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The map label for this gene is speA [H]

Identifier: 52785441

GI number: 52785441

Start: 1639952

End: 1641442

Strand: Reverse

Name: speA [H]

Synonym: BLi01681

Alternate gene names: 52785441

Gene position: 1641442-1639952 (Counterclockwise)

Preceding gene: 52785443

Following gene: 52785440

Centisome position: 38.87

GC content: 49.56

Gene sequence:

>1491_bases
ATGAAGGTGGGAAAACAATTGTTGCAGCACGAAACACCCCTATATACCGGATTAAAAAAACACGCCGGCAAAAACCCGAT
CCAGTTCCATATACCGGGGCACAAAAAAGGCTCTGGGATGGACCCTGAATTCAGGGAGTTTATCGGAGAAAATGCATTAA
GCATAGATTTAATCAACATCGAGCCTCTCGACGATCTGCACGCGCCGAAAGGAATAATCAAACAGGCGCAGGATCTGGCG
GCTGAAGCATTCGGAGCCGACTACACGTTCTTTTCCGTCCAGGGAACGAGCGGCGCCATCATGACGATGGTCATGGCCGT
ATGCGGACCCGGAGACAAAATCATCGTCCCGAGAAATGTTCATAAATCGGTGATGTCAGCGATCGTCTTCTCAGGCGCCG
TACCGATCTTCATCCATCCGGAAATCGACGATGAGCTGGGGATTTCACACGGGATCACCCCTGAATCAGCGAAAAAAGCG
CTGCTTGAGCATCCTGACGCAAAAGGACTGCTCGTCATCAACCCGACTTATTTCGGCATAGCTGCAGACTTAAAAAGCAT
CGTCGAGCTGGCTCATTCTTTTCATGTCCCGGTGCTAGTTGACGAGGCGCACGGCGTTCATATCCACTTCCATGAAGATC
TGCCTCTTTCGGCAATGCAGGCCGGAGCGGATATGGCGGCGACGAGCGTTCATAAGCTCGGAGGATCCCTTACACAAAGT
TCGATTCTCAATATGAAAGAAGGTCTGGTTTCAAAGGAAAGGGTGCAATCGATTTTAAGCATGCTGACGACGACATCGAC
CTCCTATCTATTGCTCGCTTCGCTTGATGTCGCCAGAAAACGCTTAGCCACAGAGGGACACGAACTGATCGAACAAACGA
TTAAGCTCGCCAACGAAACAAGGGAACGCATCAATAATATCAACGGGATTTCATGCGTCGGGAGGGAAATCCTCGGCTCC
AAAGCGGCTTTTGACTATGATCCGACCAAATTGATCATATCTGTGAAAGACCTCGGCCTGACCGGTCATGATGTGGAAAA
ATGGCTGCGCGAGTCATGCCAAATCGAAGTGGAGCTTTCTGACTTATACAACATCCTGTGCATTTTTACACCGGGAGACC
GGAAAGAGGATGCAGATGCGTTAATTAAAGGATTAACCGAGATTGCTCAACAGGCCGCTTCATCTGCGGAAAACAGACGC
AAGCCTGAAGTGCTTCTGCCAAACATTCCGGCGCTTGCGATGACACCGCGTGACGCTTTTTACGCAAACACGGAGATCAT
TCCGTTCAAAAAAGCAGCTGGCAGAATGATTGCCGAGTTTGTTATGGTTTATCCGCCAGGGATACCGATCTTCATTCCGG
GCGAGATCATTACCGAGGATAATATCAACTACATCGAAAAGAACCTGGAAGCTGGGCTGCCTGTTCAGGGACCGGAAGAT
GACACCCTCCATATGATCCGCGTTATTAAAGAACAGCAGGCAATCCTGTAA

Upstream 100 bases:

>100_bases
ACATAATATAATTCATTTGTTTTATGCCATCAAGCAAAAACGCAAAATAACTCAACGATTTTTGATAAAGAATAGTCTTT
AAGGAAATAGCAGGTTTATC

Downstream 100 bases:

>100_bases
AAACATAAAAGCATGCGGCACTGTAAATGGCCGCATGCTTTTTTCTATTCTTCCTCTTTAAGATGGCAGTTGCACTGTCC
GCACGTTCCGTAAAGTATCG

Product: SpeA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MKVGKQLLQHETPLYTGLKKHAGKNPIQFHIPGHKKGSGMDPEFREFIGENALSIDLINIEPLDDLHAPKGIIKQAQDLA
AEAFGADYTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNVHKSVMSAIVFSGAVPIFIHPEIDDELGISHGITPESAKKA
LLEHPDAKGLLVINPTYFGIAADLKSIVELAHSFHVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQS
SILNMKEGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGHELIEQTIKLANETRERINNINGISCVGREILGS
KAAFDYDPTKLIISVKDLGLTGHDVEKWLRESCQIEVELSDLYNILCIFTPGDRKEDADALIKGLTEIAQQAASSAENRR
KPEVLLPNIPALAMTPRDAFYANTEIIPFKKAAGRMIAEFVMVYPPGIPIFIPGEIITEDNINYIEKNLEAGLPVQGPED
DTLHMIRVIKEQQAIL

Sequences:

>Translated_496_residues
MKVGKQLLQHETPLYTGLKKHAGKNPIQFHIPGHKKGSGMDPEFREFIGENALSIDLINIEPLDDLHAPKGIIKQAQDLA
AEAFGADYTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNVHKSVMSAIVFSGAVPIFIHPEIDDELGISHGITPESAKKA
LLEHPDAKGLLVINPTYFGIAADLKSIVELAHSFHVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQS
SILNMKEGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGHELIEQTIKLANETRERINNINGISCVGREILGS
KAAFDYDPTKLIISVKDLGLTGHDVEKWLRESCQIEVELSDLYNILCIFTPGDRKEDADALIKGLTEIAQQAASSAENRR
KPEVLLPNIPALAMTPRDAFYANTEIIPFKKAAGRMIAEFVMVYPPGIPIFIPGEIITEDNINYIEKNLEAGLPVQGPED
DTLHMIRVIKEQQAIL
>Mature_496_residues
MKVGKQLLQHETPLYTGLKKHAGKNPIQFHIPGHKKGSGMDPEFREFIGENALSIDLINIEPLDDLHAPKGIIKQAQDLA
AEAFGADYTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNVHKSVMSAIVFSGAVPIFIHPEIDDELGISHGITPESAKKA
LLEHPDAKGLLVINPTYFGIAADLKSIVELAHSFHVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQS
SILNMKEGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGHELIEQTIKLANETRERINNINGISCVGREILGS
KAAFDYDPTKLIISVKDLGLTGHDVEKWLRESCQIEVELSDLYNILCIFTPGDRKEDADALIKGLTEIAQQAASSAENRR
KPEVLLPNIPALAMTPRDAFYANTEIIPFKKAAGRMIAEFVMVYPPGIPIFIPGEIITEDNINYIEKNLEAGLPVQGPED
DTLHMIRVIKEQQAIL

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=593, Percent_Identity=25.1264755480607, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786384, Length=553, Percent_Identity=24.7739602169982, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI221142684, Length=394, Percent_Identity=27.1573604060914, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082193, Length=568, Percent_Identity=22.887323943662, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786909, Length=367, Percent_Identity=22.8882833787466, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54123; Mature: 54123

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGKQLLQHETPLYTGLKKHAGKNPIQFHIPGHKKGSGMDPEFREFIGENALSIDLINI
CCHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEC
EPLDDLHAPKGIIKQAQDLAAEAFGADYTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNV
CCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCHH
HKSVMSAIVFSGAVPIFIHPEIDDELGISHGITPESAKKALLEHPDAKGLLVINPTYFGI
HHHHHHHHHHHCCCCEEECCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHH
AADLKSIVELAHSFHVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQS
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHH
SILNMKEGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGHELIEQTIKLANET
HHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERINNINGISCVGREILGSKAAFDYDPTKLIISVKDLGLTGHDVEKWLRESCQIEVELS
HHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEEEH
DLYNILCIFTPGDRKEDADALIKGLTEIAQQAASSAENRRKPEVLLPNIPALAMTPRDAF
HCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCHHH
YANTEIIPFKKAAGRMIAEFVMVYPPGIPIFIPGEIITEDNINYIEKNLEAGLPVQGPED
CCCCCEEECHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCHHHHHHHHCCCCCCCCCCC
DTLHMIRVIKEQQAIL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVGKQLLQHETPLYTGLKKHAGKNPIQFHIPGHKKGSGMDPEFREFIGENALSIDLINI
CCHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEEC
EPLDDLHAPKGIIKQAQDLAAEAFGADYTFFSVQGTSGAIMTMVMAVCGPGDKIIVPRNV
CCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCHH
HKSVMSAIVFSGAVPIFIHPEIDDELGISHGITPESAKKALLEHPDAKGLLVINPTYFGI
HHHHHHHHHHHCCCCEEECCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHH
AADLKSIVELAHSFHVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQS
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHH
SILNMKEGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGHELIEQTIKLANET
HHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERINNINGISCVGREILGSKAAFDYDPTKLIISVKDLGLTGHDVEKWLRESCQIEVELS
HHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEEEH
DLYNILCIFTPGDRKEDADALIKGLTEIAQQAASSAENRRKPEVLLPNIPALAMTPRDAF
HCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCHHH
YANTEIIPFKKAAGRMIAEFVMVYPPGIPIFIPGEIITEDNINYIEKNLEAGLPVQGPED
CCCCCEEECHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCHHHHHHHHCCCCCCCCCCC
DTLHMIRVIKEQQAIL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]