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The map label for this gene is trxB [H]

Identifier: 52785845

GI number: 52785845

Start: 2033938

End: 2034855

Strand: Reverse

Name: trxB [H]

Synonym: BLi02092

Alternate gene names: 52785845

Gene position: 2034855-2033938 (Counterclockwise)

Preceding gene: 52785846

Following gene: 52785844

Centisome position: 48.19

GC content: 51.09

Gene sequence:

>918_bases
ATGAAAAAACAACTTCTCGATGTAGCGATTATTGGGGGAGGTCCAGCAGGGTTGAATGCCGCCCTTGTTCTTGGGCGTGC
GAGGAAAAATGTGGCGGTGATCGATGCAGGCCGGCCACGCAACGCCGTTACTCGCAAAGCTCACGGATTTCTTACCCGTG
ACGGAATAAGCCCAAGTGAATTTCGGCAAATTGCAAAGGAACAGATCAGTGCATATCCCTCCGTGTCTTTTATAGCGGAT
AAAGCTGTGTCGATTACAAAAACCGGCGGTCATTTTCAAATGACAACTGCGCAAGGAAACACTTTTGCAAGCAAGAAAGT
GCTGTTTGCCGTCGGAATGAAGGATCAGCCGCTAGATATTCCAGGGCTGGCAGAGGTTTATGGGAAGAGCGCCTTCGTCT
GCCCGTACTGTGATGGCTGGGAATTAAGGGATAAGCCTCTAGTGATCATTACCAAGGGGGACGAGGCCATTCACTTCGCT
TCTCTCATATCAGGATGGACGAACCGTTTTACGATTTGCACGAACGGCCCCCATCAACTGACGGACGAGCAGTGCGAGGA
GCTCAGCAGGCATCGCGTCCCTGTATTCGAAGCGCCGATTCGATGCATCGACTCAGACGACGGGATCGTGCAACAAGTCG
TTCTCGAAGACGGGACGACAATTCCATGTAAGGGAATCTTTTTTAAAACGGAACTTGTGACAGGATCGGATTTACCGCGA
GCCATAGGATGCGACATCACAGAATCGGGAACGGTCGTCGTTGATAACTTTGGGAAAACGAATATACCGGGCATCTATAG
TGCAGGCGATGCAGCTACGAAATTGCATCAAGCCGTTGTCGCCGCCTCGATGGGTGCTATGGCCGCCGCGGCCATAAACA
ATGAACTGAATTTGGAGGCTTGGGAGCAAAACGGATGA

Upstream 100 bases:

>100_bases
AAAGTTCTGATCCGATTACAGAATCAGAACATGTACATGAATTCATGACGACACAGCAATTAATTATAGATATTAAAGAT
CTATGGAGGTTCTTAAATAC

Downstream 100 bases:

>100_bases
AAACTTTCTGATACTCAAATGTCCAAAATTAAAAGAGCCATACTTTAAGTCAGAAGAAAATAGGGGTGTATGTTGACATA
TGTAGAGGTGAAATGCCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKQLLDVAIIGGGPAGLNAALVLGRARKNVAVIDAGRPRNAVTRKAHGFLTRDGISPSEFRQIAKEQISAYPSVSFIAD
KAVSITKTGGHFQMTTAQGNTFASKKVLFAVGMKDQPLDIPGLAEVYGKSAFVCPYCDGWELRDKPLVIITKGDEAIHFA
SLISGWTNRFTICTNGPHQLTDEQCEELSRHRVPVFEAPIRCIDSDDGIVQQVVLEDGTTIPCKGIFFKTELVTGSDLPR
AIGCDITESGTVVVDNFGKTNIPGIYSAGDAATKLHQAVVAASMGAMAAAAINNELNLEAWEQNG

Sequences:

>Translated_305_residues
MKKQLLDVAIIGGGPAGLNAALVLGRARKNVAVIDAGRPRNAVTRKAHGFLTRDGISPSEFRQIAKEQISAYPSVSFIAD
KAVSITKTGGHFQMTTAQGNTFASKKVLFAVGMKDQPLDIPGLAEVYGKSAFVCPYCDGWELRDKPLVIITKGDEAIHFA
SLISGWTNRFTICTNGPHQLTDEQCEELSRHRVPVFEAPIRCIDSDDGIVQQVVLEDGTTIPCKGIFFKTELVTGSDLPR
AIGCDITESGTVVVDNFGKTNIPGIYSAGDAATKLHQAVVAASMGAMAAAAINNELNLEAWEQNG
>Mature_305_residues
MKKQLLDVAIIGGGPAGLNAALVLGRARKNVAVIDAGRPRNAVTRKAHGFLTRDGISPSEFRQIAKEQISAYPSVSFIAD
KAVSITKTGGHFQMTTAQGNTFASKKVLFAVGMKDQPLDIPGLAEVYGKSAFVCPYCDGWELRDKPLVIITKGDEAIHFA
SLISGWTNRFTICTNGPHQLTDEQCEELSRHRVPVFEAPIRCIDSDDGIVQQVVLEDGTTIPCKGIFFKTELVTGSDLPR
AIGCDITESGTVVVDNFGKTNIPGIYSAGDAATKLHQAVVAASMGAMAAAAINNELNLEAWEQNG

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=220, Percent_Identity=23.6363636363636, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=23.8853503184713, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32574; Mature: 32574

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQLLDVAIIGGGPAGLNAALVLGRARKNVAVIDAGRPRNAVTRKAHGFLTRDGISPSE
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHCCCEEECCCCHHH
FRQIAKEQISAYPSVSFIADKAVSITKTGGHFQMTTAQGNTFASKKVLFAVGMKDQPLDI
HHHHHHHHHHCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCCCC
PGLAEVYGKSAFVCPYCDGWELRDKPLVIITKGDEAIHFASLISGWTNRFTICTNGPHQL
CCHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCC
TDEQCEELSRHRVPVFEAPIRCIDSDDGIVQQVVLEDGTTIPCKGIFFKTELVTGSDLPR
CHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCH
AIGCDITESGTVVVDNFGKTNIPGIYSAGDAATKLHQAVVAASMGAMAAAAINNELNLEA
HHCCCCCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WEQNG
ECCCC
>Mature Secondary Structure
MKKQLLDVAIIGGGPAGLNAALVLGRARKNVAVIDAGRPRNAVTRKAHGFLTRDGISPSE
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHCCCEEECCCCHHH
FRQIAKEQISAYPSVSFIADKAVSITKTGGHFQMTTAQGNTFASKKVLFAVGMKDQPLDI
HHHHHHHHHHCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCCCC
PGLAEVYGKSAFVCPYCDGWELRDKPLVIITKGDEAIHFASLISGWTNRFTICTNGPHQL
CCHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCC
TDEQCEELSRHRVPVFEAPIRCIDSDDGIVQQVVLEDGTTIPCKGIFFKTELVTGSDLPR
CHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCH
AIGCDITESGTVVVDNFGKTNIPGIYSAGDAATKLHQAVVAASMGAMAAAAINNELNLEA
HHCCCCCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WEQNG
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]