Click here to switch to the map view.

The map label for this gene is uxuA2

Identifier: 52785868

GI number: 52785868

Start: 2060733

End: 2061803

Strand: Reverse

Name: uxuA2

Synonym: BLi02116

Alternate gene names: 52785868

Gene position: 2061803-2060733 (Counterclockwise)

Preceding gene: 52785869

Following gene: 52785867

Centisome position: 48.83

GC content: 39.87

Gene sequence:

>1071_bases
ATGCAAATGACGTTTCGATGGTATGGAGACAGCGACCCGGTCACATTAGAGTATATTCGCCAAATTCCCGGCGTTACTGG
AATTGTTTCGGCCATTTATGATATTCCTGTAGGGGAAGCATGGCCTTATGAGAAAATTGTAGAGTTAAAAGAAAAAATTG
AAAATCATGGTTTATCGTTAAGTGTCATTGAAAGTGTACCTGTCCATGAAGATATTAAATTAGGTCTTCCGACAAGAGAT
CAATATATTGAAAACTATAAAACGACGATACGCAACTTGGCAAAAGCCGGTGTTAAAATCGTTTGTTATAATTTCATGCC
GGTCTTTGACTGGACCCGTTCTTCTTTAGACTATGCACTAGAAGACGGTTCTACAGCATTAATTTATGAAGAAGAAAAAG
TTAGACAAATGAATCCATTACATGGTGAACTAAAACTTCCCGGTTGGGACACAAGCTATGAAGATGGACAGCTAAAGAAT
CTTTTTCAACAATATCAGCACATGACGGAAGAGGATTTATGGGAAAATCTTTCGTATTTTATTAAAGCGGTTATACCGGC
GGCAGAAAATGAACAAGTCAAAATGGCGATTCACCCGGATGATCCGCCATGGCCTATCTTTGGACTGCCTCGAATCATAA
CGAACAAAGAGAATTTGGAGCGATTGATTCATCTCTATGACAGCTCCTTTAACGGTTTGTGTTTATGCAGCGGGTCACTG
GGTGTGAAGTCAACAAATGATATTCCGGAATTGATTCGTTATTTCGGAAAAAAAGGAAAAGTTAACTTTGTGCACCTGAG
AAACATTAAGATCATCGGGGAAAAGTCATTTCAAGAATCCTCCCACCGTTCAGAAGACGGTTCTTTAGATATGTATGAAA
TCGTAAGAGCATTAAGAGATATAGATTTTGCCGGACCAGCCAGACCGGATCATGGAAGGATGATTTGGGGAGAGACCGGA
AAACCGGGTTATGGTTTATATGACCGGGCGCTTGGTGCAGTGTATTTAAATGGAATGTGGGAAACATTGACGAAAGAAAA
GAAGCGGATAGCCTTAGAATGCAATAAATGA

Upstream 100 bases:

>100_bases
CGGCAAATTCTTTGAAAAAAATCGTTCCAATATATTGTTATTTCATGCGAAATGATGATATCGAATGTTAAATAATAAGA
GGGAAGAGGATGGGGGAACC

Downstream 100 bases:

>100_bases
ACAAGCACTAACTAAAATGCAGAGACGAGGGATAAATGTGCAGATTCCTTTTCATGTCAACTTGAAAGATAAGGTGGCTG
TAGTGACAGGTGGAAGCGGC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase 2

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQMTFRWYGDSDPVTLEYIRQIPGVTGIVSAIYDIPVGEAWPYEKIVELKEKIENHGLSLSVIESVPVHEDIKLGLPTRD
QYIENYKTTIRNLAKAGVKIVCYNFMPVFDWTRSSLDYALEDGSTALIYEEEKVRQMNPLHGELKLPGWDTSYEDGQLKN
LFQQYQHMTEEDLWENLSYFIKAVIPAAENEQVKMAIHPDDPPWPIFGLPRIITNKENLERLIHLYDSSFNGLCLCSGSL
GVKSTNDIPELIRYFGKKGKVNFVHLRNIKIIGEKSFQESSHRSEDGSLDMYEIVRALRDIDFAGPARPDHGRMIWGETG
KPGYGLYDRALGAVYLNGMWETLTKEKKRIALECNK

Sequences:

>Translated_356_residues
MQMTFRWYGDSDPVTLEYIRQIPGVTGIVSAIYDIPVGEAWPYEKIVELKEKIENHGLSLSVIESVPVHEDIKLGLPTRD
QYIENYKTTIRNLAKAGVKIVCYNFMPVFDWTRSSLDYALEDGSTALIYEEEKVRQMNPLHGELKLPGWDTSYEDGQLKN
LFQQYQHMTEEDLWENLSYFIKAVIPAAENEQVKMAIHPDDPPWPIFGLPRIITNKENLERLIHLYDSSFNGLCLCSGSL
GVKSTNDIPELIRYFGKKGKVNFVHLRNIKIIGEKSFQESSHRSEDGSLDMYEIVRALRDIDFAGPARPDHGRMIWGETG
KPGYGLYDRALGAVYLNGMWETLTKEKKRIALECNK
>Mature_356_residues
MQMTFRWYGDSDPVTLEYIRQIPGVTGIVSAIYDIPVGEAWPYEKIVELKEKIENHGLSLSVIESVPVHEDIKLGLPTRD
QYIENYKTTIRNLAKAGVKIVCYNFMPVFDWTRSSLDYALEDGSTALIYEEEKVRQMNPLHGELKLPGWDTSYEDGQLKN
LFQQYQHMTEEDLWENLSYFIKAVIPAAENEQVKMAIHPDDPPWPIFGLPRIITNKENLERLIHLYDSSFNGLCLCSGSL
GVKSTNDIPELIRYFGKKGKVNFVHLRNIKIIGEKSFQESSHRSEDGSLDMYEIVRALRDIDFAGPARPDHGRMIWGETG
KPGYGLYDRALGAVYLNGMWETLTKEKKRIALECNK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=388, Percent_Identity=38.1443298969072, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA2_BACLD (Q65IW0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079279.2
- RefSeq:   YP_091697.1
- ProteinModelPortal:   Q65IW0
- SMR:   Q65IW0
- STRING:   Q65IW0
- EnsemblBacteria:   EBBACT00000054395
- EnsemblBacteria:   EBBACT00000061779
- GeneID:   3031397
- GeneID:   3101007
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02116
- KEGG:   bli:BL00281
- NMPDR:   fig|279010.5.peg.2813
- eggNOG:   COG1312
- GeneTree:   EBGT00050000001836
- HOGENOM:   HBG585927
- ProtClustDB:   PRK03906
- BioCyc:   BLIC279010-1:BLI02116-MONOMER
- BioCyc:   BLIC279010:BL00281-MONOMER
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 40830; Mature: 40830

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMTFRWYGDSDPVTLEYIRQIPGVTGIVSAIYDIPVGEAWPYEKIVELKEKIENHGLSL
CCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEE
SVIESVPVHEDIKLGLPTRDQYIENYKTTIRNLAKAGVKIVCYNFMPVFDWTRSSLDYAL
EEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEECEEHHHHHHHHHHHHC
EDGSTALIYEEEKVRQMNPLHGELKLPGWDTSYEDGQLKNLFQQYQHMTEEDLWENLSYF
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
IKAVIPAAENEQVKMAIHPDDPPWPIFGLPRIITNKENLERLIHLYDSSFNGLCLCSGSL
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEECCCC
GVKSTNDIPELIRYFGKKGKVNFVHLRNIKIIGEKSFQESSHRSEDGSLDMYEIVRALRD
CCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHC
IDFAGPARPDHGRMIWGETGKPGYGLYDRALGAVYLNGMWETLTKEKKRIALECNK
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MQMTFRWYGDSDPVTLEYIRQIPGVTGIVSAIYDIPVGEAWPYEKIVELKEKIENHGLSL
CCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEE
SVIESVPVHEDIKLGLPTRDQYIENYKTTIRNLAKAGVKIVCYNFMPVFDWTRSSLDYAL
EEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEECEEHHHHHHHHHHHHC
EDGSTALIYEEEKVRQMNPLHGELKLPGWDTSYEDGQLKNLFQQYQHMTEEDLWENLSYF
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
IKAVIPAAENEQVKMAIHPDDPPWPIFGLPRIITNKENLERLIHLYDSSFNGLCLCSGSL
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEECCCC
GVKSTNDIPELIRYFGKKGKVNFVHLRNIKIIGEKSFQESSHRSEDGSLDMYEIVRALRD
CCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHC
IDFAGPARPDHGRMIWGETGKPGYGLYDRALGAVYLNGMWETLTKEKKRIALECNK
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA