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The map label for this gene is fnr [H]

Identifier: 52785837

GI number: 52785837

Start: 2024197

End: 2024865

Strand: Direct

Name: fnr [H]

Synonym: BLi02083

Alternate gene names: 52785837

Gene position: 2024197-2024865 (Clockwise)

Preceding gene: 52785836

Following gene: 52785838

Centisome position: 47.94

GC content: 43.5

Gene sequence:

>669_bases
ATGGAGTTTCTGAAGCAATTTATGATTTTCAGCGGGTTGAATGATGAAGAGTTCAAGCAAATCGAGCAGATCGCGGCCAA
GCGCACCTATCAGCCGAGAATGTTTGTTTTTATGGAGGGGGAAGAGAGGGAAGCGGTATTTTTCATCAAATCCGGTCTTG
TTAAAGCCTTTAAAATCGATGAAGACGGCAATGAACAAGTGATTTCGATTCTGCAAAACGGGGATATGTTTCCCCATGTC
GGCTTTTTTGACCTCTCCCCATACCCGGCAACGGCAGAAGCCGTTCAAGAAACCGAATTGATCGTAATCCGCATCGCCGA
TTTTAATGAACTTTTGATGAAATTTCCGGAAATGACGATAAAAGTGATGCAAATCATGGGGAAAAAGATTCTCGATTTGC
AAGAGCGGATCCAGGGTTTTATCTCAAAAGACGTCCAGCACCGCTTGACACATGTATTAATGAAGCTTGCTGCTGAACAT
GGCATTCCTCAAGAAAAAGGGGTCTACATCAGCCTGCCCATTACCAATCAGGATTTTGCGAACATGGTCGGAACGTCAAG
GGAAACGATTAACCGCACATTAAATGAATTGAAAAAGAAAAATCTGCTGACAGCTGACAGGAGCGGAATTTTCATTCATG
ATACAGACTGGCTGAACGGCTGCAATTAA

Upstream 100 bases:

>100_bases
GAAGAGAAGGCAGCGGCGATTGAAGAAGAGCTCTTTGCACTGGAGCGCCGTCTGTGACAAACCGCTCTCCTTTAGCAAAA
CCGAAGGGATTGAAAGACCA

Downstream 100 bases:

>100_bases
GGCATGAGTTTTAGGCTTTCCATTGAACGGCAGATGGAAAGCCTGTTTTTTATTTTGTTCACAAATACGCCATGATTTAA
GTGATCTGGTTCACAACTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MEFLKQFMIFSGLNDEEFKQIEQIAAKRTYQPRMFVFMEGEEREAVFFIKSGLVKAFKIDEDGNEQVISILQNGDMFPHV
GFFDLSPYPATAEAVQETELIVIRIADFNELLMKFPEMTIKVMQIMGKKILDLQERIQGFISKDVQHRLTHVLMKLAAEH
GIPQEKGVYISLPITNQDFANMVGTSRETINRTLNELKKKNLLTADRSGIFIHDTDWLNGCN

Sequences:

>Translated_222_residues
MEFLKQFMIFSGLNDEEFKQIEQIAAKRTYQPRMFVFMEGEEREAVFFIKSGLVKAFKIDEDGNEQVISILQNGDMFPHV
GFFDLSPYPATAEAVQETELIVIRIADFNELLMKFPEMTIKVMQIMGKKILDLQERIQGFISKDVQHRLTHVLMKLAAEH
GIPQEKGVYISLPITNQDFANMVGTSRETINRTLNELKKKNLLTADRSGIFIHDTDWLNGCN
>Mature_222_residues
MEFLKQFMIFSGLNDEEFKQIEQIAAKRTYQPRMFVFMEGEEREAVFFIKSGLVKAFKIDEDGNEQVISILQNGDMFPHV
GFFDLSPYPATAEAVQETELIVIRIADFNELLMKFPEMTIKVMQIMGKKILDLQERIQGFISKDVQHRLTHVLMKLAAEH
GIPQEKGVYISLPITNQDFANMVGTSRETINRTLNELKKKNLLTADRSGIFIHDTDWLNGCN

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=222, Percent_Identity=27.9279279279279, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789756, Length=188, Percent_Identity=27.1276595744681, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25568; Mature: 25568

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLKQFMIFSGLNDEEFKQIEQIAAKRTYQPRMFVFMEGEEREAVFFIKSGLVKAFKID
CHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCEEEEEEC
EDGNEQVISILQNGDMFPHVGFFDLSPYPATAEAVQETELIVIRIADFNELLMKFPEMTI
CCCCHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
KVMQIMGKKILDLQERIQGFISKDVQHRLTHVLMKLAAEHGIPQEKGVYISLPITNQDFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHH
NMVGTSRETINRTLNELKKKNLLTADRSGIFIHDTDWLNGCN
HHHCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCC
>Mature Secondary Structure
MEFLKQFMIFSGLNDEEFKQIEQIAAKRTYQPRMFVFMEGEEREAVFFIKSGLVKAFKID
CHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCEEEEEEC
EDGNEQVISILQNGDMFPHVGFFDLSPYPATAEAVQETELIVIRIADFNELLMKFPEMTI
CCCCHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
KVMQIMGKKILDLQERIQGFISKDVQHRLTHVLMKLAAEHGIPQEKGVYISLPITNQDFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHH
NMVGTSRETINRTLNELKKKNLLTADRSGIFIHDTDWLNGCN
HHHCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]