- BioCyc:   BLIC279010:BL01871-MONOMER
- HAMAP:   MF_01624
- InterPro:   IPR014064
- InterPro:   IPR017867
- PANTHER:   PTHR11717
- SMART:   SM00226
- TIGRFAMs:   TIGR02691

Pfam domain/function: PF01451 LMWPc; SSF52788 Tyr_Pase_low_mol_wt

EC number: =3.1.3.48

Molecular weight: Translated: 15594; Mature: 15462

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: ACT_SITE 10-10 ACT_SITE 82-82 ACT_SITE 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDIS
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
EQTSDIIDPDILHNADLVITLCGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFF
HHHHHCCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHH
QRVRDEIGERIKRFAETGE
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKTIYFLCTGNSCRSQMAEGWAKKHLGDEWNVYSAGIEAHGLNPNAVKAMREAGIDIS
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
EQTSDIIDPDILHNADLVITLCGDAADKCPMTPPHVKREHWGFDDPAKAEGTEEEKWAFF
HHHHHCCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHH
QRVRDEIGERIKRFAETGE
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA